پرو فیسر عبدالحق کی اس تصنیف میں حرف آغاز کے علاوہ چودہ مقالہ جات اور پانچ تبصرے شامل ہیں ۔ حرف آغاز میں ان مضامین کے حوالہ سے آپ لکھتے ہیں:
یہ مضامین دوستوں کی فرمائش اور خود اپنی طبیعت کے تقاضوں کے زیر اثر لکھے
گئے تاثرات ہیں۔ (13)
اس کتاب کا جو حصہ " تبصرے" کا عنوان لیے ہوئے ہے اس میں حفیظ ملک کی کتاب پر تبصرہ کیا گیا ہے۔ پروفیسر عبد الحق تبصرہ کرتے ہوئے لکھتے ہیں:
فکر اقبال کی یک رخی تصویر پیش کر کے علمی دیانت داری سے انحراف کا کوئی
جواز نہیں ہے۔ (14)
پروفیسر عبد الحق کے نزدیک اقبال کو پاکستان کا شاعر فلسفی کہنا صرف سیاسی مصلحت آمیزی ہے۔ مجموعی طور پر کتاب کے مضامین اور تبصرے پروفیسر عبدالحق کی اقبال شناسی کے لیے راہیں تلاش کرنے میں معاونت کرتا ہے۔ پروفیسر عبد الحق کے نام کے ساتھ” ایمرٹس“ لکھا ہے۔ یہ اعزازی عہدہ ہے اور جسے یہ اعزازی عہدہ دیا جاتا ہے وہ تا حیات پروفیسر کہلاتا ہے۔
WRKY transcription factors belong to one of the biggest superfamilies of proteins in higher plants. WRKY proteins participate in plant growth for instance, gamete formation, seed germination and are also responsive to different types of environmental cues including abiotic and biotic stresses. The DNA-binding site of WRKY factors is well established which interact with W‐box (TGACC(A/T)) located in the promoter of their target genes and promote the activation or repression of the expression of those genes to control their response against stresses but it remains difficult to establish thefunctions of every family members to control particular transcriptional programs during development or in response to environmental signals. This review summarizes the recent progress madein unraveling the various WRKY protein-controlled functions under different environmental stresses.
Biochemical changes in women with gestational diabetes mellitus (GDM) and healthy pregnant women (HPW) were studied. 103 GDM women and 97 HPW were selected and registered for the study from the admitted pregnant women of Gynea Ward of Khyber Teaching Hospital, Peshawar. Sociodemographic and other pregnancy related information, including monthly-income, age, body mass index (BMI), parity, previous history of gestational diabetes and family history of diabetes, were collected on a well-designed questionnaire. Fasting blood sugar (FBS), random blood sugar (RBS), glycosylated hemoglobin (HbA1c), hemoglobin (Hb), platelet count (PC), total cholesterol (TC), triglycerides (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), liver function tests namely alanine amino transferase (ALT), alkaline phosphatase (ALP), serum bilirubin, renal function tests namely urea, creatinine, and hormones like insulin, prolactin, cortisol, triiodothyronine (T3), thyroxin (T4) and thyroid stimulating hormone (TSH) were determined by standard procedures using recommended kit for each procedure. The data were statistically analyzed using computer software, SPSS version 10. The mean monthly income of GDM and HPW was Rs.30845 ± 11107 vs Rs.28360 ± 11511, mean age was 34.01 ± 4.54 years vs 30.30 ± 5.86 years, mean BMI was 28.07 ± 2.90 kg/m 2 vs 27.30 ± 1.94 kg/ m 2 , mean parity was 5.44 ± 2.49 vs 4.95 ± 2.43, mean systolic BP was 114.80 ± 17.14 mm Hg vs 107.70 ± 19.40 mm Hg and mean diastolic BP was 86.50 ± 7.48 mm Hg vs 80.70 ± 10.02 mm Hg respectively. Age, BMI, systolic and diastolic BP was significantly higher (P<0.05) according to Pearson Chi- square test in GDM women as vicompared to HPW. The mean FBS, RBS and HbA1c of GDM women and HPW were 111.69 ± 8.70 mg/dL vs 86.59 ± 6.91, 145.45 ± 6.62 mg/dL vs 123.52 ± 9.37mg/dL and 6.58 ± 1.30 vs 4.95 ± 0.45 respectively. The FBS, RBS and HbA1c of GDM women were significantly higher than the HPW (P<0.001). The mean Hb concentration and PC of GDM women and HPW were 10.98 ± 1.12% vs 11.01 ± 1.03% and 226.31 thousand/mL vs 228.14 ± 37.61 thousand/mL. In lipid profile TC and TG of GDM group were significantly higher than the contol group (P<0.01). The mean TC of GDM and HPW was 206.01 ± 18.79 mg/dL vs 195.01 ± 24.15 mg/dL, TG was 190.12 ± 19.83 mg/dL vs 172.13 ± 21.66 mg/dL, HDL-C was 55.21 ± 8.20 mg/dL vs 56.20 ± 8.82 mg/dL and LDL-C was 93.13 ± 18.71 mg/dL vs 88.10 ± 16.36 mg/dL respectively. Liver and renal function tests of GDM women were not significantly different (P<0.05) from HPW. In liver function tests the mean ALT, ALP and serum bilirubin values of GDM women were 30.21 ± 12.47 U/L, 190.55 ± 22.20 U/L, 0.67 ± 0.41 mg/dL while of HPW were 29.64 ± 7.96 U/L, 189.95 ± 21.28 U/L, 0.58 ± 0.17 mg/dL respectively. In renal function tests the mean serum urea and serum creatinine values of GDM women were 23.70 ± 8.54 mg/dL and 0.82 ± 0.32 mg/dL while of HPW were 21.97 ± 6.16 mg/dL and 0.74 ± 0.15 mg/dL respectively. The mean insulin level of GDM women were 33.68 ± 3.69 μIU/mL, which was significantly higher (P<0.01) than the mean insulin level of HPW (29.80 ± 2.80 μIU/mL ). Among placental hormones the mean prolactin values of GDM women and HPW were 135.47 ± 9.83 ng/mL vs 131.80 ± 8.54 ng/mL and mean serum cortisol values were 734.9 ± 51.1 ng/mL vs 719.2 ± 54.7 ng/mL. The mean serum prolactin and serum cortisol values of GDM women were significantly higher (P< 0.05) when compared to HPW. No significant differences were viiobserved in the concentration of thyroid hormones. The mean TSH values of GDM and HPW were 1.72 ± 0.95 mlU/L vs 1.87 ± 0.83 mlU/L, mean T 3 values were 2.51 ± 0.62 nmol/L vs 2.62 ± 0.57 nmol/L, mean T 4 values were 103. 86 ± 14.74 nmol/L vs 105.38 ± 13.93 nmol/L. Cesarean sections (P=0.009), still birth rate (P=0.003) and macrosomic babies (P=0.001) were significantly more in GDM group.