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Separation of Some Selected Alkali and Alkaline Earth Metal Ions by Inorganic Ion Exchangers

Thesis Info

Author

Shabana Taj

Department

Department of Chemistry, QAUid-I-Azam University

Program

PhD

Institute

Quaid-i-Azam University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2012

Thesis Completion Status

Completed

Page

xxx, 253

Subject

Chemistry

Language

English

Other

Call No: DISS/Ph.D.CHE/1057

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676718574725

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عشقی الہاشمی

عشقی الہاشمی
عشقی الہاشمی(۱۹۰۹ء ۔۱۹۸۳ئ)کا اصل نام جعفر علی اور عشقیؔ تخلص کرتے تھے۔ عشقیؔ سیالکوٹ کے سادات نقوی خاندان میں ہوئے۔ آپ عربی فارسی میں خدا داد قابلیت رکھتے تھے اور علومِ شرقیہ کے بہترین اساتذہ میں شمار ہوتے تھے۔ عشقیؔ نے شاعری میں علی طالب الہٰ آباد ی اور لسان الہند مرزا ہادی عزیز لکھنوی سے فیض حاصل کیا۔ سیالکوٹ میں عشقیؔ کے بہت زیادہ شاگرد تھے۔ جنھوں نے اُردو شاعری میں اعلیٰ مقام حاصل کیا۔ اصغر سودائیؔ اور تابؔ اسلم جیسے کاملِ فن شعرا عشقیؔ کے تلمذ میں رہے۔(۴۴۱)
آپ نے مجلہ در’’نجف‘‘ میں بحیثیت مدیر معاون کام کیا۔ ’’شبابِ اردو‘‘ ،اور’’نوروز‘‘ کی ادارت بھی سنبھالی ۔اور امر تسر کے ہفت روزہ ’’مجلہ آرٹ‘‘ کے مدیر بھی رہے۔ (۴۴۲) ’’سر شک بہار‘‘ ،’’مطلع الانوار‘‘ ،’’سوزو ساز‘‘ ،’’سہا و سمن‘‘ اور ’’غزلستان‘‘ عشقیؔ کے چار شعری مجموعے ہیں۔’’العروض ‘‘تصنیف میں فنِ شاعری پر تنقید اور تبصرے شامل ہیں۔(۴۴۳)
عشقیؔ روایتی شاعر ہیں ان کے ہاں کوئی جدت نظر نہیں آتی۔ عشقی ؔ کے اسلوب پر دبستان دہلی اورلکھنو کے اثرات بھی دیکھے جا سکتے ہیں ۔ اُن کی غزلیات چھوٹی اور لمبی بحروں میں ہیں ۔شاعری میں قافیہ اور ردیف پر بہت زور دیتے ہیں ۔ان کی اکثر غزلیات کی طویل ردیفیں ہیں ایسا لگتا ہے جیسے وہ شاعری پر قافیہ اور ردیف کو فوقیت دیتے ہیں ۔ مذکورہ بالا خامیوں کے باوجود عشقیؔ کے ہاں آفاقی موضوعاتِ شاعری بھی موجود ہیں۔ اخلاقیات،رجائیت،قومیت،حقیقت پسندی،اصلاح ،عشقِ مجازی اور عشقِ حقیقی عشقیؔ کی شاعری کے اہم موضوعات ہیں۔ اس حوالے سے نمونہ کلام ملاحظہ ہو:
قوم پر جب زوال آتا ہے

نوجوان بے لگام ہوتے ہیں

جن کو جینے کا آ گیا طریق

ان کے اونچے مقام ہوتے ہیں

جو بشر احترام کرتے ہیں

ختم نبوت تورات و انجیل کى تعلیمات کى روشنى میں

Seal of Prophet-hood (Khatam-e-Nabuwat) is one of the critical issues which Islam has particularly emphasized to such a degree that a person cannot enter in the fold of Islam or may remain a Muslim without it. People, who believed in Torah & Gospel also believed that a prophet of mercy will descend with clear signs of prophet-hood. He will lead the world and guide them to the righteous path and will disclose the changes in Gospel. They also believed that the Prophet Muhammad (PBUH) will reveal the prophet-hood of Jesus and confirm that Jesus is a man of Allah with bestowed miracles. The world knows that the complete code of life after Moses was given only to the last Prophet Muhammad (PBUH). The prophet-hood has been sealed with Hazrat Muhammad (PBUH) is proven from Holy Quran as well as from Torah & Gospel. Torah & Gospel openly declare the prophet-hood of Hazrat Muhammad (PBUH) as “The Stone of Corner”. So the Holy Prophet (PBUH) himself announced the seal of his prophet-hood which none of the prophets of Bani Israel claimed in their lives. The prophet Jesus (A.S) also made efforts to clarify this point in front of his followers through several parables. These parables openly depict the authenticity of Islam and Hazrat Muhammad (PBUH) being the seal of prophets. This article provides information regarding predictions about Hazrat Muhammad (PBUH) as the last and final of the prophets of Allah Almighty, through Old & New Testaments as justified by Holy Quran. It also explains the status and value of the belief of “Finality of Prophet-hood” according to the Islamic teachings.

Synthesis, Characterization and Biological Activities of Some Novel Five and Six Membered Heterocycles and Biheterocycles

This thesis describes the synthesis, characterization and bioassay of some novel five and six membered heterocyles and biheterocycles. Some new 2-(3,5-dimethoxy-4-methylphenyl)-4-aryl-1,3,4-oxadiazoles (1a-h) were synthesized by microwave irradiation of 3,4-dimethyoxy-4-methylhydrazide (6’) with substituted benzoic acids in the presence of thionyl chloride. Compound (1b) exhibited significant bacterial inhibition while compounds (1a), (1e) and (1f) showed significant antifungal activities. Except for compounds (1e), (1f) and (1h), the rest were active for their phytotoxic activities. Some N-aminomethyl substituted aryl-5-aryl-1,3,4-oxadiazole-2-thiones (2a-j) were synthesized. Reaction of substituted hydrazides (1’-8’) with ethanolic solution of carbon disulfide and potassium hydroxide afforded 1,3,4-oxadiazole-2-thiones as key intermediates, which were refluxed with substituted anilines and paraformaldehyde in ethanol to undergo mannich condensation to furnish N-aminomethyl substituted aryl-5- aryl-1,3,4-oxadiazole-2-thiones (2a-j). Compounds (2b) and (2g) displayed maximum bacterial inhibition whilst (2b) showed maximum antifungal activity. All compounds were phytotoxic except the compound (2h). 5-Aryl-1,2,4-triazole-3-thiones (3a-f) were synthesized by reaction of substituted hydrazides (1’-8’) with ethanolic solution of carbon disulfide and potassium hydroxide. Compound (3d) and (3e) showed maximum antibacterial activity. In case of antifungal activities compounds (3b) and (3f) were most active. Except compounds (3b) and (3f) all other were active for their phytotoxic activities. The triazoles (3a-f) were converted into corresponding 3-aryl-6-phenyl-1,2,4- triazolo-[3,4-b][1,3,4]-thiadiazines (8a-f) by the condensation with 2-bromo acetophenone. Compound (8a) and (8e) showed maximum antibacterial and antifungal inhibition respectively. All compounds except (8d) and (8e) showed positive phytotoxic activity. The substituted hydrazides (1’-8’) were also microwave irradiated with acetyl acetone to afford 3,5-dimethylpyrazoles (4a-h). Compound (4b) was most active antibacterial whilst (4a) and (4d) were most active antifungal agents. All compounds were phytotoxic except (4a), (4f) and (4h). i 1-Aroyl-3,5-diarylpyrazolines (5a-h) were synthesized by cyclization of substituted hydrazides (1’-8’) with suitably substituted chalcones (a-b). Compounds (5a) and (5c) showed maximum inhibition in case of antibacterial activities and maximum percentage inhibition in case of antifungal activities. All pyrazolines were active for their phytotoxic activities. Microwave accelerated oxa-Pictet Spengler reaction of 2-chlorophenyl ethanol with various aryl aldehydes afforded some 1-aryl-5-chloroisochromans (6a-j). Standard homologation sequence of the 2-cholobenzoic acid afforded the 2-chlorophenylacetic acid which was on esterification and reduction with sodium borohydride in tetrahydrofuran and methanol furnished the 2-chlorophenylethanol. The latter was irradiated with substituted benzaldehydes in the presence of p-TsOH acid to afford 1- aryl-5-chloroisochromans (6a-j). Isochroman (6c) showed maximum inhibition against B. subtilis whereas (6e) showed against maximum inhibition E. coli. Isochromans (6a) and (6d) were most active as antifungal agents. All compounds were active for their phytotoxic activities except (6a), (6d) and (6g). Some N-substituted morpholines (7f-j) were also prepared. Thus α-amino alcohol were protected with para-tolyl methyl sulfinate in the presence of n-butyl lithium to get N-substituted sulafanilamides (7a-e), which were cyclized with bromoethyl diphenyl sulponium triflate in the presence of sodium hydride to get N-substituted morpholines (7f-j). Deprotection of the substituted morpholines was carried out by stirring with 2 N hydrochloric acid to get morpholinium salts (7k-m). 3,4,5-Trimethoxybenzoic acid was converted into corresponding phenylacetic acid. The latter upon esterification followed by reduction with sodium borohydride in tetrahydrofuran and methanol afforded the 3,4,5-trimethoxyphenylethanol. Cyclo- condensation of phenylethanol with methyl acetoacetate in the presence of p-TsOH gave methyl isochromanyl esters (a-c) which were treated with hydrazine monohydrate to furnish the corresponding hydrazides. Condensation of the latter with acetyl acetone afforded isochromanyl pyrazoles (9a-c). Compound (9a) was most against both strains of bacteria; compounds (9b) and (9c) were most against in case of antifungal activities. All compounds were active for their phytotoxic activities except (9a), and (9c). Trimethoxyisochromanyl hydrazide (c) was treated with various substituted phenyl isothiocyanates to obtain the corresponding thiosemicarbazides (10a-e). Acid catalyzed intramolecular cyclization of thiosemicarbazides afforded the isochromanyl thiadiazoles (11a-e) whist base catalyzed intramolecular cyclization furnished the corresponding isochromanyl triazoles (12a-e). In this series compounds (11c) and (12d) showed maximum inhibition against both strains of bacteria while maximum antifungal inhibition was showed by compounds (11b) and (12c). All compounds were phytotoxic. The structures of all of the synthesized compounds were confirmed by IR, HNMR, 13CNMR and Mass analysis.