Geopolitical Dynamics: Syria's Diplomatic En-deavors in a Complex Region

 In order to prevent tensions, promote economic cooperation, and obstruct regional integration, the document emphasizes the importance of territorial and economic disputes within the Syria Territory. It highlights how diplomacy plays a key role in reaching agreements and resolving these conflicts. Regarding Syria's position regarding Israel, diplomatic endeavors are essential for resolving more general geopolitical issues. Syria's strategic location makes it a key player in trade routes, and diplomatic initiatives are aimed at ensuring economic benefits and regional stability. Syria's diplomatic landscape is further shaped by Russian support, which offers political backing in international negotiations. The Geneva Conference, Astana, and Sochi processes are important platforms for tackling the complex issues at hand, bringing together regional and international players to identify all-encompassing solutions. Overall, the document elucidates how diplomacy not only addresses territorial and economic concerns within Syria but also navigates the complexities of the broader geopolitical context, such as Syria's role in the Arab-Israeli conflict and its economic aspirations linked to trade routes. It highlights various diplomatic initiatives that can promote stability, prosperity, and mutual benefits while also fostering regional integration. Policymakers who want to use diplomatic means to advance peace and stability in this region will find this information useful. Keywords: Syria, Diplomacy, Geneva, Astana, and Sochi.

Molecular Analysis of Gnrh1 Gene Sequence in Infertile Male Patients

There are various causes of human male infertility and various genes might be involved. Gene under study for present research work was GNRH1 (Gonadotropin Releasing Hormone 1). For this study 40 samples of males with abnormal semen analysis report were collected from different diagnostic centers with informed consent. Then DNA was extracted. Primers were designed for GNRH1 gene and amplified through PCR. Sequencing was outsourced and bioinformatics tools were applied to analyze the sequenced data. There were 14 variations at different positions identified in this study in GNRH1 gene. Variations observed at position c.1325+40 and c.1325+181 mentioned in literature as rs2709608 but predicted that it has no significant effect on protein, whereas rs1453947741 have not been cited in any research article till date which is associated with deletion of A at position c.1325-144. It is potential target site and shows significant change affecting splicing. No data has been found which state the disease causing variations of diagnosed positions in my study. The study concluded that GNRH1 gene has certain variations and splicing might have effect on intronic variations which result in diseased condition and might have role in association with human male infertility.