صادق جب لکھنے بیٹھا ہے
حمد سے ہی آغاز کیا ہے
ساری تعریفیں اُس کی ہیں
پہلے اُس کا نام لیا ہے
روزی روٹی اُس کے ذمے
بن مانگے سب کو دیتا ہے
کیڑے پالے پتھر اندر
بھوکا کوئی نہیں سوتا ہے
ہندو مسلم فرق نہیں ہے
ہر کوئی نعمت کھاتا ہے
اک ہم ہیں نا شکرے بندے
اور وہ کرم کیے جاتا ہے
اُس کے موسم اُس کی بارش
وہ جب چاہے برساتا ہے
اُس کی فصلیں اُس کی کھیتی
دانے سے خوشا بنتا ہے
صادقؔ کیا تعریف لکھے گا
بس فعلن فعلن کرتا ہے
Islam recognizes the right of individual ownership of material things in this world. A person can hold all kinds of Halal material things in his individual possession. However, Islamic Shari'a doesn't allow such a concept of individual ownership which is given in Capitalism and as adopted by Western world. The Western world's concept about individual ownership is very liberal and without any restrictions. While, Islam doesn't give full liberty to any individual but rather instructs them to own and possess Halal material things via legitimate sources, and also instructs the right usage of these material things in the light of Qur'an and Sunnah. The benefit of this Islamic law is that disqualified individuals, such as an insane person or children, have no right on disposing his or her individual property. Similarly, in the eyes of Islam, an individual person is not allowed to dispose his or her property in such a way which causes trouble and inconvenience to others, for example a person cannot dig a well on his own land which causes trouble and inconvenience to others. Islam prohibits such disposing of an individual's property.
Nanoparticles have been known for their unique properties and are being utilized in various disciplines of sciences. Nanoparticles due to their smaller size enable them to higher exposure and higher availability through gastrointestinal tract when administered orally. In this research four metallic oxides nanoparticles (iron, zinc, silver and copper) along with three biological nanoparticles (turmeric, garlic and cinnamon) were synthesized. Various characterization techniques were utilized to evaluate these synthesized nanoparticles. Among the synthesized metallic nanoparticles the mean diameter of zinc oxide nanoparticles was around 47 nm, the mean diameter of iron oxide nanoparticles was around 54 nm, the diameter of silver oxide nanoparticles ranged between 40-70 nm and the diameter of copper nanoparticles ranged between 30-50 nm. Moreover, mean diameter of synthesized garlic and turmeric nanoparticles were 62 and 46 nm respectively. However, cinnamon particles turned out to be in micro ranges. To evaluate potential of these synthesized nanoparticle in Gout treatment mice were used as model organism. For this experiment mice were induced with gout by injecting them with MSU crystals. These synthesized nanoparticles were administered orally to mice in various concentrations of 5 ppm, 10 ppm and 20 ppm. Biochemical tests such as RFTs, LFTs, lipid profile and blood count were performed to evaluate the effect of these nanoparticles at various concentration on gout. From renal function tests it was observed that these nanoparticles had decreased the uric acid levels in mice thus treating gout. From these biochemical test it was observed that nanoparticles were effective in reducing serum uric acid levels among which 5 ppm AgO NPs (1.80 ± 0.3098), 5 ppm zinc (2.00 ±0.8944), 5 ppm turmeric NPs (1.550 ± 0.1517) and 20 ppm garlic NPs (1.750 ± 0.1378) showed the most significant (P<0.01) results in reducing serum uric acid in comparison to allopurinol (2.11 ± 0.3710). Furthermore, at lower concentrations nanoparticles did not cause any significant toxicity. From this research it was concluded that the synthesized zinc, turmeric, garlic and cinnamon nanoparticles have potential in treating gout. Renal function test of these groups revealed that the uric acid levels were considerably decreased as well as the swelling of ankles also decreased. Moreover, the mice which were locally administered with 5 ppm of Turmeric-oil NPs had astonishing effect in decreasing the swelling of mice ankles. Repeated oral administration of various nanoparticles at lower concentration can result in the reduction of serum uric acid levels in mice.