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Computational Analysis of Surfactin to Identify Functional Orthologs and Interaction Mechanism

Thesis Info

Author

Javeria Fatima

Supervisor

Fauzia Yusuf Hafeez

Department

Department of Bioinformatics

Program

BSB

Institute

COMSATS University Islamabad

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completion Status

Completed

Subject

Bioinformatics

Language

English

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676719587248

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پروفیسرمحمد یونس نگرامی ندوی

پروفیسر محمد یونس نگرامی ندوی
یہ خبر سن کر بڑا صدمہ ہوا کہ ۴؍ مارچ کو پروفیسر محمد یونس نگرامی کا انتقال ہوگیا، اناﷲ وانا الیہ راجعون۔ ادھر مہینوں سے ملاقات نہیں ہوئی تھی، لکھنؤ آنے جانے والوں سے ان کی علالت کی خبر ملتی تھی مگر یہ خیال نہیں تھا کہ وہ اتنی جلد رختِ سفر باندھ لیں گے۔
ان کی پیدائش لکھنؤ ضلع کے مردم خیز قصبہ نگرام میں ۱۹۴۱؁ء میں ہوئی تھی، ان کا خاندان علمی و دینی حیثیت سے ممتاز تھا، درس و تدریس، تالیف و تصنیف اور وعظ و ارشاد اس کا طرہ امتیاز تھا۔ ان کے والد مولانا محمد اویس نگرامی ندوی دارالعلوم ندوۃ العلماء لکھنؤ میں شیخ التفسیر تھے۔ وہ دارالمصنفین کے رفیق اور مولانا سید سلیمان ندویؒ کے محبوب تلامذہ میں تھے، ان کی صحبت میں مولانا کے تفسیر و قرآنیات کے ذوق کو بڑی جلا ملی، بعد میں وہ دارالمصنفین کی مجلس انتظامی کے رکن بھی ہوئے۔
پروفیسر محمد یونس نگرامی نے اپنے والد ماجد کے زیر سایہ دارالعلوم ندوۃ العلماء میں تعلیم پائی۔ پھر جامعہ اسلامیہ مدینہ منورہ گئے، لکھنؤ یونیورسٹی سے پی۔ایچ۔ڈی کی ڈگری لی، پہلے یونیورسٹی کے شعبہ عربی میں لکچرر اور اب کئی برس سے پروفیسر ہوگئے تھے۔
ان کا تحقیقی مقالہ ’’ہندوستان میں عربی زبان و ادب‘‘ کے موضوع پر تھا، ان کی دوسری کتب و رسائل کے نام یہ ہیں۔ تھوڑی دیر اہل حق کے ساتھ، خیالات، مثالی خواتین، نماز کیسے پڑھیں، تذکرہ مولانا محمد اویس نگرامی، تقدس حج، خلیجی جنگ وغیرہ۔
ندوہ اور جامعہ اسلامیہ مدینہ منورہ میں تعلیم پانے کی وجہ سے عربی لکھنے کی ان کو اچھی مشق ہوگئی تھی، ندوۃ العلماء کے جریدہ الرائد میں ’’نافذۃ علی الھند‘‘ و (ہندوستان کے دریچے سے) کا مستقل کالم ان ہی کے قلم سے ہوتا تھا، البعث الاسلامی میں بھی ان...

The Preservation and Authenticity of Ḥadīth As a Source of Sīrah: A Critique of Robert Spencer’S Views on Historicity of Muḥammad

The account of the deeds and sayings of the prophet (ﷺ) has been carefully preserved since the dawn of Islam. This is what actually led Ernest Renan to believe that “[Islam] was born in the full light of history”, and that the life of Muḥammad (ﷺ) can be known as explicitly as that of any sixteenth century reformer. Notwithstanding, some contemporary writers doubt the historicity of Muḥammad (ﷺ) ; Robert Spencer is one of them. He is an American author. He is quite famous for his criticism of Islam and the prophet of Islam. He has published twelve books so far. He is a member of Melkite Greek Catholic Church. He contends that Muḥammad’s (ﷺ) historical value is in no way greater and more reliable than mythological figures or characters such as Robin Hood and Macbeth. He maintains that the very idea of subjecting the traditionally accepted account of the life of Muḥammad (ﷺ) and the origins of Islam will be regarded by many Muslims as an affront. To substantiate his argument, he rigorously criticizes the historical value of ḥadīth. He argues that aḥādīth were fabricated and compiled in the third century. He maintains that aḥādīth were concocted much later to be used as weapons in political strife and religious controversies. This paper is an academic attempt to prove that aḥādīth were painstakingly preserved and for that purpose various techniques were employed. Besides, it also sheds light on the reasons for the fabrication of aḥādīth and the ways and means utilized for sifting the genuine aḥādīth from forgeries. Findings of this article suggest that the minute details of the life of Muḥammad (ﷺ) have been scrupulously preserved; hence aḥādīth can be used as a reliable source of Sīrah.

Some Vertex-Degree-Based Topological Indices of Graphs

Many topological indices which are being used by researchers in the quantitative structure-property relationship (QSPR) and quantitative structure-activity relationship (QSAR) studies to predict the physico-chemical properties of molecules, are based on vertex degrees of the corresponding molecular graphs. When a new topological index is introduced in chemical graph theory, one of the important questions that need to be answered is for which members of a certain class of n-vertex graphs this index assumes minimal and maximal values? On the other hand, there are many well known graph families and vertex-degree-based topological indices in the literature for which this question remains open. The main purpose of current study is to address this open question for some well known families of graphs. Firstly, the collection of all k-polygonal chains (for k = 3, 4, 5) with fixed number of k-polygons is considered and the extremal elements from this family are characterized with respect to several well known bond incident degree (BID) indices (BID indices form a subclass of the class of all vertex-degree-based topological indices). From the derived results, many already reported results are obtained as corollaries. Furthermore, the extremal 4-polygonal (polyomino) chains for some renowned vertex-degree-based topological indices (other than BID indices) are also determined. Next, the problem of characterizing the extremal cacti over the certain classes of cacti (tree-like polyphenylene systems, spiro hexagonal systems and general cacti) with some fixed parameters is addressed for various well known vertex-degree-based topological indices. Finally, some mathematical properties of the atom-bond connectivity index and augmented Zagreb index are explored