مولانا اخلاق حسین قاسمی دہلوی؍ حکیم عزیز الرحمان مؤی؍ ڈاکٹر مقتدی حسن ازہری
افسوس ہے کہ گذشتہ دنوں ہماری مجلس علم و دانش کو مولانا اخلاق حسین قاسمی دہلوی، حکیم عزیز الرحمان مؤی اور ڈاکٹر مقتدی حسن ازہری جیسی اہم شخصیتوں سے محروم ہونا پڑا، قرآن مجید اور علوم دینیہ کی تبلیغ، تفہیم اور توسیع میں ان کی خدمات لائق تحسین رہیں، دارالمصنفین سے ان حضرات کا تعلق اخلاص و تعاون کا تھا، معارف میں ان تینوں کی نگارشات آتی رہیں، افسوس ہے کہ اب ان کی جگہ لینے والے نظر نہیں آتے، اﷲ تعالیٰ ان تمام مرحومین کے حسنات کو قبول کرے اور جنت الفردوس کی نعمت سے نوازے، معارف میں ان کا ذکر تفصیل سے آنا چاہیے، آئندہ شماروں میں شاید یہ ضرورت پوری کی جاسکے۔ ( عمیر الصدیق دریابادی ندوی ، نومبر ۲۰۰۹ء)
Women’s rights and freedom is one of the most debated subjects and the flash point of contemporary world. Women maintain a significant place in the society catered to them not only by the modern world but also by religion. Yet, the clash between Islamic and western civilization is that they have defined different set of duties for them. Islam considers women an important participatory member of the society by assigning them inclusive role, specifying certain fields of work to them, given the vulnerability they might fall victim to. Contrarily, Western world allows women to opt any profession of their choice regardless of tangible threats they may encounter. Apparently, the modern approach seems more attractive and favorable, but actually this is not plausible from Islamic point of view. Intermingling, co-gathering and sexual attraction of male and female are creating serious difficulties and problems for both genders, especially for women. Women are currently running many movements for their security, rights and liberties under the umbrella of “Feminism”. Due to excess of freedom and lack of responsibility, a radical movement came into existence which was named as ‘Radical Feminism’. This feminist movement is affecting the unique status of women in the whole world, especially in the west. This study seeks to explore radical feminism and its major impact on socio-religious norms in addition to its critical analysis from an Islamic perspective. Analytical research methodology will be adopted in this study with qualitative cum quantitative approach. This study reveals that the radical feminism has some notorious impacts on ethical, social and religious norms of the society, with especial reference to Muslims. Thus, it is a dire need of time to encounter these impact and consequences in the light of legal and moral approaches.
Acute myocardial infarction and ischemic stroke are caused by thrombosis or the obstruction of blood vessels with clots and this is the leading causes of death. The single handling accessible is the use of thrombolytic agent to liquefy the blood lump. Hyper production of streptokinase was carried out in this research work. Beta hemolytic Streptococcus equisimilis was isolated from indigenous sources and then mutagenesis of this isolate was carried out by means of chemicals as well as radiations. To seek the optimum activity, different kinetic and thermodynamic parameters like pH, temperature, Km, Vmax, molecular weight, melting temperature, half-life, enthalpy and entropy etc. were applied on the purified enzyme. UV irradiated strain resulted in 335 U/mL activity with 1116.66 U/mg specific activity, 0.30 mg/mL protein, 41.92 fold purification and 69.79% recovery whereas Sodium azide derived mutant resulted in 400 U/mL activity with 2000 U/mg specific activity, 0.20 mg/mL protein, 71.94 fold purification and 64.51% recovery of the finally purified enzyme. Gamma irradiated strain exhibited 300 U/mL activity with 1428.57 U/mg specific activity, 0.21 mg/mL protein, 59.52 fold purification and 75.94% recovery whereas ethidium bromide derived mutant showed 365 U/mL activity with 1659.09 U/mg specific activity, 0.22 mg/mL protein, 66.52 fold purification and 85.08% recovery. Optimum pH and temperature of the finally purified enzyme was 7 and 45oC. Enthalpy of denaturation (ΔH*) of streptokinase at 450C was 43.67 kJ/mole. The Energy of thermal denaturation ΔG* was 101.14 kJ/mole and entropy of inactivation ΔS* was -197.32 kJ/mole at 45oC. The negative value of ΔS* indicated that streptokinase was thermodynamically stable. Km and Vmax values of streptokinase were 26.31 mM and 50 MS-1. Streptokinase produced from sodium azide derived mutant exhibited activity within the pH range of 6 to 8 while it presented its best performance at pH 7. Thermal stability between 45oC to 80oC was shown by the streptokinase along with half-life of 244 minutes while less stability was shown at 80oC along with 45 minutes of half-life and 40.41 kJ/mole as enthalpy of denaturation (ΔH*).