اقبال سہیلؔ
افسوس ہے کہ گزشتہ مہینہ اقبال سہیلؔ بھی چل بسے ۔وہ مسلم یونیورسٹی علی گڑھ کے باقیاتِ صالحات اور اُس عہد کی دیرینہ روایات کے حاملین میں سے تھے۔غیر معمولی ذہین وذکی تھے ۔فارسی اور اردو دونوں زبانوں کے بلند پایہ شاعر تھے۔ وہ اگر وکیل نہ ہوتے یامزاج لااُبالی نہ ہوتا توعلم وادب کے میدان میں ان کی شہ سواری کا مقابلہ بہت کم لوگ کرسکتے تھے ۔طبیعت حددرجہ دقیقہ رس اور دماغ بڑا نکتہ آفریں پایاتھا۔ نغز گوئی کے ساتھ اشعار میں روانی غضَب کی ہوتی تھی۔ غزلوں اور نظموں کے علاوہ انھوں نے جو نعتیہ نظمیں لکھی ہیں وہ بھی بڑے معرکہ کی ہیں، نثر بھی بہت اچھی لکھتے تھے ۔اگر کوئی صاحب اُن کے مضامین ِ نثر و نظم کو مرتب کرکے یک جا شائع کردیں تویہ اردو ادب کی مفید اورلائقِ قدر خدمت ہوگی۔ورنہ ان ادبی جواہر پاروں کے ضائع ہوجانے کا اندیشہ ہے ۔حق تعالیٰ مغفرت وبخشش کے فضل ِ خاص سے نوازے ۔ [دسمبر۱۹۵۵ء]
The correct recitation of the Quran depends upon correct spellings is based on "Ilm al-Rasm" and accurate reading depends upon "Ilm al-Dabt". "Ilm al-Dabt" is divided into “Nuqat al-A’rab” and “Nuqat al- A’jam”. “Nuqat al-A’rab” mean the signs which throw light on ‘al-Harakah’, ‘Sukun’, ‘Tashdid’ and ‘Madd’ etc. “Nuqat al-A’jamm” implies the signs which remove the confusion found between letters and cause the phonetic and facial recognition different letters. So dotted letters are titled “Mu’jam” and dotless letters are named as “Muhmal”. This paper deals with “Nuqat al-A’rab”. Initially, the Quran was without these signs. This science was developed first time in the period of Amir Muawiah by Abu al-Aswad al-Duali in the shap of rounded dots. Later on these dots were replaced with appropriate signs by Khalil bin Ahmad al-Farahidi. These signs were given different names. Ilm al-Dbt gained a little controversy but the majority of scholars appreciated it.
This study was aimed to prepare polyherbal formulations for weight loss considering six herbs: Allium sativum, Plantago ovata, Nigella sativa, Carum copticum, Trigonella foenum-graecum and Syzygium aromaticum. This study was carried out in five phases: Preparation and formulation, Pharmacological and biological activities, Phytochemical investigations, efficacy trial on animals (rabbits and guinea pigs) and human trials. Irradiation was performed using “Cobalt 60” (dosages of 10 and 5 kGy) as the source on polyherbal formulations for shelf life extension before using in efficacy trial. Crude methanolic extract (Crd. MeOH Ext.) and different fractions of all selected plants were investigated for various pharmacological and biological activities including, antibacterial, antifungal, phytotoxic and insecticidal. The pharmacological / biological investigations revealed that C. copticum possesses significant antifungal activity in Crd. MeOH Ext. against Trichoderma harzianum (91%), while Crd. MeOH Ext. of S. aromaticum showed significant activity against Penicillium oxalicum (85%), chloroform (CHCl3) extract of A. sativum showed significant activity against Verticillium lecanii (87%), Crd. MeOH Ext. of N. sativa showed significant antibacterial activity against Escherichia coli (89%), Proteus mirabilis (96%), Bacillus cereus (89%) and Xanthomonas oryzae (88%). The plant materials showed significant phytotoxic effects against Lemna minor at higher concentrations; Crd. MeOH Ext. of N. sativa showed good growth regulation (75%) at 1000 µg/mL, moderate growth regulation (50%) at 100 µg/mL and low growth regulation in aqueous fraction (30%) at 10 µg/mL concentrations;Crd. MeOH Ext. of A. sativum, C. copticum and S. aromaticum showed significant insecticidal activity (90, 90 and 100%, respectively) against Tribolium castaneum. The phytochemical investigations showed that the quantity of tannin (0.54 mg/100 g), alkaloids (0.45 mg/100 g) and flavonoids (0.058 mg/100 g) was increased by the use of irradiations while vitamin C showed a slight decrease of 5 mg/100g. Efficacy trials on animals showed decrease in body weight and cholesterol level, while increased serum glutamic transaminase (SGPT) level. The alkaline phosphatase and bilirubin levels were normalised by the use of polyherbal formulations. Haemoglobin and platelets were increased in number, while monocytes, eosinophil, neutrophils and lymphocytes remained unchanged in both rabbits and guinea pigs. Human efficacy trials by use of polyherbal formulations for a period of two months exhibited decrease in body weight, body measurements, low density lipoprotein (LDL), alkaline phosphatase, fasting glucose and total cholesterol levels, while increase was observed in platelets count, haemoglobin level and high density lipoprotein (HDL) level. No changes were reported for monocytes, eosinophil, neutrophils and lymphocytes counts. For shelflife extension, the polyherbal formulations were exposed to different irradiation doses of 10 and 5 kGy (source: Cobalt 60) and then compared with un-irradiated samples. In this case, same results were found. Statistical package for social sciences (SPSS) version 16 was used for the calculation of results; two-way, one-way ANOVA and chi-square tests were used (P< 0.05).