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Computational Study of Cytochrome B Gene in Most Popular Vertebrate Animals

Thesis Info

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Author

Mavish Zaheer

Institute

Virtual University of Pakistan

Institute Type

Public

City

Lahore

Province

Punjab

Country

Pakistan

Thesis Completing Year

2017

Thesis Completion Status

Completed

Subject

Software Engineering

Language

English

Link

http://vspace.vu.edu.pk/detail.aspx?id=133

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676720974750

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Cytochrome b is an integral membrane protein of approximately 400 amino acids and it is widely used as a region of mitochondrial DNA for determining Phylogenetic relationship between organisms due to sequence variability. It is considered to be most useful in determining relationship between families and genera. Comparative studies involving cytochrome b have resulted in new classification scheme and have been used to assign newly described species to genus as well as to deepen understanding of evolutionary relationship. The sequence variability of cytochrome b makes it most useful for the comparison of species in the same genus of the same family. The result obtained in many of phylogenetic studies in which this gene has been led to the proposition ofnew classification schemes that better reflectedthe phylogenetic relationship among the species. Furthermore cytochrome b gene will help in genus assignment of newly described species. Computational analysis of cytochrome b gene will be carried out in the current study. The sequences derived will use to identify the biological origin of samples by aligning to cytochrome b sequences entries in nucleotide databases. The analysis will give the phylogenetic relationship among the various common species of vertebrate animals.Using bioinformatics tools, structure prediction, conservation analysis and docking studies will be executed. Phylogenetic trees reconstruction determined how species are related to their ancestors of various orthologous species. Multiple sequence alignment takes place by Tree based consistency objective functions for alignment evaluation.
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سلطان کھاروی دیاںکافیاں

سلطان کھاروی دیاںکافیاں

کجھ و دواناں دے وچار نیں کہ کافی عربی زبان دا لفظ اے جیدے معنی نیں مکمل ، پورا یا کافی ہونا۔ کیوں جے قرآن مجید وچ ربی فرمان اے۔

’’ کفیٰ باللہ شہیدا                               اللہ دی گواہی کافی اے ‘‘ (۱)

’’ کفیٰ باللہ وکیلا                              اللہ کارساز کافی اے ‘‘(۲)

’’قرآن حکیم وچ ایہہ لفظ کافی تے مکمل دے معنی وچ استعمال ہویا اے۔ ایس لئی شاعری دی اجہی صنف نوں کافی آکھیا گیا ہے۔ جہدے وچ اک مکمل مضمون اک مکمل خیال یاں اک مکمل جذبے دا اظہار کیتا گیا سی۔ شاعری دی ایس صنف نوں پڑھ کے یاںسن کے ہور کسے صنف یاں شاعری دے مطالعے یاں سنن دی لوڑ نہیں رہندی ۔ کیوں جے ایہدے راہیں بیان ہون والا مضمون یاں خیال ، ادبی ذوق ، روحانی لوڑاں تھوڑاں تے وجدان دی مکمل حد تک تسکین کر دیندا اے۔ ایسے پاروں شاعری دی ایس صنف نوں کافی آکھیا گیا اے۔‘‘(۳)

کافی تے سنگیت دا آپسی گوہڑا سمبندھ ہے ۔ کافی وچ سنگیت پکھ اگھڑواں ہوندا اے۔ ایس لئی سنگیت توں بنا ں کافی مکمل نہیں ۔جے ایہہ آکھیا جاوے کہ شاہ حسین نے کافی تے سنگیت نوں لازم و ملزوم بنا دتا اے تاں کجھغلط  وی نہ ہووے گا۔ اونہاں اپنیاں کافیاں بارے واضح شبداں وچ لکھ دتا، پئی ایہہ کافی فلاں راگ یاں راگنی وچ گائی جاوے مثال دے طور تے اوہناں نے اپنی ایس کافی نوں راگ جے جے ونتی وچ گاون دی ہدایت کیتی اے۔

 

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