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Home > Molecular Based Identification and Association of Mycobacterium Tuberculosis, Hbv and Hiv Virus in Patient Samples of Muzaffargarh District

Molecular Based Identification and Association of Mycobacterium Tuberculosis, Hbv and Hiv Virus in Patient Samples of Muzaffargarh District

Thesis Info

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Author

Khadija Tul Kubra

Institute

Virtual University of Pakistan

Institute Type

Public

City

Lahore

Province

Punjab

Country

Pakistan

Thesis Completing Year

2018

Thesis Completion Status

Completed

Subject

Software Engineering

Language

English

Link

http://vspace.vu.edu.pk/detail.aspx?id=244

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676721004807

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Hepatitis is a major disease spreading more rapidly in all over Pakistan and its detection is increasing day by day. Knowledge of the distribution of Hepatitis B and HIV virus have important clinical implications since the efficacy of current and new therapies. The treatment of chronic Hepatitis B virus (HBV) infection has the potential to change significantly over the next few years as therapeutic regimens are rapidly evolving. However, the burden of chronic infection has not been quantified at the global level using the most recent data. Cohort and cross sectional study 534 blood samples randomly selected patients of pulmonary or extrapulmonary tuberculosis (T.B) was calculate utilizing Quantitative Polymerase chain reaction (qPCR). We examined Hepatitis B and HIV virus by ELISA and confirmation by qPCR. Risk factors estimated and study association among the triple or Co-infection of Hepatitis B virus, HIV virus, and mycobacterium tuberculosis in dissimilar period of life and groups of patients. Distribution of co-infection was diverse in regions. Decision between the 534 positive T.B patients analysis, 498 (93.2%) patients were negative and 36 (6.7%) were positive for HBV and 04 patients were positive for HIV (0.74%) by using the qPCR technique. The transference of HBV was estimated to have take place by and large between ages of 20-40, unmarried, poor and illiterate. Detection rate is high of HBV in males rather than females. There was developed a correlation between co-infection of HBV, HIV and tuberculosis patients due to low immunity and body mass index (BMI). We found that HBV can be effect on TB patients. Active tuberculosis is leading to the cause of death living with HBV and HIV virus. There is need for standard operating protocols (SOP?s) for better management of tuberculosis patients.
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