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Home > Role of Rs6265 Polymorphism of Bdnf in Migraine Patients of Punjab Pakistan

Role of Rs6265 Polymorphism of Bdnf in Migraine Patients of Punjab Pakistan

Thesis Info

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Author

Savera Hassan

Institute

Virtual University of Pakistan

Institute Type

Public

City

Lahore

Province

Punjab

Country

Pakistan

Thesis Completing Year

2019

Thesis Completion Status

Completed

Subject

Software Engineering

Language

English

Link

http://vspace.vu.edu.pk/detail.aspx?id=273

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676721012076

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Brain has long been considered as the origin of mental processes. In order to understand the development and state of migraine, one must look at the structure of brain, the genetics of the individual, and their life style. Migraine is a common neurological disorder. Pathophysiology of migraine is much complex and genetic factors along with environmental factors also contributes in the development of migraine. Migraines are characterized with recurrent headache, nausea, vomiting, photophobia and phonophobia. Migraine being a neurological disorder, known as the 13th major medical disorder among all the other major medical disorders spreading all across the world. International Headache Society divided migraine into two categories; as migraine with aura (MA) and migraine without aura (MO). In developing countries like Pakistan, patients of migraine took it as simple headache due to lack of awareness and prefer to do home medications instead of proper medical check-up. Study was based on assessment of blood samples which were collected from both migraine patients as well as control group of healthy people to know about the cause of migraine and to check the involvement of gene contributing to migraine. DNA was collected through inorganic method of extraction from blood samples, to perform PCR and RFLP-PCR for the assessment of SNP rs6265 of gene BDNF. But results obtained showed no association of rs6265 SNP with the studied samples of migraine.
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The Immensely Merciful to all, The Infinitely Compassionate to everyone.

33:01
a. O The Prophet!
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d. Surely Allah is All-Knowing of what they say and what their motives are and All-Wise.

33:02
a. Instead, follow what is being revealed on to you from your Rabb - The Lord.
b. Surely Allah is All-Aware of whatever you do: your deeds, dealings, and motives.

33:03
a. And trust Allah.
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33:04
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e. whereas Allah Speaks the truth in this and all matters.
f. And thus HE Guides you along the way of truth.

33:05
a. As for your adopted children, address them by the names of their biological fathers.
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