Search or add a thesis

Advanced Search (Beta)
Home > Investigation of Oxidative Stress Enzymes and Histological Alterations in Liver, Spleen, and Heart of Tilapia Exposed to Chlorpyrifos

Investigation of Oxidative Stress Enzymes and Histological Alterations in Liver, Spleen, and Heart of Tilapia Exposed to Chlorpyrifos

Thesis Info

Access Option

External Link

Author

Muqadas

Institute

Virtual University of Pakistan

Institute Type

Public

City

Lahore

Province

Punjab

Country

Pakistan

Thesis Completing Year

2019

Thesis Completion Status

Completed

Subject

Software Engineering

Language

English

Link

http://vspace.vu.edu.pk/detail.aspx?id=402

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676721043732

Asian Research Index Whatsapp Chanel
Asian Research Index Whatsapp Chanel

Join our Whatsapp Channel to get regular updates.

Similar


Chlorpyrifos (ChF) is widely used in agricultural fields and indoor for controlling pests. It sinks in the aquatic sediments and pose toxicity for aquatic organisms including fish. Therefore, the current study was designed to investigate the oxidative stress enzymes, and histological alterations in the liver, spleen, and heart of tilapia (Oreochromis niloticus) due to ChF exposure. Median lethal concentration (LC50 24 H) was calculated as 52.78 ?g/l by exposing fish with different acute concentrations (0, 1, 15, 35, 40, 45, 50, 55, 100 and 150 ?g/l) of ChF. For assessment of sublethal toxicity of ChF, the fish were divided into four groups, one group served as control (C) while three groups (ChF1, ChF2, ChF3,) were exposed to three sublethal doses of ChF. ChF1 group was treated with 3.51 ?g/l (1/15th of LC50) of ChF whereas, ChF2 and ChF3 groups were treated with 5.27 ?g/l (1/10th of LC50) and 10.55 ?g/l (1/5th of LC50) of ChF respectively for 14 days and oxidative stress enzymes, biochemical parameters, behavioral changes and histological alterations were evaluated. It was found that level of Glutathione-S-Transferase (GST), Catalase (CAT), and Superoxide dismutase (SOD) increased significantly (p=0.05) in the gills and liver of tilapia treated with sublethal concentrations of ChF. Study of morphological features exposed that fish in the control groupshowed significantly increase in weight and length (p=0.05) as compared to ChF treated fish. The behavioral changes as reduced feeding rate, eratic swimming, increased surface gulping, aggregation in the corner of tank, hemorrhage, and darkening of skin coloration was observed in all ChF treated groups. The significant elevation in level of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) was observed in all groups treated with different sublethal concentrations of ChF. Histological study of liver tissues shown increased number of kupffer cells, hydropic degeneration, dilated sinusoids, congestion, necrosis, and hemorrhage in liver of fish from all treatment groups. In the spleen of fish exposed to ChF increased number of melanomacrophage centres (MMCs), necrosis, congestion, and hemorrhage was detected. Disorganized muscle fibers, cardiac muscle fiber degeneration, coagulative necrosis, congestion in blood vessel and necrosis was perceived in the heart of ChF treated fish. This study concluded that sublethal concentrations of ChF can induce oxidative stress and histological alterations in the tissues of tilapia.
Loading...
Loading...

Similar Books

Loading...

Similar Chapters

Loading...

Similar News

Loading...

Similar Articles

Loading...

Similar Article Headings

Loading...

منشی عطاء اﷲ

منشی عطاء اﷲ 
افسوس ۲؍ فروری کو دارالمصنفین کے مخلص اور قدیم کارکن منشی عطاء اﷲ صاحب نے داعی اجل کو لبیک کہا، ان کا اصلی وطن کیرانہ ضلع مظفرنگر تھا، ۱۹۱۶؁ء میں دارالمصنفین میں پریس قائم ہوا تو ان کے بڑے بھائی منشی عبدالحفیظ صاحب مرحوم نے اس کے انصرام کی ذمہ داری قبول کی، ان ہی کے ساتھ یہ بھی اعظم گڑھ آکر شعبۂ طباعت سے وابستہ ہوئے، جب کبرسنی کی وجہ سے ملازمت ترک کرنی چاہی تو سید صباح الدین صاحب مرحوم کا شدید اصرار اس میں مانع ہوا، پھر اپنے سعادت مند فرزند ڈاکٹر محمد نعیم ندوی کے اصرار سے گھر پر آرام کرنا منظور تو کرلیا لیکن ان کا دل دارالمصنفین ہی میں لگا رہتا تھا، اس لیے جب تک قوت رہی برابر دوسرے تیسرے روز یہاں آتے رہے، وہ طبعاً نیک، صلح پسند اور دیندار تھے، اپنی دینداری کی وجہ سے اپنے اکلوتے بیٹے ڈاکٹر محمد نعیم ندوی کو حفظ کرانے کے بعد ندوہ میں داخل کیا، جو فراغت کے بعد دارالمصنفین کے رفیق رہے اور اب ابوظہبی کے محکمۂ شرعیہ سے وابستہ ہیں، منشی عطاء اﷲ صاحب اپنی نیکی، بھلمنساہت اور ملنساری کی وجہ سے شہر میں مقبول تھے، اﷲ ان کی مغفرت فرمائے اور متعلقین کو صبر جمیل عطا فرمائے۔
(ضیاء الدین اصلاحی، فروری ۱۹۹۲ء)

 

Pengaruh Kinerja Kepegawaian Dalam Administrasi Perkantoran

Penelitian ini bertujuan untuk mengetahui dan menganalisis hubungan pengaruh kinerja kepegewaian dalam administrasi perkantoran di kantor camat kecamatann Tuhemberua kabupaten Nias Utara. Populasi dalam penelitian ini adalah pegawai Kantor Camat Kecamatan Tuhemberua yang berjumlah 12 orang. Jenis data yang digunakan dalam penelitian ini adalah data primer. Teknik pengumpulan data dengan angket, wawancara, observasi, ujian (test) dokumentasi. Teknik analisis data dengan melakukan verifikasi data, pengelolaan angket, dan pengolahan data: (a). Uji validitas data, (b). Uji reliabilitas data, dan (c). Pengujian hipotesis. Dari hasil perhitungan koefisien korelasi diperoleh rhitung (rxy) = 0,834 jika dikonsultasikan pada tabel harga kritik r produk moment untuk interval kepercayaan 5% setelah di hitung rhitung = 0,834 > rtabel = 0,576. Berdasarkan regresi linear sederhana maka sumbangan kinerja kepegawaian terhadap administrasi perkantoran di Kantor Camat Gunungsitoli Tuhemberua 2,668. Dari perhitungan koefisien determinasi besarnya pengaruh variabel x terhadap variabel y di Kantor Camat Gunungsitoli Tuhemberua 69, 48%. Berdasarkan kriteria pengujian hipotesis ternyata Ha adanya pengaruh dan H0 tidak adanya pengaruh, sebab thitung = 7, 20 > rtabel = 2,160 sehingga dapat dinyatakan adanya pengaruh kinerja kepegawaian terhadap administrasi perkantoran pada kantor camat Tuhemberuaa kabupaten Nias Utara.

Factors Affecting Working Capital Management Practices and Determining Firms Performance: A Comparative Analysis of Listed Companies in Pakistan

In order to produce good financial results and improve operational performance, a firm should effectively and efficiently manage its working capital. Working capital policies and practices vary from firm to firm which leads to variation in profitability. A difference in working capital practices is observed on the basis of size and location. Review of existing literature indicates that this variation in working capital management practices among various categories of firms such as small, medium, large, domestic and multinationals has not yet been adequately researched, particularly in developing countries like Pakistan. The study uses secondary data of 153 listed firms on Pakistan Stock Exchange for 10 years (2004-2013). These firms are categorized on the basis of size viz. small, medium and large; as well as location such as domestic and multinationals. R-square shows that highest explanatory power of the independent and control variables included in the model based on market to book ratio occur in multinational firms where dependent variable is explained to the extent of 41% whereas based on return on assets it is 26% in medium firms. Results show that working capital policy significantly affects firms’ performance. Multinomial logistic regression model was used to identify factors significantly affecting WC policy. Logistic regression results show that ROA and MC are the variables determining the WC policy of firms significant at 5% and 1% respectively. Overall, correct predictions for the study employing logistic regression model work out to be 71.9% showing fitness of the model used for analysis.