تفسیر قرآن میں ام المؤمنین سیدۃ عائشه کا مقام

Quran is the absolute and error free source of knowledge for all mankind. The words and meanings of the Quran both have been revealed by Allah and will remain unchanged for ever. The holy Quran was explained by the Holy prophet and by sahaba as well. Later on different scholars of Islam have made notable contribution in this regard. Many companions of the Holy prophet are famous in the explanation of the Holy Quran. Although Syyeda Aeshah is famous in the field of Hadith but she is one of most prominent Mufassrah of the Quran too. She has deep and correct knowledge of the Holy Quran. In this Article the status of Sayyedah Aesha in the field of tafseer has been discussed. Hopefully the readers will get useful information from this Article

Prevalence and Associated Risk Factors of Bluetongue Virus in Punjab and Balochistan

Bluetongue (BT) is a vector-borne disease of immense economic importance for small and large ruminants. Despite frequent disease reports from neighboring countries, a little is known about current disease status and prevalent serotypes in Pakistan. We screened a total of 1,312 healthy animals (sheep= 326, goat= 476, cattle= 234, buffalo= 276) from Punjab and 876 from clinically healthy sheep (475) and goats (401) from Balochistan for the detection of group-specific antibodies and serotype-specific genome for BT virus through competitive ELISA and real-time PCR, respectively. An overall prevalence of group-specific VP7 antibodies [28.81% (n= 378/1312, 95% CI=26.4 – 31.4)] was observed in Punjab. The prevalence was higher in goats [40.75% (n=194/476, 95% CI=36.4 – 45.3)] followed by buffalo [29.34% (n=81/276, 95% CI=24.3 – 34.9)], sheep [18.40% (n= 60/326, 95% CI=14.5 – 22.9)] and cattle [17.94% (n= 42/234, 95% CI= 13.56 – 23.4)]. The odds of seropositivity were more in buffalo of Nili breed (OR= 2.06, 95% CI= 1.19-3.58) as well as those found with a presence of vector (OR= 2.04, 95% CI= 1.16-3.59). Buffalo and cattle with history of abortion [(OR= 3.95, 95% CI= 1.33-11.69) and (OR= 5.89, 95% CI= 1.80-19.27) respectively] were much likely to be infected with the disease. Serotype 8 was detected in all animal species while, serotypes 4 and 6 were detected in sheep, 2, 6 and 11 in goat, and 2 and 16 in buffalo. The study concludes a much frequent exposure of different serotypes of Bluetongue virus (BTV) in small and large ruminants and indicates its expansion to enzootic range worldwide.In Balochistan, none of the study herds (n = 97) were seronegative for BTV, and at the individual level, the overall prevalence of BTV seroconversion was 47.26% (n = 414/876, 95% CI=43.92-50.63%). A higher percentage of goats (50.87%, 95% CI = 45.99-55.73%) were seropositive for anti-VP7 immunoglobulins (IgG) than sheep (44.21%, 95% CI= 39.81-48.70%). Odds of seroconversion for goats were associated with breed-type (χ2 = 16.84, p = 0.01), parity (χ2 = 23.66, p = 0.00) and presence of vector (χ2 = 2.63, p = 0.10), whereas for sheep, it was associated with breed-type (χ2 = 13.80, p = 0.01) and parity (χ2 = 53.40, p = 0.00). The presence of vector was also observed to be a risk factor in goat. Serotype 8 was the most prevalent (26.82%, 95% CI=14.75-43.21%) followed by an equal prevalence of serotypes 2 and 9 (7.31%, 95% CI= 1.91-21.01%). To the best of our knowledge, this is the first study conducted in Balochistan province and the results indicate that there is a necessity to initiate intervention strategies to control BT disease burden not only in this region of Pakistan but also in adjacent areas of the neighboring countries, Iran and Afghanistan.