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Insilico structure prediction, superimposition, multiple sequence alignment and phylogentic analysis of genes involved in non-syndromic deafness

Thesis Info

Author

Ayesha Ilyas

Supervisor

Tahira Noor

Department

Department of Bioinformatics and Biotechnology

Program

BS

Institute

International Islamic University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2014

Thesis Completion Status

Completed

Page

114

Subject

Bioinformatics & Biotechnology

Language

English

Other

BS 611.01816 AYI

Added

2021-02-17 19:49:13

Modified

2023-01-24 16:54:05

ARI ID

1676721509426

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رئیس احمد جعفری

رئیس احمد جعفری
پچھلے دنوں پاکستان میں ہمارے ایک اورفاضل اورعزیز دوست رئیس احمد جعفری کابھی انتقال ہوگیا۔مرحوم نے تعلیم ندوہ اورجامعہ دونوں میں پائی تھی لیکن تکمیل کسی ایک جگہ بھی نہیں کی۔تحریر کاشوق اور سلیقہ شروع سے تھا اورآدمی تھے بڑے ذہین اور طباع! اس لیے اپنے مطالعہ اورمحنت کے بل بوتہ پر اردوزبان کے نامور ادیب اورمصنف بن گئے۔ ان کاقلم ہی ان کے لیے ذریعہ معاش تھا، اس لیے اگرچہ کوئی ڈھنگ کاعلمی اورتحقیقی کام نہیں کرسکے لیکن افسانہ وناول سے لے کرمذہب اورتاریخ وفلسفہ تک ہر موضوع پر چھوٹی بڑی کتابیں اس کثرت سے لکھی ہیں کہ اس وصف خاص میں ان کاکوئی معاصر ہمسری کادعویٰ نہیں کرسکتا۔ان کاقلم بڑاشگفتہ اوررواں دواں تھا ان کے ساتھ میراذاتی تعلق یہ تھا کہ مرحوم کے نانا سید امتیاز احمد صاحب (ریاض خیرآبادی مرحوم کے حقیقی بھائی) آگرہ میں کوتوال شہرتھے۔ان میں اور میرے والدصاحب قبلہ میں نہایت گہرے برادرانہ تعلقات تھے ۔کوتوال صاحب کے متعلقین ہمارے ہاں آتے اور ہفتوں قیام کرتے تھے ۔ اسی طرح ہم لوگ ان کے ہاں جاتے اور ہفتہ دو ہفتہ ٹھہرتے تھے۔رئیس احمد جعفری کوتوال صاحب (جن کومیں خالو کہتا تھا)کی پہلی بیوی کی لڑکی کے بطن سے تھے۔ان تعلقات کے باعث مرحوم جب تک دہلی میں رہے برابر آتے جاتے رہے ۔جب کبھی ملتے تھے بڑی محبت سے پیش آتے تھے۔ آخری مرتبہ دہلی آئے اور میں ان دنوں ہندوستان سے باہر تھاتولاہور جاتے ہوئے دفتر برہان میں میرے نام ایک خط چھوڑ گئے جس میں لکھا تھا بڑی حسرتوں اور تمناؤں کے ساتھ آیاتھا کہ تم سے ملاقات ہوگی مگر مایوس جارہاہوں۔اب میں بیمار رہنے لگاہوں ، نہ جانے کتنی اور باقی ہے۔البتہ یہ تمنا ضرور ہے کہ مرنے سے پہلے ایک مرتبہ تمہیں اور دیکھ لوں۔‘‘ صدحیف تمنا پوری نہیں ہوئی،اور وہ خدا کو پیارے...

Justice System of Islam in the Form of Qisas, Diyat and Harabah for the Protection of Human Dignity

For peace in a society and to protect the lives and properties of all the individuals living in a society, it is necessary that there must be certain rules and regulations that govern the whole system of society.  A guideline for each and every aspect of human life should be there. For this purpose Islamic law or Shariah law took origin to govern an Islamic state and for avoiding injustice and to preserve human dignity Shariah law prescribes different forms of punishment which constitute the basic criminal justice system of Islam. These include Qisas, Diyat and Harabah. Thus, the Quran not only specifies principles of retaliation in the form of Qisas but also gives an option of monetary compensation (blood money Diyat) to the aggrieved family of the victim. The fear of the consequences in the form of punishments prescribed by the Shariah Law must be there in a person's mind before he commits a crime and this fear will abstain from violating human dignity by destroying his life and property.

Study on Vertebrate Fauna, Status and Impacts of Environmental Pollution on Wetland Chotiari Reservoir Sindh

The present study was undertaken to document vertebrate fauna (richness and abundance of mammals, birds, reptiles and amphibians) at Chotiari Reservoir, to determine their status and to assess the impacts of anthropogenic factors, if any, on the reservoir and its vertebrate biodiversity. Chotiari Reservoir complex includes wetlands, which altogether, have been identified by Bird Life International as an Important Bird Area. Further, the complex fulfills certain criteria of Wetland of International Importance-Ramsar Site. A total of 203 vertebrate species belonging to 29 orders and 78 families were recorded from Chotiari Reservoir during 2006- 2010. These included 32 species mammals (14 medium and large sized mammals and 18 small mammals); 136 bird species (53 water birds, 48 passerine birds, 13 birds of prey and 22 miscellaneous birds); 32 species of reptiles (a single species of crocodile, 3 species of turtles, 15 species of snakes and 13 species of lizards) and 3 species of amphibians (1 toad and 2 frog species). As many as 136 bird species belonging to 19 orders and 48 families were recorded. Out of 136 birds, summer fauna and winter fauna constituted 69.11 % and 34.55 % respectively. It was found that alteration in the ecological conditions of the area after the construction of the Chotiari Reservoir had changed the avifauna species composition of the area. A total of 32 reptile species belonging to three orders and 14 families were recorded. These included three species of turtles (9.37%), 15 species of snakes (46.87%), 13 species of lizards (40.62 %) and one crocodilian species of (3.12 %). vMeans of total number of individuals recorded during 2006-2009 at 0.05 level were not significantly different indicating no change in the abundance of selected wildlife species during study period. It was, inferred, therefore that the wildlife diversity must have not been affected. However, distribution of threatned species of the area, such as Smooth-coated otter and Marsh Crocodile, might have been impacted. Based on present study data, the reservoir water was unpolluted, and reservoir is not connected with any source of industrial or municipal effluent. The concentration of heavy metals recorded during the study period as well as selected physico-chemical parameters were within safe limits and were below water quality standards of WHO (World Health Organization). Further, no evidence of the reservoir’s water contamination by industrial and agriculture runoff was recorded, for the reservoir did not have any industry in its surroundings nor could the water from the surrounding croplands enter in to the reservoir mainly because of two reasons. First, the land within the reservoir is not used for agriculture, and secondly drainage from the croplands is not carried in to the reservoir. However, changes in land use practices, habitat modification, hunting, unregulated fishing, overexploitation, community-wildlife conflict and trapping of wildlife species were identified as major issues affecting wildlife species composition and abundance.