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Home > Genetics of neurodegenerative movement disorders in Pakistani population.

Genetics of neurodegenerative movement disorders in Pakistani population.

Thesis Info

Author

Usmani, M. Asad

Supervisor

Muhammad Arshad

Department

Department of Bioinformatics and Biotechnology

Program

MS

Institute

International Islamic University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2015

Thesis Completion Status

Completed

Page

153

Subject

Bioinformatics & Biotechnology

Language

English

Other

MS 611.01816 USG

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676721596684

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مولانا محمد الیاس کاندھلوی

مولانا محمد الیاس کاندھلوی
وادریغا!مولانا محمد الیاس کاندھلویؒ نے چند ماہ کی شدید علالت کے بعد ۱۲/ جولائی بروز پنج شنبہ داعی اجل کو لبیک کہا اوراس جہانِ آب وگل کوخیر بادکہہ کر اپنے’’رفیق اعلیٰ‘‘سے جاملے۔مولانا کی عمر ابھی ایسی کچھ زیادہ نہ تھی۔لیکن تبلیغ کے کام میں انہماک کے باعث آپ نے اس مقدس اورضروری فریضۂ اسلام کے علاوہ ہرچیز کو قطعاً فراموش کررکھا تھا۔یہاں تک کہ سینکڑوں دیکھنے والوں نے دیکھا کہ مرض الموت میں بھی جب کہ آپ پر عالمِ سکرات طاری تھا اور ضعف ونقاہت اورمرض کے پے بہ پے حملوں کے باعث آپ کاجسم ناتواں ہڈیوں کاایک ڈھانچہ ہوکر رہ گیاتھا۔جو کوئی شخص آپ کی مزاج پرسی کرتا اورمرض کی کیفیت دریافت کرتا آپ اس پر خفگی کااظہار کرتے اور فرماتے تھے’’میرا مرض تم لوگ ہو جوتبلیغ کے فرض سے غافل ہو،بس اس کے سوا مجھے کوئی اوربیماری نہیں۔‘‘
آپ درحقیقت فنانی التبلیغ تھے۔ہرآن اسی کی دھن تھی۔یہی ایک خیال اور یہی ایک جذبہ تھا جوسیماب کی طرح ان کو بے چین اورمتحرک رکھتاتھا۔عمل اور اخلاص کاحقیقی پیکر تھے۔دل خشیتِ ربانی سے معمور تھا۔تقریر اگرچہ رسمی فصاحت و بلاغت سے عاری تھی۔مگر غایت اخلاص وﷲیت کی وجہ سے ایک ایک لفظ جو دل سے نکلتا تھا سننے والوں پر تیروسنان کاکام کرتا تھا۔حقیقت یہ ہے کہ آپ کی پوری زندگی اتباع سنت کاکامل نمونہ تھی۔مولانا مرحوم کی ان صفات کاہی یہ اثر تھا کہ آپ نے چند سالوں میں ہی اصلاح وتبلیغ کے میدان میں وہ کچھ کردکھایا جوسالہا سال میں بڑی بڑی جماعتیں بھی نہیں کرسکتیں۔دعا ہے کہ اﷲ تعالیٰ اعلیٰ علیین میں مولانا کے مراتب ومدارج بیش ازبیش بڑھائے اورآپ اپنے پیچھے جو کام چھوڑ گئے ہیں،آپ کے جانشین مولانا محمد یوسف صاحب اوران کے اعوان و رفقاء ان کاموں کوباحسن وجوہ قائم وبرقرار رکھ سکیں۔رحمہ اﷲ رحمۃً واسعۃً وتغمدہ...

GENERALIZED ANXIETY DISORDER AND ITS ASSOCIATED FACTORS AMONG FEMALE STUDENTS

Background and Aim: To determine the Generalized Anxiety Disorder and its association with factors like hormonal changes, chronic illness among female students of university. Methodology: Perceptions and preferences of Female Students were determined in well-organized Institute (Superior University) with ages between 16-28 years old of all disciplines. Electronic self-administrated questionnaires consisting of two parts; demographics factors (Age, Gender, Designation, education Discipline, socioeconomic status and medical history) and Generalized Anxiety Disorder GAD-7, were then filled by the participated female students with sample size of 231. Then the perceptions and preferences were evaluated using a pre validated questionnaire (GAD-7) from previous research article. Results: A total of 231 responses were returned. All respondents were females. About (62.7%) of total respondents reported feeling nervous, anxious, or on edge to some degree; 10% of respondents said that they experience this feeling nearly every day. A significant proportion of respondents reported mild to moderate anxiety levels. The mean score of anxiety scale was 3.87±3.32 with minimum and maximum score of 0 and 19. The study findings give us a better considerate that Traumatic disorders (39.4 %), hormone issues (45.2%), were the main causes of anxiety. 39.8% indicated that they had a family history of anxiety. Overall, moderate to high levels of anxiety among the participants were observed. Conclusion: These results illustrate the need to devise treatment strategies to alleviate symptoms of generalized anxiety and reduce the prevalence of Generalized Anxiety Disorder among students. It is suggested that to decrease the level of anxiety among university students, regular counseling sessions should be implemented.

Effect of Feeding Probiotic Yeast on the Fecal Bacterial Community of Buffalo

Probiotic yeast has been frequently used in animal feed to improve gut microbiota. The gut bacterial community of dairy cattle is very important, because it may influence milk yield and animal health. However, knowledge related to fecal-associated bacterial communities is still very poor. It was hypothesized that feeding probiotic yeast (Yea-Sac ) would improve the microbial population in the gastrointestinal tract of dairy cattle (buffaloes) by analyzing the fecal matter. In this study, the impact of dietary addition of commercially available probiotic yeast (Yea-Sac 1026 ) on the fecal population of some target species related to gut microbes (i.e., Escherichia coli, Enterococcus, Lactococcus, Bacillus, Lactobacillus, Salmonella, Bifidobacterium spp.) was evaluated. For this purpose, six buffaloes were used as experimental animals and two equal groups having three buffaloes (in each) were formed i.e, control feed and experimental probiotic yeast feed group. For two month trial period (60 days), control feed group animals were fed on with routine diet whereas experimental feed group animals were fed on the same diet with addition of commercially available probiotic yeast (Yea-Sac 1026 ) 10g/day/animal. The fecal samples were collected on 1 1026 day. Fecal matter (1gm) was collected individually in disposable bags and used for determining the number of Lactobacillus, Bifidobacterium, E. coli, and Salmonella species. Morphological and biochemical tests of all selected bacterial strains were performed. Results showed that a large bacterial diversity was present in the fecal samples of buffaloes. The relative proportion of beneficial (Lactobacillus, Bifidobacterium) bacteria as well as pathogenic (E.coli and Salmonella species) bacteria were altered by feeding commercially available probiotic yeast (Yea-Sac st , 30 th and 60 th ). So, it is suggested that the commercial probiotic yeast (Yea-Sac 1026 ) can be used to promote the beneficial bacteria in GIT of buffalo to sustain the balance of healthy microbial population and it also helps in reduction of pathogenic bacterial population