حسن پرستی ساڈا شیوہ، ماریا دم حضوری دا
فائدہ توں اٹھا نہ سجناں ساڈی ایس مجبوری دا
دودھ تاں پانی پایا ملدا، پوڈر وی ہن پایا اے
بھانویں لکھ پئے خالص لیے دودھ ہن کالی بوری دا
عاشقاں دے نال کیوں نہیں کردے بندے سوہنے باتاں
کوئی تاں حل ہن کرنا پئے گا مسئلے اس مزدوری دا
واعظ مینوں عشقوں روکے آکھے پڑھ صلواتاں نوں
مطلب میں ایہہ سمجھ نہیں سکیا، اوہندی گل ادھوری دا
جتھے یار نیں روٹیاں لائیاں اوتھوں روٹی کھانی ایں
بھانویں پھلکا ہکو دے دے مینوں اوس تندوری دا
پڑھ درود کروڑ سلاماں ہر دم ذات محمدؐ تے
ایہو ذکر خدا ملائکہ، خاکی، آبی، نوری دا
کر کر زُہد عبادتاں تھکے، یار نہ ملیا جا کے مکے
جیہڑے عشق دی بازی جتے، انھاں قرب حضوری دا
Cardiovascular diseases (CVDs) are the top most cause of morality around the world. It is predicted that the number casualties from CVDs will increase to more than 24 million till 2030 people. Medicinal plants provide the major raw materials for medicine preparations. They are gaining high consideration due to their effectiveness and increasing cost of modern medicines. Many successful drugs are plant based, including aspirin from the willow bark, morphine from opium poppy, quinine from the cinchona bark, and digoxin from the foxglove. According to World Health Organization (WTO), ~70% to 80% of people around the world rely on herbal sources for the treatment of their disease. Plant sources are endorsed due to the fact that they contain an optimal amount of antioxidants and phytochemicals that help to avoid and treat many diseases. Phoenix dactylifera L. Particularly Ajwa variety, is the most rich in phytonutrientsthat can benefit to control many cardiovascular diseases. It contains6 vitamins (vitamin A, C, B1, B2, B3 &riboflavin), high amount of fibers, Potassium, Magnesium and 23 amino acids which play a healthy role towards hypertension, muscular contractions, and blood pressure control. It has been studied that Niacin (B3) helps to control cholesterol and low density lipoprotein levels (LDL), as high cholesterol is the one of the main cause of cardiovascular diseases so, Ajwa could be a vital regulatory source. According to the findings of Sabbah M. Et al, Ajwa extracts significantly improved the DNA integrity and also reduced the cardiomyocytes congestion, edema and the cellular stress wielded on cardiac muscles resulting the restoration of cardiomyocytes architecture in Doxorubicin (DOX) induced cardiotoxicity in rats. Research done by Alqarni et al, proves that Ajwa extracts has successfully decreased the LDL‐C, VLDL‐C, and triglycerides concentration. Additionally, treatment with ajwa pulp also improved the HDL‐C level and antioxidant enzymes activity. In another invivo study, Ajwa preparation has successfullydecreased the diclofenac-induced pulmonary and hepatic instabilities. Vitamin-K play important role in blood coagulation, and in case of anticoagulant therapy, activity of vitamin-K controlled by drugs (warfarin) that sometimes causes serious side effects. According to the reported data, Salicylic acid is the vitamin-K antagonist and has capability to block the action of vitamin K during the coagulation pathway. Dates contain ~3.75 to 4.50 mg/100 g of salicylic acid. Thus, providing anticoagulation effect too. So, the limelight of the reported data provides an enough reason that plants can be used as primary source of drug designing for the cardiovascular disease. They hold true momentum to address the increasing healthdiseases, which cannot be lost to distraction or apathy. Fight against the burden of CDVs, is affecting all countries and specially, under developing and the poor countries.
Among the numerous abiotic stresses restricting the crop production, salinity stress is the most significant one. Estimation of genetic variability and development of suitable selection criterion are fundamentals for development of salinity tolerant types of crop plants. Sixty accessions of Brassica napus were evaluated for salinity tolerance using hydroponics technique. Six sensitive and ten tolerant lines were selected and crosses were attempted in line × tester fashion. The resultant F1 crosses and their parents were evaluated at seedling stage using hydroponic culture technique and at maturity stage in a pot experiment. Data were recorded on various seedling (root length, shoot length, fresh root weight, fresh shoot weight, dry root weight, dry shoot weight, proline content, Na+/K+ ratio, osmotic potential) and morphological traits (days to 50% flowering, days to 50% maturity, plant height, number of primary branches, number of silique per plant, seeds per silique, oil content, thousand seed weight, yield per plant). Recorded data were analyzed to estimate the genetic variability, general and specific combining ability effects, heterosis, gene action and association among traits. Results showed that genetic variability existed in present breeding material that may be used in development of high yielding salinity tolerant Brassica napus. Combining ability analysis revealed that lines ZMR-2 and R-3 and testers Faisal and Shirlaee for seedling traits and lines R-3 and 23627 and tester Faisal for morphological traits were best general combiners for most of the traits under normal and salinity stress conditions. Crosses R-3×Laclone, RBJ-8007×Laclone and ZMR-1×ZMR-3 were best specific combiners for most of the traits under all treatments. Cross RBJ-8007×Laclone also had significant and positive mid parent, better parent and commercial heterosis for most of the traits under control and salinity stress treatments. Correlation and path analysis revealed that number of silique per plant, oil contents, days to 50% flowering and days to 50% maturity may be used as selection criteria for development of salinity tolerant types with higher yield as they showed significant association with yield per plant under salt stress conditions.