زندگی سے ہارا آدمی
میں نے طور پہ آدمی کو پکارا
تو ہانپتا ہوا بے بس چہرہ سامنے آ گیا
میں اس کا قصیدہ لکھوں
یا اس کی حالت زار کا مرثیہ بیان کروں
وہ آدمی جس کے حال پر،سوال پر، خیال پر
میں افسوس کے سوا کچھ نہیں کر سکتا
جس نے اپنے ظاہر کو روشن کرنے کے لیے باطن کو جلا دیا
زر بناتے ہوئے اصلِ زر کو بھول گیا
گھر کو ریستوران بنا لیا اور پائوں کو پہیے لگا لیے
گویا اپنے پائوں کاٹ لیے
اس تیز رفتاری میں اتنا آگے نکل آیا کہ تنہا رہ گیا
اپنے وجود سے بیزار
زندگی سے ہارا ہوا
دوست میسر نہیں، بس یادیں ہیں
تصویریں دستیاب ہیں مگر بولتی نہیں
بس اتنا سا جواب’’ وقت نہیں ملتا‘‘
’’بہت مصروفیت ہے آج کل‘‘
کاش وہ تصویریں بھی بولتی جو دل میں بسی ہیں
کبھی مسکراتی، کبھی رنجیدہ ہوتیں
اب تو انسان بھی تصویر دکھائی دیتا ہے
میں اس تنہائی کے مارے آدمی سے اکتا گیا ہوں
ان روشن راتوں اور ان سیاہ دنوں سے گِھن آنے لگی ہے
میرا دل تو اب مجھ سے وہی پرانا آدمی مانگتا ہے
محبت، پیار، خلوص اور ہمدردی سے بھرا،دانا آدمی
Pakistan is an Ideological country, there are only two ideological states in the world. First one was Madinah (Saudi Arabia) and the second one is Pakistan. Political situation in our country is worst. There is no any stability in political situation. From its existence Pakistan is facing different problems and issues. In this research article, will try to draw reasons and will table solutions to get political stability in Pakistan.
Living organisms are equipped with sophisticated mechanisms to minimize the hazards and threats offered by the nature and maximize their survival potential against strain imposed by environmental forces. Growing concern about the frequent use of analogous antibiotics leading to resistant pathogens and their harmful impacts on crop yield worldwide has fuelled an explosion in the field of plant defense response by coupling biotechnology to the medicinal plants. Increasing knowledge of the mechanisms underlying plant defense response has also encouraged the idea that sensitizing a plant towards microbial elicitors increases plant resistance to the potential pathogens. Considering the same thought of knowledge, this study was entailed to examine the bioactive potential of Silybum marianum under control and fungal stress. Peptide based multidimensional studied of the plant with reference to antimicrobial, antioxidant, antitumor, cytotoxic and mutagenic potential were undertaken. A time course study of the extracts prepared under fungal stress strongly revealed the increased accumulation of proteins/peptides upto 8 hours post inoculation with a drop in the expression level at subsequent hours. Encouraging results regarding antibacterial potential towards gram negative species and highly significant antifungal potential were also observed. In addition to antimicrobial potential, plant also showed beneficial traits as antitumor and nonmutagenic against Agrobacterium tumefaciens and human cell lines respectively. As far as antioxidant and cytotoxic potential is concerned, all the extracts had excellent antioxidant capacity whereas among all, 8 h control and its treated time points showed slight cytotoxicity. Rewarding bioactive potential of Silybum marianum eventually led to the identification of peptides involved in cellular metabolism, plant growth and development, signal transduction and exclusively to the peptides involved in defense response. Antimicrobial gene isolation with subsequent cloning and heterologous expression has proved substantial pharmaceutical importance of the plant which may open novel avenues for biotechnological applications in agriculture.