توریہ کی حقیقت، ضرورت اور اس کا حکم: ایک تحقیقی جائزہ

Islam is a religion of peace, love and prosperity. It emphasis on moral values and strongly forbids from immoral acts. Commitment to the former is ultimate way to the paradise, while the latter leads to Hell, which is an abode, where deviants from the righteousness are punished for their misdeeds. The Holy Prophet Muhammad (ﷺ) showed the importance of morality through the deeds and actions. “Ta┴riyā” is an act which is a part of morality. It is an act which escapes a human being from telling a lies strongly forbidden in Islam, being a root cause of manly social avoid. Usually“Ta┴riyā” is adopted so as to avoid differences and turmoil on a group of individuals. By“Ta┴riyā” means speaking a statement which is equivoques i.e. At the same it gives too meaning apparent and the hidden. Now the question arises whether “Ta┴riyā” is considered as lie or truth. It cannot be termed either lie or truth. However, in many traditions, it has been negated as a lie. At some occasions, when a person feels to tell a lie, for the sake of bringing peace, then it is advised than he should bring on use the act of “Ta┴riyā” but. The reality manipulated be in such a way so it could be termed as lie.

Study of Organometallics

A series of novel and biologically potent organometallic complexes using Nheterocyclic carbenes (NHCs), cephalosporin derivatives, quinolilone derivatives, vitamins and antiviral molecules as ligands has been synthesized. The geometry of the synthesized ligands and their metal adducts are done through state of the art spectral tools like NMR (1H, 11B, 19F) UV/Visible and FT-IR. It is confirmed through these spectral studies that in the NHCs the metal is bonded through the active carbine side while in other classes metal is bonded through either oxygen or through nitrogen in some cases. After synthesizing the ligand and the metals molecules are subjected to a variety of biological tests like, antibacterial, antifungal, antioxidant, Positron emission topography and ADMET studies in order to evaluate the bio-potential of the synthesized molecules. Some of the selected compounds are screened with various microorganisms like Gram positive bacteria, Gram negative bacteria and with some fungi. The results obtained are quite impressive, it can be shown that ligands in its free state possess less activity while it is clear from the results that their activity shifts to greater extent while treated with various metals. This clearly shows that metals are responsible for the bioactivity. Further, the molecular docking study was also carried out for Tin(IV) Schiff bases complex in order to correlate the biological experimental results. As in the parent study the Tin(IV) Schiff base complexes derived from piperenol and Entecavir exhibit excellent biological results which were further confirmed through molecular docking study. For some of the molecules ADMET study was also carried out in order to check/correlate the experimental data. ADMET study also confirmed the experimental results. It can be concluded from the present study that the organometallic complexes/metal molecules can serve as potent agents in curing many diseases and may prove their role as future metal base drugs.