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Doctor patient communication and patients satisficationa cross sectional study of walk clinics of general physicians of Islamabad

Thesis Info

Author

Zain Tariq

Supervisor

Muhammad Baber Akram

Department

Department of Sociology

Program

BS

Institute

International Islamic University

Institute Type

Public

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2014

Thesis Completion Status

Completed

Page

v,69

Subject

Sociology

Language

English

Other

BS 301 ZAD

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676723628863

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گدڑ دی چالاکی

گدڑ دی چالاکی

اک دفعہ دا ذکر اے کہ کسے پنڈ وچ اک خرگوش تے اک گدڑ رہندے سن۔ دونویں آپس وچ گہرے دوست سن تے اک دوجے اتے اعتبار کر دے سن۔ گدڑ بہت چالاک تے دھوکہ باز سی۔ اوہ اپنا کم کڈھ کے دوڑ جاندا سی۔ خرگوش بھلا مانس سی، اوہ گدڑ دی چالاکی دے باوجود اوس نال پیار کردا تے کوشش کردا کہ ہر چیز ونڈ کے کھاہدی جاوے۔

خرگوش نے بڑی محنت نال سرنگ پُٹی جو اک بیکری دے اندر جا کے ختم ہو ندی سی۔ خرگوش روز سرنگ راہیں بیکری دے اندر جاندا تے ڈھڈ بھر چیزاں کھا کے واپس آ جاندا۔ خرگوش نوں انج کردیاں کئی دن لنگھ گئے۔ اک دن گدڑ نوں شک پے گیا کہ خرگوش اکلا اکلا کوئی شے کھاندا اے تے خرگوش نے ساری گل دس دتی۔ ایہہ سن کے اوہدے منہ وچ پانی آ گیا تے اوس آکھیا کہ اج مینوں وی نال لے کے جاویں۔ خرگوش تے گدڑ سرنگ راہیں بیکری دے اندر گئے تے ون سونیاں چیزاں ڈھڈ بھر کے کھاہدیاں۔ جدوں گدڑ دا ڈھڈ بھر گیا تاں اوس نے چیکاں مارنیاں شروع کر دتیاں۔ چیکاں سن کے بیکری دا مالک آ گیا۔ خرگوش ڈر دے مارے سرنگ وچ وڑ کے دوڑ جاندا اے تے گدڑ مالک دے قابو آ جاندا اے۔ مالک نے گدڑ نوں رسیاں نال بنھ بہت ماریا۔ اوس نے گدڑ نوں کھاون لئی سکیاں روٹی دتیاں، مالک روز ای گدڑ نوں کٹ دا سی۔

اک دن مالک نوں کجھ دناں لئی اک کم واسطے شہر جانا پیا۔ جاون لگیاں اوس اپنی گھر والی نوں دسیا کہ گدڑ نوں رسیاں نال بنھ کے روز کٹنا ایں تے کھاون نوں سکیاں روٹیاں دیناں نیں۔ مالک ایناں آکھ کے شہر چلا جاندا اے تے...

قیام امن میں حضرت عثمان کا کردار: تاریخی و تجزیاتی مطالعہ

Nowadays the entire world, particularly the Islamic countries, are suffering from a state of anxiety and insecurity due to terrorism. The terrorists are destroying peace of the world for the sake of their personal interests. They affiliate their terrorist activities with Islām, while Islām condemns not only terrorism, but also the violation of the country law. Islām is the religion of peace. Allāh, peace of title the with (صلى الله عليه وسلم) Muhammad Prophet His sent Almighty and granted him the name of religion as Islām. The Holy Prophet in harmony and peace of facade the build to life his all spent (صلى الله عليه وسلم) the society. His companions also exhibited human loving nature and. (صلى الله عليه وسلم) Prophet Holy the by them to provided roadmap the followed Ḥaḍrat Uthmān is one of those, who sacrificed themselves for the noble cause of peace. In this article, the remarkable efforts of Ḥaḍrat Uthmān for the maintainance of peace are highlighted. He was commited to peace even before Islām, and after accepting it, he played a vital role for the promotion and maintaince of peace. He the at (صلى الله عليه وسلم) prophet the of ambassador the as appointed was occasion of the Ḥudaybiyah Pact. Uthmān ruled a vast empire. Peace was a hallmark of his era. The evil plots against him surfaced only in the later years of his caliphate. These included objections regarding appointment and administration of the governers. He took every step to stop the disruption of peace, so much so, he did not allow the Muslims to fight for his defence, hence, sacrificed his life.

Molecular Characterization of Autosomal Recessive Congenital Ichthyosis

Autosomal recessive congenital ichthyosis (ARCI) is a genetically and phenotypically heterogeneous group of non-syndromic cornification disorders characterized primarily by generalized hyperkeratotic epidermal scales with or without erythroderma. So far, pathogenic variants in fourteen genes have been associated with ARCI most of which perturb lipid metabolism and localization during cornification, thereby disrupting the lipid envelope and thus barrier function. Research is in progress to reduce or treat the disease manifestations in affected individuals by enzyme replacement therapy and gene therapy. Moreover, gene expression studies and histopathological studies have been performed to discover more effective drug targets. However, a more precise genotype to phenotype correlation and a greater understanding of the pathophysiology would aid in developing more specific therapies. Therefore, the necessity is to elucidate the link between a defective gene and the resulting difference in expression of proteins in epidermis. In the current study whole exome sequencing (WES), Sanger sequencing and mass spectrometry were used to investigate four consanguineous Pakistani families (A, B, C, and D) affected with ARCI. WES identified a frameshift mutation c.364dupA (p.T122IfsX3) in SDR9C7 in family A, a nonsense mutation c.762C>G (p.Tyr254*) in PNPLA1 in family B, a missense mutation c.944G>A (p.R315H) in TGM1 in family C, and a missense mutation c.424 (p.R142C) in TGM1 in family D. Mass spectrometry of purified proteins isolated from epidermal corneocytes samples of the affected individuals confirmed the deleterious effects of the identified mutations. Combinatorial protein analysis of the three groups (PNPLA1, SDR9C7, and TGM1) identified common 20 proteins with altered expression in all the disease groups indicating their central role in ARCI pathology. Furthermore, a proteomic spectrum specific for each type of ARCI was also acquired. In conclusion, four families affected with ARCI were identified with mutations in SDR9C7, PNPLA1, and TGM1 along with the proteomic profiles that could aid in the genetic counseling and prenatal diagnosis of the families as well as devising improved diagnostic and therapeutic approaches for ARCI.