جو دیپ پلکوں پہ دھر رہا تھا
وہ شب کا کشکول بھر رہا تھا
چہار سو نور تھا زمیں پر
کوئی فلک سے اتر رہا تھا
اُدھر بھی تو ایک زندگی ہے
وہ جی رہا ہے جو مر رہا تھا
ہوائے شب اشتعال میں تھی
چراغ جلنے سے ڈر رہا تھا
ہماری آنکھوں میں تشنگی تھی
کہ دل کا دریا اتر رہا تھا
سمیٹتا کیا وہ مجھ کو آ کر
جو خود ہی ہر پل بکھر رہا تھا
جو آ رہے ہیں شفیق آصف
میں یاد ان کو ہی کر تھا
Muslims are a unique nation in the world who have shown unparalleled activism in preserving their sayings and relics. Caution was in view from day one. The simple precautionary measures taken in the early days later took the form of theology. In the beginning, the principles and rules of this knowledge did not exist in a disciplined form, although the scholars of Muḥaddithin adhered to the basic principles of this knowledge from the very beginning. However, references to these principles were to be found in the books of the pious. In the 4th Hijri, the scholars of Muhaddithin compiled the previous scattered work on the art of the principle of Ḥadith. Now these comprehensive definitions and terms are before us in a systematic and disciplined form in the books of ‘Usūl e Ḥadīth. In this short essay, the definition and necessity and importance of Hadith and ‘Usūl e Ḥadīth have been highlighted and also an introductory review of books written on ‘Usūl e Ḥadīth th and their authors and authors has been presented. Which indicates this. How strict were the rules and regulations of the Muslim Ummah for examining the authenticity and text of the Holy Hadith and how did they separate the authentic, weak and subject matter of the hadiths and write their separate books? And how hard they have worked to promote art.
Asthma is an inflammatory chronic disorder of airways of lungs. In world, asthma is recognized as one of the most chronic diseases, which affects above 300 million people all round the world. In Pakistan, approximately 5-8% of adults are suffering from asthma. Both environmental and genetic factors contribute towards the development of disease. It is a multigenic disorder, and is due to different genetic factors, which also determine immune responses. The purpose of the present study is to identify and investigate polymorphisms in major asthma genes. In present study, 34 SNPs of 28 genes were genotyped by iPLEX and Taqman assay. HLA class II association was done by sequence specific PCR. It is found that the minor alleles of IL10 (rs1800896) and IL13 (rs1800925) are related to increased asthma risk in our population. It is also seen that the minor alleles of ADAM33 (rs2280091) are showing significant association with protection in Pakistani asthmatic population. ADAM33 minor allele is having protective effect in females. ACE homozygous insertion is reported to be associated with asthma risk in Pakistani population. HLA class II DRB1*07 and DQB1*03 are found to be important in asthma pathogenesis and DQB1*06 is showing statistically significant association with protection against the disease.