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Home > Effects of Dibutyl Phthalate As an Endocrine Disruptor on Growth, Glucose Homeostasis, Lipid Metabolism and Redox Status in Laboratory Animals

Effects of Dibutyl Phthalate As an Endocrine Disruptor on Growth, Glucose Homeostasis, Lipid Metabolism and Redox Status in Laboratory Animals

Thesis Info

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Author

Majeed, Khalid Abdul

Program

PhD

Institute

University of Veterinary and Animal Sciences

City

Lahore

Province

Punjab

Country

Pakistan

Thesis Completing Year

2018

Thesis Completion Status

Completed

Subject

Physiology

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/11134/1/Khalid%20Abdul%20Majeed_Physiology_2018_UVAS_PRR.pdf

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676724671372

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Dibutyl phthalate, a known endocrine disruptor, is a commonly used plasticizer that influences the glucose homeostasis. The present study elucidates the effects of dibutyl phthalate (1 and 5 mmol/L) on electrogenic sodium-linked glucose transport in the isolated rabbit ileum with ‘Ussing chamber.’ Serosal addition of dibutyl phthalate has no effect on glucose-based electrogenic changes in short circuit current, and no effect of dibutyl phthalate is observed on ileal tissue conductance and catalase activity. However, mucosal addition of dibutyl phthalate in the presence of glucose shows a trend of decrease in short circuit current compared with the control. This indicates that dibutyl phthalate may have a deleterious effect on the electrogenic intestinal glucose transport.
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تعلیمِ نسواں

تعلیم نسواں
علم جہاں پہنچتا ہے اندھیرے سے نکال کر روشنی میں لے جاتا ہے ،ظلمت سے ضیاء کی طرف روانگی ہو جاتی ہے، جہالت سے شعور وآگہی کا سفر شروع ہو جاتا ہے۔ علم ایک ایسی دولت ہے جو انسان کواوجِ ثرّیا تک پہنچا دیتی ہے۔ علم ایک ایسازینہ ہے جس سے معرفتِ الٰہی کے محل کی طرف رسائی ممکن ہے۔ علم کے زیور سے مرصعّ شخص معاشرے کے ماتھے کا جھومر ہوتے ہیں۔ علم کی حقیقتوں سے آشنائی ایک عظمت ہے اس طرح عورت علم کے زیور سے مزیّن ہوگی تو معاشرہ سنور جائے گا۔
مردوں کی بھی تعلیم ضروری تو ہے مگر
پڑھ جائے جو خاتون تو نسلیں سنوار دے
تعلیم نسواں سے مراد عورتوں کی تعلیم ہے۔ مردوں کی طرح عورتوں کے لیے بھی حصول علم بہت ضروری ہے۔ عورت اور مرد زندگی کی گاڑی کے دو پہیے ہیں۔ ان دونوں پہیوں کا صحیح ہونا بہت ضروری ہے۔ ورنہ زندگی کی گاڑی ٹھیک طرح سے چل نہ سکے گی۔ کوئی قوم اس وقت تک ترقی نہیں کرسکتی جب تک اس قوم کی عورتیں زیورِ تعلیم سے آراستہ نہ ہوں۔
نبی کریم صلی اللہ علیہ و آلہٖ وسلمکا ارشاد ہے کہ’’ علم حاصل کرنا ہر مسلمان مرد اور عورت پر فرض ہے۔‘‘ اس حدیث مبارکہ سے مرد اور عورت دونوں کی خاطر علم کی اہمیت واضح ہوتی ہے۔ آپ صلی اللہ علیہ و آلہٖ وسلمنے اپنی تعلیمات سے آگاہی کے لیے عورتوں کے لیے بھی ہفتے میں ایک دن مقرر کیا تھا۔ اس کے علاوہ ازواجِ مطہرات بھی عورتوں کو دین کی باتیں سکھایا کرتی تھیں۔ دانائوں کا قول ہے کہ’’ ایک مردکی تعلیم ایک فردکی تعلیم ہے، جبکہ ایک عورت کی تعلیم ایک خاندان کی تعلیم ہے‘‘ عورت کی آغوش ہی بچے کی پہلی درسگاہ ہے۔ یہ جو کچھ اپنی ماں...

A Review of Opinions of Scholars on Contemporary Issues and Future Plans for Interfaith Harmony

Interfaith harmony refers to the peaceful coexistence and cooperation between people of different religious beliefs. This abstract focuses on the need for interfaith harmony, the challenges that hinder it, and the way forward towards achieving it. The need for interfaith harmony arises from the diversity of religious beliefs and practices around the world, which can lead to misunderstanding, conflict, and violence. Interfaith harmony promotes mutual respect, understanding, and cooperation among people of different faiths, which can lead to a more peaceful and just society. However, achieving interfaith harmony is not without challenges. These challenges include ignorance, prejudice, fear, and mistrust among people of different faiths. There are also social, economic, and political factors that can contribute to the breakdown of interfaith relations. To overcome these challenges, there are several ways forward towards achieving interfaith harmony. These include education and awareness-raising initiatives that promote interfaith understanding and dialogue. There are also interfaith organizations that bring people of different faiths together for mutual cooperation and support. Additionally, there are political and legal measures that can protect the rights of religious minorities and ensure their full participation in society. In conclusion, interfaith harmony is essential for building a peaceful and just society. While there are challenges to achieving it, there are also ways forward towards promoting interfaith understanding, cooperation, and respect.

Location Based Sentiment Mapping of Topics Detected in Social Media

Social media has risen as a powerful social link among people. It gives them an easy, unsupervised, rapid and flexible platform for sharing information with each other. It serves like a virtual environment where there is no direct or indirect executive power to dictate their opinions. They feel free to appreciate or criticize the actions of others. That is why social media posts carry true reflection of public feelings over any social event. This very nature of social media content makes it a valuable asset for research community to dig deeper and find meaningful concerns out of its huge chunks. This research work explores how people across different regions of Pakistan think about any social media topic. The research work proposed a model to extract spatial, topical and sentimental information of social media posts and combine them together to perform location-based sentiment mapping of the topics detected in social media. The study area has been restricted to Pakistan.The research work started with collection of tweets using streaming API of the Twitter. The information contained in a 3rd party dataset worldCities was used to filter out Pakistani tweets and perform indirect conversion of user profile location into geo-location, as geo-location was directly not available with tweets. Probabilistic topic model; Latent Dirichlet Allocation (LDA) was used to extract latent topics from the dataset. CRAN library was used for sentiment classification of the tweets into 3 classes: positive, negative and neutral. The processed dataset was uploaded to a persistent storage Google Drive and then imported into a web based interactive self-written Shiny Application to read geo-spatial, topical and sentimental information of the tweets from processed dataset and produce interactive geographical map. The interactive geographical map has also been supported by heatmap, scatter plots, bar graphs and pie charts in order to enhance visualization process. The novelty of this research work is its location-based visualization of the strength of public opinion on any emerging event or topic in Pakistan.