المفتي: شروطه وآدابه

The duty of issuance Islamic legal verdict is a great job because the Mufti is the successor of the Prophets of Allah. He explains the commands of Allah — permissible and prohibited acts—and stops the disputes among the followers. The focal aspects of this research paper are the questions: What are the required conditions to be a reliable mufti? What are the points of agreement and differences among the four major schools of jurisprudence — Hanafi, Maliki, Shafa’i and Hanbali? The most important area of this paper is the question: What are the protocols and etiquettes of the procedure of issuance of a fatwa, the legal verdict, in our contemporary societies. In the first part of this paper, the analytical evaluation of the arguments presented by prominent jurists of the four major schools of Islamic Jurisprudence. This part suggests some points to reset the preferences because it is the need of time. The second part of the paper opines a number of suggestions to improve the manners, etiquettes and protocols of the procedure on part of a mufti. A mufti, being a representative of the seat of the Prophet (peace and blessings of Allah be upon him), is not only responsible to Allah Almighty but also to wellbeing, security, and peace among the members of our society.

Use of Magnetic Resonance Spectroscopy Mrs to Improve Magnetic Resonance Imaging Mri in the Diagnosis of Intracranial Pathology, Done at Aga Khan University

Introduction: Magnetic Resonance Spectroscopy (MRS)is a potentially useful adjunct to Magnetic Resonance Imaging (MRI) in thecharacterization of focal brain lesions. This study was aimed at showing that by the additional use of MRS (MRI, MRS), the characterization of a focal brain lesion into neoplastic, or non- neoplastic (infective, or degenerative) can be improved, as compared to the use of MRI alone. Study question: Does the additional use of MRS improve MRI differentiation of neoplastic from non- neoplastic (infective or degenerative) focal brain lesions? Methods: The design was prospective, analytical and comparative. 80 consecutive patients were enrolled. Conventional MRI of the brain was performed then a single voxel proton MRS spectrum was applied to a focal brain lesion. A similar MRS spectrum was subsequently acquired from the contra-lateral normal area of the brain, for comparison. The MRI examination, followed by the MRI, MRS examination was then interpreted by two consultant radiologists and a resident radiologist in consensus. Kappa measurement of agreement was used to determine the agreement between the MRI and MRI, MRS with the final diagnosis. Sensitivity, specificity, positive predictive values and accuracy of the two tests were calculated. The difference between the number of indeterminate lesions in the two tests was noted. Logistic regression demonstrated the role of confounding factors in the diagnostic use of MRS. Results: Of the eighty patients initially recruited, seventy four (92.5%) were analyzed, and six were lost to follow- up. According to the final diagnosis, 33% of the lesions were infections, 29% neoplastic, 37% degenerative and, 1% were indeterminate. On the basis of the kappa analysis, MRI, MRS had an increase in agreement of 7.4% compared to MRI and the confidence levels of the two tests did not overlap. The sensitivity of MRI, MRS was 4.82 times greater than that of MRI. MRI, MRS had a 1.7% increase in accuracy. The combined test reduced the indeterminate MRI lesions by 5.4%. Logistic regression showed that for lesions which were enhancing, MRS yield was more helpful if the voxel position included the enhancing part. Conclusion: The additional use of single voxel MRS improves the MRI characterization of neoplastic from non- neoplastic (infectious or degenerative) focal brain lesions. It is most useful as an additional protocol to conventional MRI in the characterization of neoplastic from non- neoplastic brain lesions.