موضوع 5:زبان اور بولی میں فرق
زبان:
زبان خیالات و احساسات کا ذریعہ اظہار ہے۔جذبات و احساسات کی شکل زبان ہے اس کا کام لفظوں اور فقروں کے توسط سے ان کے ذہنی مفہوم و دلائل اور ان کے عام خیالات کی ترجمانی کرنا ہے۔زبان بولیوں کے مجموعے کا نام ہے۔
بولی :
بولی کسی زبان کی وہ ذیلی شاخ ہے جس کے بولنے والوں کو زبان کے کسی اختلاف کا احساس نہیں ہوتا البتہ کسی زبان کی ایک بولی بولنے والوں کو اسی زبان کی دوسری بولی کے تلفظ کے فرق کا احساس ہوتا ہے۔ہر زبان کا ہر بولی کا مخصوص انداز ہوتا ہے زبان چشمے کی حیثیت رکھتی ہے اور بولی اس سے پھوٹنے والی نہریں۔بولی ایک ایسی زبان ہے جو کسی علاقے میں رائج ہوتی ہے اس کی کوئی ادبی حیثیت نہیں ہوتی۔ زبان جس قدر وسیع ہو گی اس کی بولیاں بھی اسی قدر وسیع ہو گی۔ بولی عام فہم زبان ہے جو ہم مقامی لوگوں سے سیکھتے ہیں ایک بولی بولنے والے عام طور پر ایک زبان استعمال کرتے ہیں ہر علاقے کی بولی کا مخصوص انداز ہوتا ہے۔
تلفظ کا اختلاف:
بولی قواعد و ضوابط سے آزاد ہوتی ہے بولیوں میں لفظ کی ادائیگی میں اختلاف پایا جاتا ہے مختلف علاقوں میں مختلف بولیاں بولی جاتی ہیں۔بعض بولیاں ترقی کرکے زبان کا منصب حاصل کر لیتی ہے اور بعض جگہوں پر صرف بولی بن کر رہ جاتی ہے۔ ہمارے ملک میں قبائلی علاقے ہیں جو غیر متمدن ہیں وہاں نقل مکانی کے مواقع کم ہوتے ہیں ان کے تلفظ میں اختلاف پایا جاتا ہے۔
زبان کا نظام:
ہر زبان اپنا نظام رکھتی ہے۔ یہ مختلف عناصر پر مشتمل ہوتا ہے۔ اس کے قواعد و ضوابط ہوتے ہیں مثلا صرف و نحو اس میں وقت کے ساتھ ساتھ تبدیلیاں آتی رہتی ہیں۔...
Marriage has been given the status of half-faith, based on which a family is formed, and society is established. Marriage is associated with issues of lineage and inheritance and a section of the Quran describes this subject. The jurists have explained in detail the issues of marriage, dowry, breastfeeding, 'iddah, and alimony under the book of marriage. Ibn Taymiyyah, like other jurisprudential issues, has differed from several jurists on issues related to marriage. For example, it is fair for a man to marry his wife's foster mother and foster daughter. Marriage can take place in any of the terms or words from which the meaning of marriage is derived. Like the father, the grandfather also has the right to marry a minor girl without her permission, it is permissible to marry, the wife has the right to terminate the marriage in case of defect in Haq-e-Mahr, etc. All such jurisprudential dissent will be explained with arguments so that one can be aware of Ibn Taymiyyah's dissent and the arguments behind it.
KeyWords: Ibn e Taymiyyah, Jurisprudential Distinctions, Nikaḥ, Kitāb un-Nikaḥ Haq-e-Mahr.
Poor oral bioavailability is a major challenge affecting the new drugs reaching the market due to its low aqueous solubility. Nanocrystals have the potential and rapidly providing a platform solution to substantially increase dissolution rate, solubility with subsequent enhanced bioavailability and effectiveness via the oral route of administration of a range of poor water soluble drugs. The current study is comprised on two parts utilized antimalarial drugs: the first part was comprised on fabrication of artemether (ARTM) and lumefantrine (LMF) nanoparticles using a novel top down wet milling approach (DENA DM-100) and in the second part: cost effective simplest approach of re-precipitation combined with ultrasonication was utilized for fabrication of artemisinin (ART) nanoparticles with the aims to enhance their dissolution and hence the bioavailability of these antimalarial drugs. Smart nanocrystals of artemether (ARTM) and lumefantrine (LMF) were fabricated in the form of nanosuspensions in shortest milling time (less than 1 hr) in both aqueous and acidic medium using a novel wet milling technology (DENA DM-100). Both high feedstock concentration (10% w/w) and low feedstock concentration (2.5% w/w) of ARTM and LMF yielded nanocrystals with maximum recovery of the active contents. Similarly, we revisited the simplest approach of re-precipitation combined with ultrasonication for fabrication of artemisinin nanoparticles in the form nanosuspensions. Different critical parameters, including the effect of different concentrations of stabilizers, temperature as well as optimum parameters/conditions were identified, which was found to be very critical not only for fabrication as well as for scale up of the batch size, which is critical issue associated with this approach. xii Additionally, the physical stability studies of artemether, lumefantrine and artemisinin were conducted for 90 days at different storage temperatures demonstrated that nanocrystals stored at 2-8°C and 25°C were most stable compared to the samples stored at 40°C. There was not observed any chemical degradation in the APIs during the chemical stability studies which was monitored for 07 days. Similarly artemether, lumefantrine and artemisinin nanocrystals were produced in the size ranges of 161±1.5 nm and 214.1±1.2 nm, 98.77±1.5 nm respectively, where they showed significantly enhanced solubility, dissolution rate and enhanced antimalarial efficacy (in vitro and in vivo) compared to its unprocessed, micronized, microsuspension and their marketed counterparts in relatively low dose. In summary the study demonstrates that both novel top down DENA (DM-100) technology and standard crystallization combined with ultrasonication are effective in producing stable nanocrystals with smallest particle sizes, increased saturation solubility and enhanced dissolution rate with enhanced in vitro and in vivo antimalarial activities while controlling the key experimental and process conditions.