It is said that 21st century will be the century of Asia. The South Asia, particularly, is often quoted in the political and academic circles of the West as one of the world’s highly sensitive conflictual regions. There is now a larger consensus that Asia’s importance has grown manifold in the global arena. Obviously, it plays a strategic and more assertive role in both regional and global politics. Its economic and strategic environment has substantially transformed particularly in the last decade. And this process is likely to unfold even more vigorously for several decades to come, contributing to its dynamic strength. As an emerging powers China and India are very important in this region. Pakistan relations with them are the main concern of the researcher and policy makers of Pakistan. In many turns of the history, changing Geo-politics have effected the triangular relations of these three countries. Their policies are also affected by the involvement of big powers in the region. In Asia, Pakistan-China-India is an important triangle, having complicated relationship with each other. The interlinked policies of all the three countries shaped the security environment of the region. A policy adopted by one country has immediate impact on the other two countries of the triangle and they responded accordingly. This thesis mainly discusses the history of Pak-China-India relations, the geo-political change in post cold war and post 9/11 and their changing policies according to the change circumstances regionally and globally. Also focus on their future prospects that how their relation will turn in future, could they will be able to solve their mutual disputes, whether they will integrate economically and politically by having friendly relations or vice versa. This is the time of fittest, those will survive who will fit. This thesis also discusses that in this most competitive environment effective policy options for Pakistan, that how she can use her relations for best serving her national interests.