This study was conducted to study the prediction of distance learners’ achievements from locus of control and self-efficacy at post graduate level. The study aimed to predict the achievements from locus of control and self-efficacy. Population of the study comprised of students (Spring/Autumn 2015) of teacher education programs (M.A, M.Ed and B.Ed) through distance learning mode. Sample of 1513 distance learners (for quantitative analysis) was drawn out through disproportionate stratified random technique. Out of this sample, 5% (38 females and 38 males) respondents were randomly selected for semi-structured interviews.Two standardized instruments (Nowicki and Duke Locus of Scale, and General Self-efficacy scale) were adapted. Two interview guides were developed by the researcher. Achievements were measured in terms of students’ grades in the semester (Spring/Autumn 2015), life success/distinctions, and co curricular activities. Major findings of the study revealed that distance learners with internal LOC and high SE predicted high achievements and distance learners with external LOC and low SE exhibit low achievements. Significant positive relationships between SE, LOC and achievements of DLs emphasizes the importance of these variables. In this regard, training programs for course developers may be organized in a way that these may help them to focus on the importance of psychological variables in during course development. The correlation between internal LOC and high achievements also emphasizes the need that distance learners may have knowledge regarding the importance of psychological factors which play significant role in achievements. In this regard, the arrangement of end of semester reflective exercises may help DLs to gain knowledge about their LOC. Prediction of DLs achievements from LOC and SE also provoked the importance of the variables of this study for the authorities of distance education universities to pay attention towards the enclosure of psychological factors in curriculum i.e. inclusion of problem solving activities at the end of self assessment exercises, and graded problem solving projects/tasks may prove helpful.