70. Al-M’arij/The Ascensions
I/We begin by the Blessed Name of Allah
The Immensely Merciful to all, The Infinitely Compassionate to everyone.
70:01
a. A disbelieving questioner mockingly asked The Prophet about the punishment in the realm of the Hereafter which is bound to befall -
70:02
a. – the disbelievers.
b. And no one can prevent the coming of it -
70:03
a. as it is coming from Allah.
b. And, Allah is Rabb - The Lord - The Lord of the Ascensions.
70:04
a. Ascensions to where the angels and the spirit take a day to ascend,
b. where duration of a day would be equivalent to fifty thousand years of your count.
70:05
a. So O The Prophet!
b. Be patient with a gracious patience.
70:06
a. They perceive this punishment to be far away,
70:07
a. while WE see it as quite near at hand as an inevitable reality -
70:08
a. it will befall at the Time when the celestial realm will be like molten copper,
70:09
a. and the mountains will be floating about in the air like flakes of wool/yarn,
70:10
a. and no close friend will ask any other close friend about his fate,
b. for everyone will be preoccupied with his own predicament -
70:11
a. even though they could see one another.
b. The criminal would wish to ransom himself from the inevitable punishment of that Time by
offering his own children,
70:12
a. and even his spouse and his brother/siblings,
70:13
a. and his relatives...
All the Prophets have been respectable in the scriptures of all the world religioins. They were sent to this world for a significant cause and remained model role for human beings, especially in Islamic point of view they have been a part of belief; and any disgrace towards them is regarded an act of pegamism. In modern ages the concept of presenting the lives of the prophets in film stories is developing though it is a source of knowledge but for many reasons it held a sign of interrogation wich has been discussed in this Article.
The stability constants of gatifloxacin-metal complexes have been studied potentiometrically. The stability constant of the gatifloxacin metal complexes were calculated using a potentiometric method.For this purpose potentiometric data were computed through PSEQUAD Software. Stoichiometry of the complexes was calculated by Job’s method and mole ratio at different pH ranging from 4 to 9.During the stoichiometric determination of gatifloxacin-metal complexes at different pH, 1:1 ratio of metal to ligand at lower pH and 1:2 ratio of metal to ligand at higher pH were employed. For thermodynamic parameters like ∆?, ∆? and ∆? of gatifloxacin metal complexes were determined by pH titration at different temperatures (i.e. 30 ºC, 35 ºC, 40 ºC, 45 ºC and 50 ºC). The pH titration data were used for calculation of ???? values by PSEQUAD computer program. Graphs were plotted for ??? versus 1/?.The slope of this graph represents (−∆?/?) and the intercept is (∆?/?).The changes in ???? values at different temperatures were examined and enthalpy and entropy values were determined for ML and ML2 of gatifloxacin complexes. Gatifloxacin and moxifloxacin complexes were synthesized with different metal ions including Mg(II), Al(III), Ca(II), Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II) and their structures were determined by spectrophtometric techniques like UV and IR. Stability studies of gatifloxacin and moxifloxacin were carried out under accelerated and long term conditions.Thermo lab stability chamber model T90008008 was used for that purpose. For accelerated stability studies, gatifloxacin and moxifloxacin were kept at 40 °C ± 2 °C at humidity RH 75% ± 5% and nil intensity of light (illuminate degree) was applied for six months.For long term stability conditions, at 30 °C ± 2 °C, humidity RH 70% ± 5% and nil intensity of light (illuminate degree) was applied for 12 months. No significant changed were observed on gatifloxacin under accelerated and long term conditions. In order to monitor the stability studies, the HPLC and spectrophotometric methods were developed as per ICH guide line. IR spectra were also obtained for identification of gatifloxacin and moxifloxacin were during stability studies. xix In-vitro biological activities (antibacterial and antifungal) of gatifloxacin and moxifloxacin and their metal complexes were performed.It was found that the metal complexes are more active as compared to gatifloxacin and moxifloxacin.