Knowledge of science produce a great impact on our life style, way of thinking, and our behavior etc. a great change occurs in our outlook because of the influences, of scientific knowledge. Science has revolutionized the civilization. Science teaching is a most difficult task and everybody is not fit to be teacher, some person may have a flair for teaching and such person have the ability to awaken interest and catch the attention of the students. Hence teaching of science is an art of assisting another person to learn. The aims of teaching of science at the college level is to develop scientific attitude ,enhance the scientific and technological competence, encourage creativity and solve the problems confronted by the students in their day to day life both within and outside the college premises. Therefore the science teacher needs to know about the variety of learning approaches and use technology while teaching. The overall purpose of the study was to analyze teachers ‘competencies and teaching practices of Physics subject teachers at higher secondary level in Sindh. The study specifically analyzed the knowledge, skills, and behaviors of the Physics teachers with relation to subject command and implementation. The scope of study was limited to the college principals, teachers, students, and curriculum experts in the province of Sindh. Eight hypotheses were formulated and mixed research technique was adopted. All the principals’ Physics teachers and science students, were part of population .The population is large and heterogeneous therefore the stratified random sampling design was used. The questionnaires, interview protocols and observation checklist were the major instrument. Data was collected through the personal visits and analyzed by using inferential statistical technique along with the content analysis of the data. Concrete recommendations were made on the basis of findings.