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Home > Antiglycation and Antioxidant Activities of Some Desert Plants.

Antiglycation and Antioxidant Activities of Some Desert Plants.

Thesis Info

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Author

Nazneen, Fariha

Program

PhD

Institute

University of Agriculture

City

Faisalabad

Province

Punjab

Country

Pakistan

Thesis Completing Year

2016

Thesis Completion Status

Completed

Subject

Biochemistry

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/9605/1/Fariha_Nazneen_Biochemistry_UAF_2016_10.06.2016.doc

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676725508536

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Traditional uses of plants have been found since the time of antiquity. Their medicinal use has got attention of modern day researchers due to easy availability, less cost and negligible side effects.Sustained hyperglycemia causing diabetes and its complication is implicated by free radicals and AGEs leading to oxidative stress, damages different cell components. In the present study desert plants of Cholistan were selected including Boerhavia repens, Cleome brachycarpa vahl.ex.DC, Cymbopogon jawarancusa, Dipterygium glaucum, Prosopis cineraria and Fagonia indica as these were found to be unexplored. Preliminary phytochemical screening exhibited strong presence of saponins, steroids and alkaloids except C. brachycarpa vahl.ex.DC. P. cineraria and C. jawarancusa showed considerable presence of flavonoids which was further confirmed by quantitative analysis of plants for crude flavonoids contents. Saponins were found to be maximum for F. indica and alkaloids in C. jawarancusa. Extract yield (%) was found to be maximum for D. glaucum aqueous extract and P. cineraria methanolic extract. Highest amount of total phenolics were found in F. indica aqueous extract and P. cineraria methanolic extract. When antioxidant activities were determined by reducing power assay, maximum activity was shown by aqueous extract of P. cineraria and F. indica methanolic extract expressed as mmol of AAE/g dw of extract. Aqueous and methanolic extract were analyzed for inhibition of lipid peroxidation in linoleic acid system and maximum activity was shown by F. indica aqueous as well as methanolic extractat maximum concentration. EC50 was calculated and aqueous extract of C. jawarancusa was most effective while methanolic extract of F. indica was found to be more potent antioxidant. Significant inhibition of free radical scavenging by DPPH method was exhibited for all plant extract with maximum value for F. indica aqueous extract and minimum by B. repens .Whereas methanolic extract of P. cineraria exerted maximum inhibition and it was also found to be most effective when EC50 was calculated. All these methods were performed to have a comprehensive over view of plants antioxidant activities. Rate of glycation was found to be increasing with increasing temperature. Glycation level quantification by TBA method and all tested plants were reported for maximum glycation level at first week of incubation. P. cineraria methanolic extract was noted for maximum inhibition of glycation and D. glaucum for minimum response at 37°C. At 50°C P. cineraria and F. indica were reported for minimum glycation level at 2nd week of incubation. Appreciable inhibition was observed by P. cineraria, C. jawarancusa and C. brachycarpa vahl ex DC at third week of incubation and minimum glycation inhibition was exerted by F. indica. All plants were found to be considerable antioxidant and antiglycation agent but P. cineraria and F. indica conferred highest antioxidant and antiglycation activities. The potential for these activities may be explained in term of high total phenolic contents, flavonoid contents and rich saponins of F. indica attributing towards medicinal properties.
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جاڑے کا موسم

جاڑے کا موسم

جاڑے کا موسم حیرت سے
میرا منہ تکتا رہتا ہے

کیسے اُس کی لمبی راتیں
کیسے اُس کی ٹھنڈی راتیں
میں تنہا ہی کاٹ رہا ہوں

وہ کیا جانے میرے دل کو
میں اُس کی لمبی راتوں میں
میں اُس کی ٹھنڈی راتوں میں
بھول کے چاند بھی جاڑے کا میں
کمرے اندر بیٹھ کے بس میں
یاد تمہیں کرتا رہتا ہوں

جاڑے کا موسم حیرت سے
میرا منہ تکتا رہتا ہے

Analytical Study of Dual Banking and Earlier Efforts Towards Islamization of Bank of Khyber in the Light of Shariah

The proposal of interest-free banking is very old because Islam restricted the interest base transaction at very beginning after the revelation of prohibition of Interest, noble Quran called it as Riba. This prohibition is of sever nature relatively, Allah says; O you who have believed, fear Allah and give up what remains [due to you] of interest, if you should be believers. And if you do not, then be informed of a war [against you] from Allah and His Messenger. The suggestion for the establishment of such financial institutions that run according to shariah has been put in queue for about centuries. To get rid from the dominancy of conventional banking system, forced the religious scholar to take initiative in this regard and started interest free banking. It was not easy to switch entirely from conventional banking system to Islamic one as for different technical issues, leads the existent banks to start dual banking system. Bank of Khyber is the first Bank of Khyber Pakhtunkhwa operating as dual banking, i.e. Conventional as well as Interest free banking. This study focuses on analysis of dual banking system of bank of KHYBER in order to know the extent of conformity with shariah standards along with highlighting the earlier efforts of it towards Islamization.  

Puritan Shift: Evolution of Ahl-I-Hadith Sect in the Punjab a Discursive Study 1880-1947

This study focuses on the puritanical impact of Ahl-i-Hadith revivalist movement on the transition of the Sufi ethos of the Punjab during the late nineteenth and first half of the twentieth century. One can define Shrine-centered Islamic tradition as a defining feature of the Sufi ethos in the Punjab during the medieval period (11th-18th centuries). The Sufi ethos constitutes equality, social justice, Suleh Kul, Wahdat-ul-Wajud ideology, and accommodationist vision. All these factors of the Sufi tradition of the Punjab created pluralistic outlook among the masses. This tradition left indelible imprints on the local culture, particularly imparting values like tolerance, humanism, and social equality. The growth of Shrine-centered Islam in the Punjab was a reaction against the social stratification solidified by the caste system which became more rigid with the passage of time. The origin of this tradition dates back to Vedantic tradition, however, its contours were further sharpened when Ibn Arabi’s (1165-1240) Wajudi ideas permeated in the philosophical discourse of sufis in the subcontinent. In Punjab, Baba Farid Ganj Shakar (1175-1265) emerged as the main exponent of this philosophy. The reform movement of Ahl-i-Hadith ultimately questioned this strong Sufi tradition since later half of the nineteenth century. The study deals with the subsequent religious transition of a reasonable segment of the Punjabi Muslims. It concentrates on the particular aspects of Ahl-i-Hadith Movement i.e.; emphasis on scriptural Islam, direct recourse to Quran and Hadith, opposition to the prevailing four schools of Islamic Jurisprudence, rejection of all sufi forms of Islam (muharram, urs, qawwāli, gyārahwin of Abdul Qadir Jillani, pilgrimage to the graves of the Prophets and saints, majlis-i-milād (birth anniversary of Holy Prophet), simah-i-maota (listening of the dead) and observance of various ceremonies associated with death rites, i.e. Qul sharif, Satavan (seventh day ceremony after death) and Chaliswan (ceremony on the fortieth day after death). Rejection of contemplation and attempts to expunge Sufism remained the hallmark of this movement as they emphasized on this worldly responsibilities of the Muslims rather than out-worldly asceticism (denial of this world and bodily contemplation) of the Sufis. They through the establishment of their own religious seminaries in the cities and towns of the Punjab and engaging in munāzara tradition with non-Muslims (Arya Samajis, Christian missionaries,) and Muslim sects (Shias, Barelvis, Deobandis, and Ahmadis) were able to draw a certain segment of the Muslim population towards them. Moreover, this study seeks to establish a connection between the contestation of puritanical Ahl-i-Hadith Movement with the colonial modernity; such as the western type of education and Missionary Agency, translation of scriptures into local languages and technology of printing. This agency of modernity helped in solidifying the literal interpretation of the Quran and Hadith that was the main feature of the Ahli-Hadith Movement. By emphasizing this aspect, I do not suggest that this contestation led Ahl-i-Hadith Movement to re-conciliate with modernity rather it highlights how this Movement made use of various tools of modernity for the dissemination of its puritanical teachings. The Ahl-i-Hadith Movement tried it best to adopt those features of the Colonial modernity that helped them in the dissemination of their ideas far and wide of the country. This movement was primarily sprouted from Delhi and spread throughout India and hence in the Punjab. The scholars of this movement stood for the cause of Islam declared the Sufi practices as innovations and created a reasonable following. This thesis attempts to formulate a new and comprehensive analysis of the Ahl-i-Hadith movement.