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Home > Comparison Between Diabetic Patients and Hepatitis B and C by Clinical Metabolic Investigations

Comparison Between Diabetic Patients and Hepatitis B and C by Clinical Metabolic Investigations

Thesis Info

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Author

Mastoi, Abdul Aziz

Program

PhD

Institute

University of Sindh

City

Jamshoro

Province

Sindh

Country

Pakistan

Thesis Completing Year

2012

Thesis Completion Status

Completed

Subject

Chemistry

Language

English

Link

http://prr.hec.gov.pk/jspui/handle/123456789/867

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676725770084

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In Diabetic syndrome, function of heart and liver are commonly affected, causing the worsening of these patients and hence, additional drugs apart from diabetic treatment are given to these patients. However, these drugs cause additional complication promoting many side effects. This thesis is composed of determining the metabolic abnormalities in the diabetic patients with the complications of hypertension and liver cirrhosis. In addition this study is furthered on diabetic patients with hepatitis B or C. In all these patients, the association of most important blood enzymes, such as (1) aspartate aminotransferase (AST) or, (2) Serum Oxaloacetate Transaminase (SGOT), (3) alanine aminotransferase (ALT) or (4) Serum Glutamate Pyruvate Transaminase (SGPT), (5) creatinine phosphokinase (CPK), (6) lactate dehydrogenase (LDH) and (7) alkaline Phosphatase (ALP) are studied. Some of the most important metals such as iron, zinc, copper and magnesium and their overall impact on oxidative stress are also determined. My hypothesis in diabetic patients a complete picture of metabolic abnormalities could be obtained, if enzymes conventionally with liver, and heart dysfunction, are studies, total protein, albumin, creatinine, urea, uric acid, total cholesterol, and triglyceride levels are monitored; the role and anti oxidant activity of magnesium, zinc, copper is studied. This study was conducted one diabetes mellitus, hypertension, liver cirrhosis, diabetes with hypertension, diabetes with liver cirrhosis hepatitis B, hepatitis C, diabetes with hepatitis B, and diabetes with hepatitis C,. The purpose of my study is to see the changes in enzyme activities related to metabolism and the variation in metal contents with particular reference to Fe, Cu, Zn and Mg including the ant oxidative activity in diabetic patients with and without complications. This will assist the pharmacists to design a new chemotherapeutic, drugs, and for the physicians, to treat the patients with different complications effectively.
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حرف آغاز

ڈاکٹر نصیر احمد اسد کی تصنیف’’ ارضِ اقبال آ فاقیت کے آ ئینے میں‘‘ کے مقالات جہاں ان کے تحقیقی ذوق کے آ ئینہ دار ہیں وہیں ان کی تنقیدی بصیرت کے بھی گواہ ہیں۔ انہوں نے بنیادی مآخذ سے استفادہ کرتے ہوئے زیر نظر موضوعات کا نہایت تفصیل کے ساتھ جائزہ لیا ہے ۔
     ایک بہت بڑی خوبی جو ان مضامین میں از اوّل تا آ خر موجود ہے وہ یہ کہ اُنہوں نے محض مشاہیر ادب و تحقیق کی آ را اور فیصلوں کو نقل نہیں کیا بلکہ اپنا نقطہ نظر پیش کیا ہے۔ ان کا یہ طالب علمانہ انداز ان کے ان مضامین کو انفرادی رنگ کا حامل بناتا ہے۔ تاہم یہ کم خوبی کی بات نہیں کہ زیر نظر موضوع پر ریسرچ سکالرز کا اپنا نقطہ نظر سامنے آ تا ہے۔ان مضامین میں حواشی ،حوالہ جات اور تعلیقات کا خاص خیال رکھا گیا ہے۔ اس کے علاوہ مواد ، زبان و بیان اور پیش کش کے اعتبار سے یہ مضامین لائق مطالعہ اور قابلِ تحسین ہیں ۔
    تحقیقی وتنقیدی دنیا میں ڈاکٹر نصیر احمد اسد پہلی بار ’’ارضِ اقبال آفاقیت کے آ ئینے میں‘‘ کے ساتھ داخل ہو رہا ہے۔ ان کی یہ تازہ کاری،ذوق و شوق اور سعی و کاوش خوش آئند ہے۔ان کے علمی انہماک اور وفور شوق کے باعث امید کی جا سکتی ہے کہ وہ آ ئندہ میدان ادب و تحقیق میں اپنے کام کے معیار کو مزید بلندیوں سے ہم کنار کریں گے۔
ڈاکٹر یوسف خشک
چئیر مین اکادمی ادبیات اسلام آباد ، پاکستان

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