Search or add a thesis

Advanced Search (Beta)
Home > Correlation Between Toxoplasmosis and Some Endocrine Parameters for the Assessment of Immunopathogenic Mechanisms of Human Population

Correlation Between Toxoplasmosis and Some Endocrine Parameters for the Assessment of Immunopathogenic Mechanisms of Human Population

Thesis Info

Access Option

External Link

Author

Mateen Arshad

Program

PhD

Institute

Lahore College for Women University

City

Lahore

Province

Punjab

Country

Pakistan

Thesis Completing Year

2018

Thesis Completion Status

Completed

Subject

Biological & Medical Sciences

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/10826/1/Mateen%20Arshad_Zoology_2018_LCWU_PRR.pdf

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676725794799

Asian Research Index Whatsapp Chanel
Asian Research Index Whatsapp Chanel

Join our Whatsapp Channel to get regular updates.

Similar


Present study deals with the correlation of Toxoplasma with some endocrine parameters for the assessment of immunopathogenic mechanism in human population selected from different localities of Lahore. Besides analysis of blood using ELISA for various parameters (anti-Toxo IgG and IgM, Insulin, TSH, T3, T4, FSH, LH, testosterone and estradiol) this multidisciplinary study involved the questionnaire survey of the area for the assessment of health status of the study respondents and risk factors regarding toxoplasmosis. Data was analyzed statistically by Chi-square test, ttest, ANOVA and correlation (p<0.05). Analysis of data revealed that seroprevalence of Toxoplasma infection was significantly related to various factors; socioeconomic status, pica habits, consumption of untreated water for drinking purpose and exposure to oocysts contaminated surfaces as feral cats have high abundance in the study areas. Toxoplasma gondii infection was highly prevalent among study subjects. It was found that chronic Toxoplasma infection was more prevalent (58.5%) among respondents then acute/recent cases (41.5%). Gender wise comparison showed that prevalence of infection was higher among male subjects (86%) in compared to the females (34%). Percentage prevalence of Toxoplasma had positive correlation with seropositivity among subjects of 36-44+ years of age. Toxoplasma infection was found to be correlated with different endocrine hormones. Higher insulin concentration was detected among seropositive subjects reflecting similar trend in both sexes. The deviation was significant among senior age groups. The concentration of TSH, T3 and T4 was detected to be higher than the reference value among 9%, 19% and 79% subjects respectively. In case of male seropositive subjects, LH was significantly higher (11.89±0.66mlU/ml) whereas testosterone was found to be lower (2.82±0.13ng/ml) than normal reference value. In general female Toxoplasma positive respondents were detected with variable ranges of FSH, LH and estradiol during various reproductive phases. These changes in various hormones reflect the possible role of toxoplasmosis leading to various metabolic disorders and reproductive problems. The results are depictive of the fact that lack of education and awareness, poor hygiene conditions and other risk factors greatly enhance the transmission of such parasites. The results of the study are significant and provide enough evidence regarding toxoplasmosis and its correlation with the changes in various hormones leading to health effects.
Loading...
Loading...

Similar Books

Loading...

Similar Chapters

Loading...

Similar News

Loading...

Similar Articles

Loading...

Similar Article Headings

Loading...

مقاطعہ قریش

مقاطعہ قریش
رفتہ رفتہ مسلمانوں کی تعداد میں اضافہ ہوتا گیا چند نفوس قدسیہ حضرت عمر ؓ اور حضرت حمزہ ؓ جیسے جری ، نڈر، صائب الرائے اور پختہ عزم و عقیدہ کے مالک تھے ۔ یہ نامور اور شہرت یافتہ لوگ تھے یہ بنیادی حیثیت رکھتے تھے ۔ ہمالیہ پہاڑ کااپنی جگہ سے ٹل جانا ممکن تھا لیکن ان کا اپنے موقف سے ہٹ جانا نا ممکن تھا ۔ صحابہ کرام کو جس قدر تشدد کا نشانہ بنایا کفار کو منہ کی کھانا پڑی اور جتنی شدت سے نا روا ظلم اور بہیمانہ سلوک روا رکھا گیا وہ اسی قدر نا کام اور نا مراد ہوئے ۔ کفار کے عزیز و اقارب ایک ایک کر کے اسلام قبول کر رہے تھے ۔ کلمہ حق کی صدا بلند کرنے اور اسلام کو سینے سے لگانے میں جو کچھ مسلمانوں پر بیتی اس کے تصور سے انسان لرزہ بر اندام ہو جاتا ہے ۔صحابہ کرام کے بجز حضور ﷺ بھی قریش کی ایذاء رسانیوں سے محفوظ نہ تھے کفار کے تیار شدہ (ready made ) اور آموختہ بچے آپ ﷺ پر پتھر برساتے اور گالیاں بکتے ، کبھی مجنون و ساحر اور کبھی کاہن و شاعر کہہ کر تمسخر اڑاتے ، آپ ﷺ پر کوڑا کرکٹ پھینکا جاتا ، اونٹ کی اوجھڑی آپ ﷺ کی پشت پر حالت نماز میں ڈال دیتے بعض دشمن راہ میں کانٹے بیچھاتے حتی کہ طائف میں انسانیت سوز ظلم کیا آوارہ لڑکوں کو پیچھے لگایا وہ آوازیں کستے ، پتھر پھینکتے جس سے آپ ﷺ لہو لہان ہو گئے اور خون سے جوتے بھر گئے۔ کسی نے چادر گلے میں ڈال کر بل کس دئیے کہ آنکھیں باہر نکل آئیں ۔اسلام سے بر گشتہ کرنے کے لیے دنیا بھر کے جتن کیے ۔ جب ہر حربہ اور ظلم و ستم میں بجھا...

حضرت مولانا عبد الغنی ’’حاجی صاحب‘‘ کا تعارف و خدمات

Allah has created this universe and for guidance of people he has sent his different holy books and with those books he has sent different holy messengers. The messengers of Allah came to this world and preached the message was written in his books. When his messengers completed their job then their duty was given to the scholars of Islam. They also preached Islam from place to place and they face many difficulties and hardships but they continue their message. Among all these scholars some of them worked hard for writing and teaching the holy Quran to other people. Molana Abdul Ghani is one of these scholars who spent all of his time to serve Islam and preaching of Islamic thoughts. In this paper will present the Services and Introduction of Molana Haji Abdul Ghani.

Evaluating the Impact of Refactoring on Clients and Unit Tests

Refactorings are specific code transformations that improve the design of existing code without changing its externally observable behavior. In practice, unit tests are the most commonly used tools to ensure preservation of behavior after refactoring. Since unit tests are tightly coupled with the code, refactoring of the code can also invalidate the associated unit tests. If not properly adapted and maintained along with any transformation in the production code, the safety net provided by the unit tests would not be available and could result in a huge loss in terms of effort and cost. Refactoring guidelines provide mechanics for code transformation and refactoring tools provide support for automatic execution of these mechanics. Since refactoring can result in breaking of client and test code, adaptation techniques to fix these should be appropriately addressed. This thesis extends the state of the art in refactoring by formalizing the concept of unit test adaptation with refactorings. In this thesis, we established that, in the context of refactoring, unit test is different from an ordinary client. Therefore, it requires additional adaptations that are not applicable to any other client in the software. For instance, moving a method to another class requires adaptation of its clients including the unit tests. If the clients are not updated, this refactoring will result in compilation errors. On the other hand if test code is not adapted accordingly, this refactoring will introduce test smells in the test code. The test adaptation mechanics developed in this thesis also improve the design of test code along overall improvement in quality of production code. In this thesis we reviewed and analyzed various concepts and tools for refactoring java programs. and unit testing and identified the areas that could be improved. It also includes identification of problem areas in Fowler’s catalog via empirical evaluation . It has also been demonstrated, how refactoring guidelines can be extended. In addition, a test and client adaptation framework has been designed. This framework can provide a basis for automation of primitive refactorings and their associative adaptive actions to be performed on production and test code. The functions from this framework have been used to develop formal specifications of extended refactoring guidelines at different levels of abstraction. We also show with the help of results from an expert survey, empirical investigation and practical demonstration that our proposed approach has various advantages as compared to conventional approaches.