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Home > Determination of Banned Aromatic Amines in Consumer Goods: A Greener Approach

Determination of Banned Aromatic Amines in Consumer Goods: A Greener Approach

Thesis Info

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Author

Dewani, Rajkumar

Program

PhD

Institute

University of Karachi

City

Karachi

Province

Sindh

Country

Pakistan

Thesis Completing Year

2018

Thesis Completion Status

Completed

Subject

Chemistry

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/12391/1/Rajkumar_chemistry_uok_2018_PRR.pdf

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676725839662

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Banned aromatic amines due to their acute toxicity in human and animals hold key importance. Certain azo dyes have the tendency to release these banned amine intermediates upon cleavage of azo bond(s), even when present in a dyed materials. The tendency of four selected azo dyes (acid red 1, direct red 28, direct blue 15 and direct red 7) to release harmful aromatic amines is analysed by the standard test methods for colorants, dyed leathers and textiles (cotton, linen, wool, nylon). The basic steps of these tests methods are similar comprising of reduction, extraction and detection by instrumental techniques. The standard method for colorants was modified for UV-visible spectroscopy in initial exploration so that a quick inference could be generated. Methods based on sophisticated techniques (e.g., GC-MS and HPLC-DAD) were used in advanced steps. Conventional reduction methods were modified using ultrasound (UAR) and microwave assisted reductions (MAR) as greener techniques. UAR experiments were additionally extended with variations of temperature and exposure time. Direct dyes were applied onto leather, wool, linen, and cotton whereas the acid dye was applied to leather, wool, and nylon (due to substantivity). All dyed samples were profiled for banned aromatic amines through GC-MS. Only DR-28 released a listed banned amine, biphenyl-4,4''-diamine in significant quantities and was selected for UAR and MAR trials. Results of UAR for 10 min caused reduction equivalent to standard methods in case of leather and wool. Comparable results were also obtained in case of MAR reduction. Pertinent results were also confirmed using HPLC-DAD. The most economical methods were MAR with an energy saving ranging between 92 and 95% and a time saving of 70 to 80% (42-48 min) as compared to the standard methods. UAR methods provided energy and time savings of 80-85% and 22-42% (13-25 min) respectively. Greener approaches were found best for matrices in following order; leather > wool > cotton. Additionally a useful scheme was suggested for the non-destructive and greener analysis of ten lab-synthesized azo dyes using Fourier transform infrared spectroscopy with little or no sample preparation. The key region (azo band) appeared between 1504 and 1555 cm-1.
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شریمتی اندرا گاندھی

شریمتی اندراگاندھی
۳۰/جنوری۱۹۴۸ء کو گاندھی جی کے دردناک حادثۂ قتل کے بعد ۳۱/ اکتوبر ۱۹۸۴ء کووزیراعظم شریمتی اندراگاندھی کااپنے ہی حفاظتی دستہ کے دوظالم و سفاک نوجوانوں کی گولیوں کی بوچھار کا شکار ہوکرہلاک ہوجانا آزادی کے بعد سے اب تک وہ دوسرا نہایت الم ناک اوردردناک حادثہ ہے جس نے ملک وقوم میں دردوکرب اورشدت غم کی لہردوڑادی ہے، حقیقت یہ ہے کہ جب اندرا گورنمنٹ نے دربار صاحب امرتسر میں فوج بھیجنے کا اقدام کیاتھا ہمارا ماتھا اسی وقت ٹھنکا تھاکہ اب خیر نہیں ہے، کیونکہ جہاں تک خالصتان کے مطالبہ کاتعلق ہے وہ ایک خالص سیاسی معاملہ تھا اوراس لیے سکھوں میں ایک طبقہ ایسابھی تھا جو خالصتان کامخالف تھا لیکن دربار صاحب میں فوج کاداخلہ خالص ایک مذہبی معاملہ تھاجس پرسب سکھ متفق ہوگئے خواہ وہ خالصتان کے حامی ہوں یا نہ ہوں۔
ایک نفسیاتی اصول ہے کہ جب مذہبی جذبات بھڑکتے ہیں توانسان دیوانہ ہوجاتا ہے اوراس وقت وہ یہ نہیں سوچتا کہ جو کچھ ہوا ہے اس میں خود اس کی کم نظری یا غفلت کودخل ہے یا نہیں۔اس کے عتاب اورغضب کانشانہ صرف وہ شخص یا جماعت ہوتی ہے جس نے اس کے مذہبی جذبات کوبھڑکایا ہے، چنانچہ وہی ہوا جس کاہمیں اندیشہ پہلے سے تھا اورملک اندراگاندھی جیسی محبوب اورہر دلعزیز شخصیت سے محروم ہوگیا۔
اندراگاندھی کی ہر دلعزیزی اوران کی قائدانہ شخصیت کا ثبوت اس سے بڑھ کرکیا ہوسکتا ہے کہ ایک مرتبہ الیکشن میں اس طرح شکست کھاجانے کے بعد کہ ان کا اوران کی پارٹی کانام ونشان مٹ گیا اورملک میں جنتا گورنمنٹ قائم ہوگئی اس وقت بھی انھوں نے ہمت نہیں ہاری، حالانکہ ان کی مختلف طریقوں سے تذلیل کی گئی اوران کی توہین میں کوئی دقیقہ فروگذاشت نہیں کیاگیا۔ وہ اپنی تقریروں میں برابر یہ کہتی رہیں کہ جنتا گورنمنٹ بھانت بھانت کے...

ظاهرة الحذف في الجملة الفعلية دراسة نحوية دلالية في صحيح البخاري

Arabic language is one of the most developed languages of the world. It has a number of grammatical phenomenon, Omissions is one of them.                                                   Omission of any part of a sentence creates ambiguity to fully understand its meanings. Due to this phenomenon Arabic has a specific cause when viewed in the light of Semantic analysis. This study deals with the phenomenon of dropping or omission of the part of a speech. In article under review, I have explained as to how an omission becomes requirement of the text to reflect a particular meaning. I have chosen semantic study of three basic parts of verbal sentence that is Verb, Subject and Object to unveil this phenomenon in Sahih Al Bukhari. This clearly explains the significance of omission of words in the sayings of Holy Prophet Muhammad (Peace Be Upon Him).              

Integration of Indigenous Plant Extracts and a Fungus, Beauveria Bassiana Bals . for the Management of Tribolium Castaneum Herbst and Trogoderma Granarium Everts

The present study was conducted to check the toxic, growth inhibitory and combined effects of Azadirachta indica, Nicotiana tabacum, Eucalyptus globolus and an entomopathogenic fungus (EP), Beauveria bassiana against Tribolium castaneum and Trogoderma granarium. Plant extracts were applied on filter papers at a rate of 5, 10 and 15 % with the help of pipette, placed in petri-dishes, containg 50 g of wheat grains. One petri dish was kept as a control for each treatment containing untreated diet (wheat grains). Thirty 3rd instar larvae of Tribolium castaneum and Trogoderma granarium were released in each petri-dish and data regarding mortality was recorded after 24, 48 and 72 hrs. B. bassiana formulation (Racer TM) was applied at a rate of 0.3 x 108, 0.6 x 108 and 0.9 x 108 conidia/kg-1 of wheat grains. Three treated samples, each of 50 g were taken in separate small plastic jars and thirty 3rd instar larvae were used in mortality bioassay. The data regarding mortality was observed after 7, 14 and 21 days of treatment application. In the case of plant extracts, highest larval mortality 38.27 % was found against T. castaneum population of Bahawalpur (BWP) ethanol based A. indica extract, followed by 33.90 % in FSD with acetone extract at 15 % concentration after 72 hrs. The lowest mortality (11.33 %) was calculated in Bhakkar (BHAK) strain of T. castaneum with acetone extract of N. tabacum at 15 % concentration after 72 hrs. Highest mortality (35.02 %) was observed in BWP strain of T. granarium by ethanolic extract of A. indica while lowest (10.21 %) was recorded in acetone based extract. In the case of fungal toxicity bioassay, highest mortality (57.35 %) was found in the BWP population of T. castaneum, followed by Faisalabad (FSD) (50.61 %) after 21 days at concentrations of 0.9 x 108 conidia/kg-1 of wheat grains whilst lowest larval mortality (47.37 %) was observed in BHAK strain. In the case of T. granarium, highest larval mortality (54.41 %) was observed in BWP strain, followed by (46.25 %) of FSD strain. While lowest (44.43 %) was observed in FSD strain. Results of growth inhibition bioassays by extracts revealed highest pupal inhibition (66.65 %) was recorded in case of BWP strain of T. castaneum at 15 % of ethanol extract of A. indica followed by (62.06 %) as in FSD strain while comparatively low (48.27 %) was recorded in case of BHAK strain. Comparatively low pupal inhibition values were observed for T. granarium. Highest adult inhibition (48.18 %) was noticed in case of T. castaneum strain of BWP (with ethanolic extract of A. indica) while lowest (18.87 %) was observed in BHAK strain with ether extract of N. tabacum. In case of T. granarium, comparatively low adult inhibition inhibition values were observed. In case of fungus, highest pupal inhibition (56.76 %) was recorded for BWP strain of T. castaneum whilst comparatively low inhibition (43.97 %) for BHAK strains of T. granarium.In combined toxicity assays, mortality reached 77.32 % of at 15 % concentration of A. indica after longest exposure interval (21 hrs.) for T. castaneum (BWP strain) while comparatively low 71.05 % was noticed in case of T. granarium strain of Faisalabad. Pupal inhibition showed that67.81 and 58.62 % values were recorded in case of T. castaneum and T. granarium respectively, at highest treatment combination (15 % of A. indica + 0.9 x 108 of Racer TM) while the lowest inhibitions 30.62 and 19.70 %, respectively, were achieved at lower concentrations (5 % ofA. indica + 0.3 x 108 of Racer TM) of the treatment combination. Highest adult inhibitions (55.54 and 51.38 % of T. castaneum and T. granarium respectively) were recorded at highest treatment combination than 28.08 and 21.64 % noticed at lowest concentration combination of both treatments (extract + Racer TM). The overall results revealed that both bio-pesticides have proved very effective against both tested insect pests of stored commodities; especially their combined application can play a key role in IPM of stored grain insect pests. Bio-based insecticides can be used in integrated manner with other insect pest management tactics, save our expenses on traditionally used insecticides leading to potential and economical management the stored grain insect pests.