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Home > Development and Analysis of Batch and Continuous Crystallization Models

Development and Analysis of Batch and Continuous Crystallization Models

Thesis Info

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Author

Hussain, Iltaf

Program

PhD

Institute

COMSATS University Islamabad

City

Islamabad

Province

Islamabad.

Country

Pakistan

Thesis Completing Year

2012

Thesis Completion Status

Completed

Subject

Mathemaics

Language

English

Link

http://prr.hec.gov.pk/jspui/handle/123456789/205

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676725852405

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This thesis presents the development and simulation of batch and continuous crystallization models. Especially, models are derived for simulating batch and continuous enantioselec- tive preferential crystallization processes in single and coupled crystallizers. Such processes are highly important in chemical and pharmaceutical industries. The effects of nucleation, growth, and fines dissolution phenomena on the crystal size distribution (CSD) are inves- tigated. For the first time continuous preferential crystallization is investigated and the effects of different seeding and operating strategies on the process are analyzed. To judge the quality of the process some goal functions are used, such as purity, productivity, yield and mean crystal size of the preferred enantiomer. The semi-discrete high resolution finite volume schemes (HR-FVS) and the discontinuous Galerkin (DG) finite element method are proposed for solving these models. The resulting systems of ordinary differential equa- tions (ODEs) are solved by using explicit and nonlinearly stable high order Runge- Kutta method. The schemes satisfy the total variation bounded (TVB) property which guarantees the positivity of the schemes, for example the non-negativity of CSD in the present case. The suggested methods have capabilities to capture sharp discontinuities and narrow peaks of the CSD. In DG-schemes, the accuracy of the method can be improved by introducing additional nodes in the same solution element and, thus, avoids the expansion of mesh stencils which is normally observed in high order finite volume schemes. For that reason, the method can be easily applied up to boundary cells without loosing accuracy. It was found that the proposed numerical schemes have the capability to solve the given models more efficiently and accurately. The results support process design and optimization.
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۲۲؍رمضان المبارک ۱۴۱۸ھ مطابق ۲۲؍ جنوری ۱۹۹۸ء کوحضرت مولانا احمد رضا بجنوری کاانتقال ہوا۔جیسے ہی یہ خبر دفتر برہان میں پہنچی سب ہی رنج وغم میں ڈوب گئے۔کیونکہ حضرت مولانا احمد رضا بجنوری کاتعلق، واسطہ اور رابطہ ادارہ ندوۃ المصنفین اوررسالہ برہان سے روز اول ہی سے رہا۔ادارہ کے بانی مفکر ملت حضرت مفتی عتیق الرحمن عثمانیؒ سے حضرت مولانا کابھائیوں سے بھی بڑھ کرقلبی تعلق رہا۔ایک توہم سبق ہونے کی وجہ سے اوردوسرے استاد محترم حضرت مولانا انور شاہ کشمیری ؒ کے چونکہ مولانا احمد رضا داماد تھے اس لیے استاد کے داماد ظاہر ہے بھائی اور بہنوئی ٹھہرے۔
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Solid Phase Extraction of Heavy Metals Using Low Cost Sorbents

The aim of present work is to investigate the sorption capacity of salvadora persica, activated carbon, chitosan and chemically modified chitosan for heavy metals from dilute solutions. Salvadora persica was converted into powdered form and characterized by using Infrared spectroscopy. It has various organic compounds and these compounds contain sulphur, oxygen and nitrogen in their skeletons and behave superbly as coordinating ligands for cations present in the aqueous solution and hence causing effective sorption. Activated carbon was also prepared from salvadora persica under vacuum at 673 K with different soacking time. The prepared activated carbons were characterized using Surface Area Analyzer. Percentage yield of the prepared activated carbons in different heating times prior to washing was different. The activated carbon yields obtained at 673 K were 54.78 %, 52.27 % and 50.31 % at 30, 45 and 60 min heating time, respectively. The yield of activated carbons decreased as the heating duration increased. Surface area decreased from 375 to 27 m2/g. 4-Acryloylmopholine was reacted with chitosan to alter it chemically .The aim of treatement was to enhance binding sites for heavy metals ions. The amended chitosan holds different binding sites (chelating centers) in the form of oxygen and nitrogen. Different techniques were applied to illustrate the amended chitosan. Activated carbons, powdered salvadora persica, chitosan and the chemically modified chitosan were used as sorbents for different cations (Cu 2+, Cd 2+, Pb 2+ and Ni 2+ ). Among these cations copper showed highest sorption ability as compared to other and the sorption properties were in agreement with that of the Langmuir model. The activated carbon prepared at 30 min heating time, showed maximum sorption capacities for cations due to its larger surface area. The Freundlich, Langmuir and Temkin models (both linear and non linear methods) were used to assess the experimental statistics. For activated carbon and powdered salvadora persica, lower errors were shown by type one (I) of the Langmuir model as compared to Freundlich and Temkin models, so it is the appropriate model to explain the sorption phenomenon. Among the linear forms of the Langmuir isotherms, low error values were given by type four (IV) than other linear forms of Langmuir and the Freundlich model but higher than that of Temkin model, which shows that Temkin model fits better to the experimental data of chemically modified chitosan.