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Home > Efficacy Studies of Vitamin a Fortified Cookies in Pregnant and Lactating Women

Efficacy Studies of Vitamin a Fortified Cookies in Pregnant and Lactating Women

Thesis Info

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Author

Mahmood, Shahid

Program

PhD

Institute

University of Agriculture

City

Faisalabad

Province

Punjab

Country

Pakistan

Thesis Completing Year

2009

Thesis Completion Status

Completed

Subject

Applied Sciences

Language

English

Link

http://prr.hec.gov.pk/jspui/handle/123456789/586

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676726036843

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Present project was planned to alleviate the vitamin A deficiency in pregnant and lactating women by providing vitamin A fortified cookies. For the purpose, cookies were prepared by adding two vitamin A fortificants i.e. retinyl acetate and retinyl palmitate separately @ 30, 40 and 50% RDA of pregnant (750μg) and lactating (1200μg) women. During storage studies, moisture content and TBA no. of the cookies were increased from 2.51 to 2.84% and 0.40 to 0.69mg malenaldehyde/Kg, respectively. Vitamin A losses during baking and storage ranged from 7.95 to 15.79% and 8.02 to 9.69%, respectively, among the treatments. On the basis of physico-chemical analysis, baking & storage stability and sensoric attributes, T 4 (50% of RDA; retinyl acetate) and T 7 (50% of RDA; retinyl palmitate) were selected for efficacy purposes. Selected treatments (Five cookies; 50g per day) along with placebo were provided to the respective groups of vitamin A deficient pregnant women in third trimester. Retinyl acetate and retinyl palmitate fortified cookies significantly enhanced the level of serum retinol 18.51% and 21.56% in pregnant women and 9.43 and 12.84% in lactating mothers, respectively. In placebo group, the serum retinol level was significantly decreased up to 9.32% during pregnancy with a non-significant increase 1.81% during lactation. Collectively, the serum retinol level showed a significant increase of 29.69% and 37.16% in retinyl acetate and retinyl palmitate groups, respectively during six months whereas, a significant decrease (7.68%) was found in placebo group. Moreover, significant decrease was observed in retinyl esters level during pregnancy and lactation period; 35.90 and 32.00% in retinyl acetate and retinyl palmitate groups, respectively. Similarly, the placebo group also showed significant decrease in retinyl esters (64.84%). The level of β- carotene showed significant decrease in all treatments during pregnancy and lactation. Overall, T 1 (placebo) differed entirely from other groups with 36.45% decrease as compared to groups receiving retinyl acetate (8.18%) and retinyl palmitate (6.98%) fortified cookies. Red blood cells (RBC) indices like, hematocrit (Hct), mean corpuscular hemoglobin (MCH), mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC) significantly decreased in experimental groups during pregnancy, however, RBC indices depicted a significant increase in all groups during lactation. Collectively, a momentous increase in hemoglobin level was observed in women consuming retinyl acetate (12.31%) and retinyl palmitate (16.01%) in six months, while decrease of 6.15% was observed in placebo. The consumption of retinyl acetate and retinyl palmitate fortified cookies exhibited non-significant effects on renal & liver functions tests and lipid profile showing safety and suitability of these fortificants. Furthermore, retinyl palmitate was found to be more effective than retinyl acetate to uplift the serum retinol level in pregnant and lactating women. The upshots of the present investigation revealed that the cookies fortified with retinyl acetate and palmitate had potential to uplift serum vitamin A level in vulnerable segments with special reference to pregnant and lactating women.
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طاہر وحید

کوئی ملتا ہی نہیں سوختہ پا میری طرح
جس کو معلوم ہو وحشت کا پتا میری طرح
میرے جیون کو اُداسی سے ملانے والا!
دشت میں پھِرتا رہے آبلہ پا میری طرح
میں نے احباب کو آواز لگا کر پوچھا
کوئی رہتا ہے شبِ غم میں سدا، میری طرح؟
اے کئی دن سے مرے ذہن پہ چھائے ہوئے شخص
تو مجھے وصل کے سپنے نہ دکھا میری طرح
رات بھر چاند کو احوال سنانے کے لیے
کیا ٹھہرتی ہے دریچوں میں ہوا، میری طرح؟
زندگی! میری طرف دیکھ کے ایماں سے بتا
ایک بھی شخص کوئی تجھ کو مِلا، میری طرح
تند اور تیز ہواؤں کے علاقے میں سعید
زیست کرتا ہے فقط دل کا دِیا میری طرح

سیرت طیبہ صلی اللہ علیہ وآلہ وسلم کا عدلیاتی پہلو: ایک تحقیقی جائزہ A Research Review of the Prophetic Justiceﷺ

Islam is a religion of peace and it has provided a strong system of justice for the establishment of peace and order, the practical picture of which is available to the Muslim Ummah in the form of Sira-e-Taiba of the Holy Prophetﷺ. On which the seal of beauty has been recorded by Allah Himself. Therefore, the system of justice of Islam can be used only when the solution of all issues is sought from Sira-e-Taiba because Heﷺ has eliminated the distinction between rich and poor in the supremacy of law. The Holy Prophet ﷺ has set great and enlightening examples of justice for humanity, the pursuit of which leads to peace and tranquility of social life. In his Supreme Court, the Qur'an and Sunnah and consensus and analogy were of fundamental importance. In the Qur'an and Hadith, Sira-e-Taiba had the status of Shāri' and Legislator, while in consensus and speculation, Sira-e-Taiba has promoted thinking and counseling. The center and axis of Islamic law is your caste. He ﷺ has established justice, supremacy, and law in every field of worship, affairs, disputes, and crime. Therefore, in this article, the judicial aspect of His ﷺ Sira-e-Taiba has been explained in the light of the Qur'an and Hadith, the Sahabah and the followers, and the edicts of the Imams and jurists.

Impact of Local Climate Change on Plant Biodiversity of Murree Hills

The present research work was carried out to determine the impact of local climate change on plant diversity of study area, Murree Hills, through phytosociological, carbon sequestration and biomonitoring potential. For this purpose the study area was divided into eleven sub sites comprising the Reserve Forests, in which the phytosociological attributes and carbon sequestration potential was investigated. Moreover, the impact of automobile exhaust was also assessed on three selected tree species that were planted along five busiest roads of Tehsil Murree, the biochemical attributes i.e., % moisture content, total chlorophyll contents and carotenoids in the leaves of these trees were determined and their mean values were compared, with the mean values obtained from the controlled trees, growing far away from the busiest roads. During phytosociological assessment, 229 plant species in 295 quadrats belonging to 66 plant families were recorded. Among these, Pteridophytes represented three plant families having 6 plant species, Gymnosperms one plant family having 4 plant species, Angiopserms by three Monocot families having 34 species and fifty nine Dicot families having 185 species. TWINSPAN analysis separated these plants into two major groups on the basis of % Cover which were further divided into subgroups and associations according to their plant community structure. Carbon sequestration potential was assessed at three levels i.e. above ground, understorey and soil and above ground potential of forest with respect to dominant tree species i.e. Pinus wallichiana was found 4281.43 (t/ha), under storey vegetation having 3.046 (t/ha). The carbon sequestration potential of study area taken at two depths (1-15 cm & 16-30 cm) was 54.61 and 42.93 (t/ha), respectively, indicating the forest as a major carbon sink of GHGs. It was noticed that overcrowding and unmanageable tourist number was resulting in increasing the smoke and temperature in the study area when assessed through biochemical attributes of the selected trees i.e., Aesculus indica, Populus ciliata and Pinus wallichiana. The amount of dust (g) deposited on leaf samples was comparatively higher on road side tree samples, i.e. IX 0.33-0.12 as compared to the control, i.e. 0.19-0.06 in tree samples. Moreover, all the parameters i.e., % moisture content, total chlorophyll content and carotenoids showed remarkable decrease in their quantities in road side tree samples as compared to the control ones. The value of % moisture content was ranging 64.06-21.97 in control samples and 61.43-8.84 in tree samples, while total chlorophyll contents from 6.32-3.66 in control samples and 6.28-3.86 in tree samples where as carotenoids 6.98- 5.34 in control and 6.44-5.34 in tree samples. It is important to mention that there was an increase of annual rain fall (118.21-140.51mm), maximum day temperature (16.83- 18.11°C) and minimum (8.16-9.27°C). The above mentioned values thus obtained, clearly indicate enhanced anthropological activities in the study area, and resulting in the local climatic changes which could be a step forward in global warming. Such studies can be helpful to determine the dynamics of the forest and distribution of plant diversity. Therefore, future strategies can be devised to implement sustainable approaches to conserve the plant diversity at Murree.