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Existence Theory and Numerical Solutions of Boundary Value Problems for Fractional Differential Equations

Thesis Info

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Author

Amjad Ali

Program

PhD

Institute

University of Malakand

City

Malakand

Province

KPK

Country

Pakistan

Thesis Completing Year

2017

Thesis Completion Status

Completed

Subject

Mathemaics

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/12946/1/Amjad%20Ali_Math_UoMalakand_2017_HSR_21%20Dec.%202017.pdf

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676726153243

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In this dissertation, we investigate different types of boundary value problems of nonlinear fractional order differential equations. The concerned research is associated to the existence and uniqueness of solutions, Hyers–Ulam type stability and numerical analysis for fractional order differential equations. We develop sufficient conditions for existence and uniqueness of solutions for fractional differential equations, with the help of classical fixed point theory of Laray Schauder type, Banach contraction type and Topological degree method. Further, we investigate the conditions for stability analysis of fractional differential equations. One of the important area of fraction differential equation is known as hybrid fractional differential equation. Hybrid fractional differential equations has an efficient techniques used for modeling various dynamical phenomenon. Therefore, for investigation sufficient conditions for existence and uniqueness of solutions hybrid fractional differential equations, we have used Hybrid fixed point theory established by Dhage and develop sufficient conditions for the existence and uniqueness of solutions of hybrid fractional differential equations. On the other hand, in most cases the nonlinear fractional differential equations are very complicated to obtained an exact analytic solution. Although, if an exact solution is possible, that needed very complicated calculations. Therefore, we paid a strong attention to the numerical solution of fractional differential equations and fractional partial differential equations. We have developed some powerful and an efficient numerical techniques for the approximate solutions of both linear and nonlinear fractional order differential equations. The established technique are based on Laplace transform coupled with Adomain polynomials to obtain the aforesaid solutions in the form of convergent series. Further, we also develop another interesting and useful method based on operational matrices obtained via using Lagendre polynomials. With the help of these mentioned techniques, we solve both linear and nonlinear ordinary as well as partial fractional order differential equations. We consider some fractional order differential equations for illustrative purposes and numerical approximations of their solutions are obtained using MAPLE and MATLAB. The numerical results obtained via aforesaid techniques, are compared with other standard techniques. Which shows, that how the Laplace transform coupled with Adomain polynomials and operational matrices obtained by Legendre polynomials are more effective and reliable, than the standard ordinary differential equations solvers.
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میر واعظ مولوی عمر فاروق

میرواعظ مولوی محمد فاروق صاحب کی شہادت
میرواعظ مولوی محمدفاروق کچھ سر پھروں کی گولیوں سے چھلنی ہوکر شہید ہوگئے۔ اِنَّالِلّٰہِ وَاِنَّا اِلَیْہِ رَاجِعُوْن ط
یہ خبر جیسے ہی عوام تک پہنچی، سب ہی پرسکتہ ساچھا گیا، ہرشخص غم وصدمہ کے سمندر میں ڈوب گیا، کیونکہ میرواعظ ؒ ایک قابل احترام ہستی کانام تھا، وہ کشمیری عوام کے ہی محترم رہنما نہ تھے ،بلکہ ملّتِ اسلامیہ ہند کے سچے رہنما تھے۔ عالم وعابد اورزاہد تھے۔بڑے ہی وضعدار انسان تھے۔ہرشخص سے مروت واخلاق کے ساتھ ملتے تھے۔ ۱۹۸۶ء میں راقم اپنے رفیق فخرالدین صاحب کے ہمراہ سری نگر گیاتو حضرت میرواعظؒ ہی کے یہاں قیام کیا۔ اس دوران میں ان کی میزبانی کے جوہر وآداب کامشاہدہ تو ہواہی، ساتھ ان کی تقویٰ وعبادت سے لبریز زندگی، ان کے اعلیٰ اخلاق وبہترین ومثالی کردار کے جونمونے نظروں کے سامنے آئے اس کے پیش نظر راقم یہ کہے بغیر نہ رہے گاکہ کشمیر میں ان کی شخصیت اسلامی کردار وعمل تقویٰ وریاضت اور ملک وقوم کی ہمدردی ومحبت میں منفرد تھی۔
ہزاروں سال نرگس اپنی بے نوری پہ رُوتی ہے
بڑی مشکل سے ہوتا ہے جہاں میں دیدہ ور پیدا
قبلہ ابّاجان حضرت مفتی عتیق الرحمن عثمانیؒ اوران کے قائم کیے ہوئے ادارہ ندوۃ المصنفین سے جوان کو لگاؤ وعقیدت تھی وہ اظہر من الشمس ہے ،وہ اس ادارہ سے دلی وابستگی کابرملا اظہار کیاکرتے، اس کی امداد واعانت کے لیے ہمیشہ پیش پیش رہتے۔ ان کی شہادت سے ادارہ ندوہ المصنفین کاذاتی نقصان ہواہے،لیکن اﷲ پاک نے ان کو ان کے بہترین عمل وکردار کی بدولت جوشہادت کا مرتبہ دیا ہے اس سے انہیں مقرب الٰہی رحمت خاص اورجنت کاجومژدہ ملاہے اس پر ہر مسلمان کورشک ہے۔
اﷲ تعالیٰ ان کے متعلقین اورہم سب کو صبرجمیل عطا فرمائے،آمین۔ ان کے صاحبزادے اور ان کی جگہ میرواعظ مولوی عمر فاروق...

فکر اقبال کے تناظر میں تہذیبی تصادم

A thorough critical analysis of human history highlights that the clash of civilizations centered on themes of conflict, war, and struggle. Historical experts use the word encounter to interpret or explain these relations among civilizations. Trade played a vital role in flourishing these ties, however, conflict and encounter have also been a part of almost all the phases or eras of human history. Developing nations have always looked up to the western world as a role model of economic and military progression, but this philosophy has also resulted in the escalation of tensions among these nations. World peace faces daunting challenges and is one of the most talked-about human concerns in the present times. Islam is currently being challenged by the western world in terms of the right interpretation of religious teachings and the true message of the Holy Quran and Sunnah. Islam is still struggling to make its mark in the present world order, particularly after the 9/11 incident which painted Muslims as terrorists and fundamentalists. It is quite evident that the world is divided into factions or groups, where one group is the torchbearer of Islam and religious teachings, while the second group endorses western ideals or secularism. According to Samuel Huntington, it won’t be wrong to say that the next ideological challenge that the world faces after the ultimate demise of the Soviet Union is Islam and the prospective clash between the East and the West in the 21st century will be the most discussed topic. The present-day relationship between the East and the West is based upon rivalry. This conflict is not a new area of research and is centuries old. The only solution to this problem is to promote global peace and harmony and facilitate dialogue among nations. This would help in creating a social system that can center on values, harmony, peace, and love. Also, Iqbal’s philosophy can act as a guiding stone and can help in resolving this crisis. Iqbal’s universal social reconstruction theory highlights how different civilizations can live together and can facilitate constructive dialogue to improve civilizational ties. This article aims to incorporate the teachings of Iqbal, especially the universal social reconstruction theory to propose solutions for inter-civilizational clashes. This article aims to use the teachings of Iqbal as a beacon of light to promote constructive dialogue and peaceful coexistence among the two dominant sides of the world, resultantly leading in much prosperous and peaceful world order. 

Association of Tissue Vitamin D Receptor Expression With Breast Cancer Molecular Subtypes in Kenyan Women

Background: Previous studies have shown that reduced vitamin D receptor expression in breast cancer tissue is associated with worse disease outcomes. Furthermore, studies show that estrogen negative and triple negative breast cancer is associated with a poor prognosis and a low breast tissue vitamin D receptor (VDR) expression. Other studies also report that low serum vitamin D levels are associated with more aggressive breast cancer. Methods: This was a cross-sectional study with both a retrospective and a prospective arm. The retrospective part was nested within a larger study; previously constructed tissue microarray blocks (TMA) blocks were used for analysis of VDR expression. The prospective arm recruited women who underwent a breast biopsy for suspicious breast lesions in whom blood samples for serum vitamin D levels and tumour VDR immunohistochemistry were collected. Questionnaire data on pre-determined patient and tumour characteristics were extracted from the charts. Tissue expression of VDR was analysed on immunohistochemistry and serum vitamin D levels assayed. Results: A total of 214 cases were recruited retrospectively and 24 prospectively. There was a statistically significant difference in the VDR score of the Triple negative breast cancer (TNBC) subtype compared to the other subtypes (p value = 0.047, test = ANOVA: Kruskal Wallis Test). There was a positive correlation of VDR score and tumour size. There was a weak negative correlation between VDR score and human epidermal growth factor receptor 2 (HER 2) but no correlation with ER and PR. There was a positive correlation between serum vitamin D levels and VDR Immunoreactive score (IRS). Conclusions: Our results suggest that low or negative VDR score is a marker of poor prognosis in breast cancer as the expression was low in TNBC. However, high VDR score was not associated with ER or PR expressing tumours. The weak negative correlation with tumour size suggests an association of low VDR expression with aggressive tumour features. A randomized controlled trial exploring the utility of vitamin D supplementation or other VDR ligand analogues in TNBC is recommended. A larger study is recommended to determine if indeed there is a correlation between serum vitamin D levels and VDR expression.