منشی احترام علی کاکوروی
افسوس ہے کہ منشی احترام علی صاحب کاکوروی نے ایک طویل علالت کے بعد انتقال کیا، وہ ایک نامور باپ منشی احتشام علی صاحب مرحوم رئیس کاکوروی کے فرزند اور خود بھی بڑی خوبیوں کے انسان تھے، دارالعلوم ندوۃ العلماء سے ان کو موروثی تعلق تھا، وہ اس کے معتمد مال تھے، ایک زمانہ میں لکھنؤ کے مقامی قومی کاموں میں بھی حصہ لیتے تھے، لیکن ادھر کچھ دونوں سے خانہ نشینی کی زندگی اختیار کرلی تھی لکھنؤ کا مسلم یونیورسٹی کنونشن ان ہی کی کوشش کا نتیجہ تھا، وہ پشتینی رئیس تھے، لیکن طبعاً نہایت متواضع، خلیق اور شرفائے اودھ کی تہذیب و شرافت کا نمونہ تھے۔ اﷲ تعالیٰ ان کی مغفرت فرمائے۔
(شاہ معین الدین ندوی، فروری ۱۹۶۶ء)
The Quran describes itself as a book of guidance. Sura l-Baqarah, verse (67) states: قَالَ أعُوْذُ بِاللّٰہِ اأنْ أَکُوْنَ مِنَ الْجَھِلِیْنَ۔He said, "I seek refuge in Allah from being among the ignorant. "The Qur'an does not render a coordinated description of the universe Creation and how it will end. In lieu of a continuous story of creation and cease, there are verses dispersed all over the Quran which deal with certain aspects of the universe’s Creation and end. These scattered verses provide information on the sequential events marking its development with varying degrees of detail. The primary objective of this paper is to analyze the Quranic Concept of Universe. The idea of steady state by Hermann Bondi, Thomas Gold, and Fred Hoyle (1948) suggests that this universe is created with big bang, it is expanding and it would be the same, always static, always contracting or always expanding with no end. This is in contrast with the pulsating theory of the accelerating expansion will result in weak gravity which will cause the universe to contract. When this contraction will condense everything back into one single point, this rapid compression will lead to another explosion (often referred to as mini big bang). As a result of which the universe will start expanding again. Hence it results in a pulsating universe in which there is alternate expansion and contraction of universe.
Nanotechnology is known as the science of recent era and its applications have been extended in various fields like chemistry, biology and physics. This field of science deals with nanoparticles (NPs) having dimension between 1-100 nm. Different types of NPs are currently being synthesised. Among them, silver nanoparticles (AgNPs) have known to possess the antimicrobial potential due to their large surface area and small size. Pakistan is an agricultural country accounted for 18.9% of the GDP. Citrus is an important horticultural and economically important small sized tree fruit crop around the world. Average yield of Citrus reticulata (Mandarin) in Pakistan is low as compared to the developed country. The low yield of Mandarin is due to attack of different microbial diseases. Among different microbial diseases, canker is major disease of Mandarin and 30% is lost due to canker disease. The major objective of this study is to find the potential role of AgNPs for improving the tolerance against canker disease. AgNPs were synthesised using leaves extract of Moringa oleifera as the main reducing and stabilising agent. The synthesised AgNPs were characterised through UV-Visible spectroscopy, Zeta Analyser, SEM, XRD and EDX. Different concentrations (10, 20, 30, and 40 ppm) of the synthesised AgNPs were exogenously applied on Mandarin to record disease incidence against canker disease. It was found that no concentration of synthesised AgNPs completely inhibited canker disease. The effect of AgNPs on the intensity of canker disease varied greatly and 30 ppm was found to be the most suitable concentration for enhancing the tolerance against canker disease. Different enzymatic (CAT, SOD, and POD) and non-enzymatic (TPC, TFC, Proline content, MDA, protein content) activities were also explored in response to various concentrations of AgNPs under canker stress. It was found that plants which were treated with pathogen only showed the enhanced enzymatic and non-enzymatic activities. Fruit quality (Juice content, pH, Vit C) and fruit productivity (yield per plant, fruit weight, ED, PD and PT) parameters were significantly enhanced when plants were exogenously sprayed with 30 ppm AgNPs. Proteome analysis was also done in the leaves and seeds samples of mandarin and functional categorization were done through MapMan Bin Codes Software. It was found that plant defense related proteins were more up-regulated and stress related proteins were down-regulated in response to 30 ppm AgNPs under biotic stress. So, it can be concluded that plant based synthesised AgNPs have the potential to enhance the tolerance against canker disease. Further studies are required to explore the molecular mechanism and interaction of NPs inside the cell.