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Home > Isolation and Characterization of Alkaloids: Study of Ddelphinium Chitralense and Related Medicinal Plants.

Isolation and Characterization of Alkaloids: Study of Ddelphinium Chitralense and Related Medicinal Plants.

Thesis Info

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Author

Shujaat Ahmad

Program

PhD

Institute

University of Malakand

City

Malakand

Province

KPK

Country

Pakistan

Thesis Completing Year

2017

Thesis Completion Status

Completed

Subject

Chemistry

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/12945/1/Shujaat_Ahmad_Chemistry_HSR_2017_UoM_Malakand_15.06.2017.pdf

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676726528813

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The present Ph.D thesis describes the phytochemical and biological exploration of two species belong to family Ranunculaceae of District Dir (U), Khyber Pakhtunkhwa Pakistan. The main goal of our research was the isolation, structure elucidation, selective AChE and BChE enzyme inhibition of C19 and C20 diterpene alkaloids from the basic chloroform soluble fraction of D. chitralense and D. denudatum Wall. Seven new compounds; Chitralinine-A (1), Chitralinine-B (2), Chitralinine-C (3), Chitraline-A (4), Chitraline-B (5), Chitraline-C (6), Chitraline-D (7) and two known, Ajaconine (10) and Delectinine (11) have been isolated from the aerial part of D. chitralense. Two new Jadwarine-A (8) and Jadwarine-B (9) and one known dihydropentagynine (12) have been isolated for the first time from the aerial parts of D. denudatum Wall. All the isolated compounds (1-12) were characterized by various spectroscopic techniques and screened for enzyme inhibition activities (AChE & BChE). The isolated compounds were found to be potent AChE and BChE inhibitors. Our present findings indicate the interest of C19 and C20 diterpenoids as potent AChE and BChE inhibitors present in the investigated two delphinium species. They may contribute towards naturally accessible inhibitors used for the treatment of Alzheimer’s disease.
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الفصل الثانی: أسلوب نازك الملائكة وأهم دواوينها

الفصل الثانی: أسلوب نازك الملائكة وأهم دواوينها
المبحث الأول: ممیزات أشعار نازك الملائکۃ
یوجد في شعر نازک الملائکۃ ’’القیمۃ الفعلیۃ‘‘ وھذہ القیمۃ لا تتمثل في أن شعرھا قابل للتقلید أو أخذہ کنموذج مثالي یقتدي بہ من بعدھا الآخرون، ولکن المیزۃ الممتازہ في شعرھا بأن لدیھا القدرۃ علی التحرر من العاطفۃ والرومانسیۃ وما إلی ذلک۔
ویذکر شوقي بزیغ في مجلۃ العدد’’ وقد تکون تربیۃ نازک المحافظۃ ونشأتھا في أسرہ متعلقۃ بأھداب القیم الموروثۃ ھي من بین العوامل التي دفعتھا إلی احترام العادات والتقالید المحیطۃ لھا من کل جانب، وعلی الرغم من إقامتھا الطویلۃ في أمریکا فنحن لا نلمع في شعرھا ما یشي بالتجرؤ علی الأعراف السائدۃ وتجاوز المحظورات لابل إننا نکاد لا نعرف شيئاً عن حیاتھا الخاصۃ أو عن علاقاتھا العاطفیۃ التي سبقت الزواج‘‘ ۔
فیذکر شوقي بزیغ لا بد من الاعتراف بأن نازک، بسبب النشأۃ أو الخوف أو مکانۃ المرأۃ العربیۃ أو بعض الظروف الاجتماعیۃ لم تسمح للشاعرۃ أن تتعمق في الحداثۃ أو بما تکون الحالۃ الاجتماعیۃ أو مکانتھا أو عادات البيئة العربیۃ والواقع العربي والعراقي بوجہ خاص وقد تکون ھذہ الظروف نفسھا ھي التي لونت معظم قصائدھا بلون الحزن والألم ، وجعلت الموت یحتل موقعاً متعلقاً في نظرتھا، ولکن الجانب الإیجابي یحجب علی حزنھا ویظھر الجانب الآخر وھي قدرتھا علی تحویل حزنھا إلی مادۃ للتأمل الھادئ والتبصر العمیق والتعجب في الحیاۃ وفي أحوال النفس وأسرارھا، وھو ما تکمن ملاحظتہ في قصائدھا مثل "أجراس سوداء" و "مرثیۃ یوم تامہ" و "الشخص الثاني" و "الخیط المشدود في شجرۃ السرو" وغیرھا ۔ نلاحظ أن معظم قصائدھا ملون بلون الحزن والألم وقد تکون أسبابھا لیست ظاھرۃ ولکن ربما یکون ھناک سر مختبيئ في قلب الشاعرہ، وھي لا تستطیع إظھارہ وذلک بسبب حالة من الحالات أو بسبب ظروف معینۃ ویتضح ألمھا الداخلي ونظرتھا الی الوجود والأشیاء، بأنھا فانیة لا حیاۃ لھا۔

افراد سازی میں خصوصی دلچسپیوں اور رجحانات کی رعایت سیرت طیبہ کی روشنی میں

One of the aspects of the teaching and grooming of people by the the of tendencies and interest special the considering was (صلى الله عليه وسلم) Prophet companions and preparing, guiding, grooming and appreciating them in their respective fields of special interests and tendencies. This consideration of their special interests and tendencies and grooming and guiding them in this respect enabled them to exercise their abilities and serve the society in the academic, preaching, political, economic, social, judicial, diplomatic and other aspects. Until and unless the interest and tendencies of youth are not kept in mind, abilities of youth can never be utilized. Our Holy Prophet (ﷺ) took great care of youth’s interests before their training for specific field. The present paper intends to analyze the life of five companions and their excellence in field of education which was result of the Prophet’s consistent guidance and grooming according to their special interests and tendencies which resulted in their extra ordinary status in their respective fields and constructive contribution in the establishment and strengthening the structural foundations of society. The present Muslim world is in the need of seeking the guidance from the life of the Prophet in this respect and considering the special tendencies and interests of the youth and grooming, guiding and upbringing them in their respective fields so that they could contribute to the positive and constructive upbringing of the humanity in general and Muslim society in specific.

On board intelligent black box

This product is named as Onboard Intelligent DeviceOBID. It will be fittedin nominated public transport buses. This device will essentially collect and store data from the vehicle network. The device functionality is divided into three categories which are Environment Sensing, Vehicle Management and Security. The objective is to increase the vehicle's capability to automate and perform various functions such as monitoring the internal parameters, the engine’s condition, location of the bus and passenger notifications. The processor will communicate all the dynamics with a control center which will be accessible to the public. It will also be able to take smart decisions when encountered with familiar situations. The collected data is analyzed in the form of graphs and charts generated by the software which is deployed at the control center. With the help of acquired data carbon footprints, fuel consumption, traffic emissions, vehicle health, predicting the driver behavior, forecasting of rush-hours and predicting the vehiclemaintenance requirements can be estimated. The device is packaged in to a box with proper considerations of reliability in terms of power, interface terminals, storage and cabling. The OBID is a step towards automation and control and will help monitor and control parameters better than before. This data will help the concerned people in the whole process of taking any required action on time. The biggest advantage is that people can plan their journeys ahead of time