Growth in Islamic Economy

A major proof viewed by the Islamic universe today is the proof of re-making and reorganizing the economy in such a way seen as similar to the motivation of Sharia’h work. Money-related new development is one of the topics that in a general sense is termed as a science that offers a technique to show the science of monetary angles. Nevertheless, the standard technique, which has been assembled, is being considered for dissatisfaction in dealing with the issues of the Ummah, for example, despair, backwardness in human resources (HR), and achievement in proper position and life, and even a matter of natural change. Sadly, those conditions are found overwhelmingly in the Muslim world, where they have essentially manifested and represented in Muslim life. Moreover, it seems that the uniqueness of the Muslim world has been challenging, that is, it is typically rich in asset but still weak and poor. As for the path, in Muslim society, there is an ignorance of the achievements of motivation. Thus, there is no possible norm to find the emergence of different methodologies within the Islamic structure, surprisingly in the area of ​​money-related to unforeseen development.

Raman Spectroscopy Based Diagnosis of Dengue Virus Infection in Human Blood Serum.

Dengue virus (DENV) infection is a mosquito born infectious disease. Its diagnostic is utmost important for treatment, as the symptoms of disease are quite similar to other diseases. Current pathological diagnostics methods available are reverse transcriptase polymerase chain reaction (RT-PCR) and enzyme linked immunosorbent assay (ELISA). RT-PCR is used to detect the virus itself while ELISA is used to detect non-structural protein-1 (NS1) and antibodies like immunoglobulin-M (IgM) and immunoglobulin-G (IgG). Existing methods e.g. virus isolation, RT-PCR and ELISA have certain disadvantages like more time consuming, false-positive/false-negative results and expensive as compared to Raman spectroscopy. Raman spectroscopic technique provides molecular signatures, minimum running cost and online results. Raman spectra of biological samples combined with a suitable statistical data-mining technique like partial least squares (PLS) regression can be used to devise a new method for diagnosis of DENV infection in human blood sera. In present studies, this technique is successfully applied for the diagnostic of DENV infection based on three steps. A graphical user interface (GUI) was specially designed and its code was developed in MATLAB (Mathworks 2009a) programming language to implement PLS for the presented research work. First step: Raman spectra of ELISA confirmed NS1 positive and negative sera samples are discriminated by PLS regression. Analysis of regression coefficients, which differentiate these groups, shows an increasing trend for phosphatidylinositol, ceramide and amide-III, and a decreasing trend for thiocyanate in the DENV infected serum. Second step: Raman spectra of samples, with known value of ELISA based AI of IgM are discriminated by PLS regression. Analysis of regression coefficients revealed that concentration of asparagine, glutamate, galactosamine etc. were found to increase while concentration of fructose, cholesterol, cellobiose, and arabinose were found to decrease with increasing values of antibody index (AI) of IgM. Third step: Raman spectra of samples, with known value of ELISA based AI of IgG are discriminated by PLS regression. Analysis of regression coefficients revealed that myristic acid, coenzyme-A, alanine etc. were found to increase, while amide III, collagen, proteins, fatty acids, phospholipids and fucose were found to decrease with increasing values of AI of IgG. Raman spectroscopy provides not only the diagnosis of DENV infection, but it also enables the detailed insight of the abnormalities appearing in molecular composition of a sample. Importantly, Raman spectra @ 532 nm excitation were used to investigate the possible use of lactate as biomarker for DENV infection. It was found that spectral difference in healthy and infected samples is due to an elevated level of lactate in DENV infected group.