The study is carried out on the gross anatomy, biometry and radiographic analysis of tarsal bones in twenty specimens of male and female adult Chinkara (Gazella bennettii) at the University of Veterinary and Animal Sciences (UVAS), Lahore, Pakistan. The tarsus of Chinkara comprises of five bones both grossly and radiographically, settled in three transverse rows viz, tibial and fibular tarsal in the proximal, central and fourth fused tarsal in the middle row, while, the first, second and third fused tarsal in the distal row. The fibular tarsal is the largest and longest bone of the hock, situated on the lateral side and had a bulbous tuber calcis "point of the hock" at the proximal extremity which projects upward and backward. The tibial tarsal bone is the 2nd largest bone of the proximal row, lies on the medial side of the tarsus and bears trochlea at either end. The central and the fourth tarsals are joined to form a large bone which is extended across the entire width of the tarsus and articulates with all bones of the tarsus. The first tarsal is a rectangular piece of bone sited on the posteromedial surface of the hock. The second and third fused tarsal bone resembles the central but is smaller and wedge-shaped. It is situated between the central tarsal bone proximally and the large metatarsal bone distally. The average maximum height and breadth for fibular tarsal, tibial tarsal, central and fourth fused tarsal, first tarsal, second and third fused tarsal are (5.61±0.23 cm and 2.06±0.13 cm), (2.79±0.05 cm and 1.74±0.01 cm), (1.51± 0.13 cm and 2.08±0.07cm), (0.61 ±0.01 cm and 1.10±0.06 cm) and (0.98±0.01 cm and 1.49±0.01 cm), respectively. GROSS AND CLINICAL ANATOMY OF THE SKULL OF ADULT CHINKARA (GAZELLA BENNETTII) The objective of this study was (1) to study gross morphological, osteometric and clinical important landmarks in the skull of adult Chinkara to obtain baseline data and (2) to study sexual dimorphism in male and female adult Chinkara through osteometry. For this purpose, after performing postmortem examination, the carcass of adult Chinkara of known sex and age was buried, after a specific period of time the bones were unearthed. The shape of the Chinkara skull was elongated and had thirty two bones. The skull was comprised of the cranial and the facial part. The facial region of the skull was formed by maxilla, incisive, palatine, vomar, pterygoid, frontal, parietal, nasal, incisive, turbinates, mandible and hyoid apparatus. The bony region of the cranium of Chinkara was comprised of occipital, ethmoid, sphenoid, interparietal, parietal, temporal and frontal bone. The foramina identified in the facial region of the skull of Chinkara were, infraorbital, supraorbital foramen, lacrimal, sphenopalatine, maxillary and caudal palatine foramina. The foramina of the cranium of the Chinkara skull were the internal acoustic meatus, external acoustic meatus, hypoglossal canal, transverse canal, sphenorbital fissure, carotid canal, foramen magnum, stylomastoid foramen, foramen rotundum, foramen ovale and jugular foramen, and the rostral and the caudal foramina that formed the pterygoid canal. The measured craniometric parameters did not show statistically significant differences (p>0.05) between male and female adult Chinkara except palatine bone, OI, DO, IOCDE, OCT, ICW, IPCW, and PCPL were significantly higher (p>0.05) in male than female Chinkara and mean values of the mandibular parameters except b and h were significantly (p< 0.5) higher in male than female Chinkara. Sexual dimorphism exists in some of the orbital and foramen magnum parameters, while high levels of sexual dimorphism identified in mandible. In conclusion, morphocraniometric studies of Chinkara skull made it possible to identify species specific skull and use clinical measurements during practical application.
وہی ہوا کہ تماشا لگانا پڑ گیا ناں بڑا تھا شوق تمھیں سیدھی رہ دکھانے کا سمجھ میں آیا کہ ہم لوگ چیختے کیوں تھے جو لوگ دوستی کو بزدلی سمجھتے تھے ستارا وار ابھرنے لگا ہوں آنکھوں سے یہ لوگ موت سے کم پر تو خوش نہیں ہوتے
تمھیں بھی دکھ کو صحافت بنانا پڑ گیا ناں تمام شہر مخالف بنانا پڑ گیا ناں تمھیں بھی خوف رجسٹر کرانا پڑ گیا ناں اب امن کے لیے جرگہ بٹھانا پڑ گیا ناں دیے کی لو کو بڑھانا گھٹانا پڑ گیا ناں سو زندہ رہنے کو مر کر دکھانا پڑ گیا ناں
تهدف الدراسة لتحليل حديث ابن عمر -رضي الله عنهما- في المبيت في مِنَى، والذي يعدُّ أصلا في مسألة المبيت ودارت عليه فتاوى الائمة الفقهاء. اتبع الباحث منهجاً واضحاً في إعداد تمثل في عزو الايات القرآنية لسورها، وتخريج الأحاديث من كتب السنة المعتبرة، والاستعانة بأقوال العلماء وشراح الحديث في فقه الحديث وشرحه، وعزو الأقوال لمصادرها الأصلية ما وسعني ذلك، أو بواسطة عند الحاجة. وتوصلت الدراسة إلى مجموعة من النتائج أهمها وجوب المبيت بمنى على الحاج، ومَن ترك المبيت ليلة فلا شيء عليه، ومن ترك المبيت بالكلية فيلزمه دم لتركه منسكا من المناسك، ومَن لم يجد مكانا بمنى فيبيت بأقرب مكان لها مراعاة لاتصال الحجيج.
الكلمات المفتاحية: حديث ابن عمر، المبيت في مِنى، اركان الإسلام، السيرة النبوية، السنة النبوية.
Present research work was planned to study teratological effects of sodium arsenate in developing Mus musculus (mammalian model). Due to deficiencies in literature regarding orally induced teratogenicity of arsenate in developing mammalian embryos, this study was designed. Additionally, garlic (Allium sativum) extract was used to check its protective potential against sodium arsenate induced teratogenicity. LD50 value calculated in pregnant females was 147.00 µg/g B.W. Exposure groups were divided into acute (single exposure group GD6, double exposure group GD6 & 12, multiple exposure group GD6, 9 &12) and sub-acute (continuous GD 6 to12, dose + antidote group GD6 to12). Each acute and sub-acute exposure groups were further divided into three concentrations of sodium arsenate i.e. 18.25 µg/g B.W., 35.50 µg/g B.W. and 75.00 µg/g B.W, based upon the 12.5%, 25% and 50% of calculated LD50 values. Along with acute and sub-acute groups control and vehicle control groups were also maintained. On GD18, the pregnant females were anesthetized and gravid uteri were dissected out. The fetuses were recovered, weighed, observed and were preserved for further studies. A trend of decrease in maternal body weight with increase in concentration and exposure of sodium arsenate was seen together with increased number of still fetuses as compared to control and vehicle control groups. Fetal body weight, CR length, head and eye circumference, limb size and tail length showed a gradual decrease when compared with respective control and vehicle control groups. A dose dependent increase in morphological abnormalities like microcephaly, exencephaly, microphthalmia, anophthalmia, omphalocoel, kyphosis, scoliosis, open eye, runt fetuses and kinky tail were mainly observed during the studies.Histologically, ii defects such as spina bifida, meningomyelocoel, hydrocephaly and enlarged ventricles were noticed. Besides this ventricular septal defects, lungs hypoplasia and ectopia cardis were found in increasing order from acute to sub-acute exposure groups. The 50% fetuses from dose groups 75.00 mg/kg B.W. and 40% from dose group 37.50 mg/kg B.W. displayed decreased ossification as compared with control and vehicle control groups. Fetuses recovered from a group which was given garlic extract along with sodium arsenate exhibited normal development of fetuses except few dead embryos. In this group, fetal body weight, head and eye circumference, limb size and tail length were recorded as normal as controls and vehicle controls. Histologically, dose group 75.00 mg/kg B.W. of sodium arsenate in conjunction with 125 mg/kg B.W. Garlic extract exhibited enlarged ventricles of brain, however, 18.25 and 37.50 mg/kg B.W. + 125 mg/kg B.W. of garlic was observed near to controls and vehicle controls. Based upon the current results, we deduced that sodium arsenate had the potential to induce teratogenic effects in mammals and garlic extract might be a helpful tool against sodium arsenate induced fetotoxicity. There must be some stringent parameters followed by the industries for disposal of arsenate, so that arsenate concentration in drinking water could be managed to avoid exposure to expectant mammals especially the humans.