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Positional Cloning of Dfnb48 and Dfnb73 Loci

Thesis Info

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Author

Saima Anwar

Program

PhD

Institute

University of the Punjab

City

Lahore

Province

Punjab

Country

Pakistan

Thesis Completing Year

2009

Thesis Completion Status

Completed

Subject

Natural Sciences

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/6255/1/4036H.pdf

Added

2021-02-17 19:49:13

Modified

2023-01-08 08:35:08

ARI ID

1676726972179

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بھٹو کی شہادت کی پرسہ داری

بھٹو کی شہادت کی پرسہ داری

                                                                                                                زوار حسین کامریڈ

میری والدہ خورشید بیگم نے ستر کی انتخابی مہم میں قائد عوام کی جیت کے لیے مجھے بارہ سال کی عمر میں ساتھ لے جا کر گلی گلی خواتین میں پی پی پی کی کینوینسنگ جس جوش و جذبہ سے کی تھی اس کے محرکات سیاسی سے زیاددہ شیعہ عقیدہ سے وابستگی تھی ۔ان کے مطابق چئیر مین پی پی پی ذوالفقار علی بھٹو مولا علی کی تلوا ر ذوالفقار سے منسوب ہے جبکہ انتخابی نشان تلوار بھی تلوارِ حیدر کی علامت ہے ۔ ضیاء نے آمریت نافذکی تو امی نے اسے یزید ثانی قرار دے کر شہید بھٹو کے حق میں احتجاج کر نے کو امام حسین ؑ کی عزاداری کے برابر کا رتبہ دے کر مجھے ہر جلسے جلوس میں شرکت کا حکم دیا شہید ذوالفقار علی بھٹو اور پی پی پی پر ٹوٹنے والے مصائب کے ایام امی جان اور مجھ پر گھریلو مشکلات کا بد ترین دور لے کر آئے ۔جس کی وجہ والد صاحب کی تین شادیاں اور اس کے نتیجہ میں آ نے والی معاشی تنزلی تھی ۔جس سے میری تعلیم بری طرح متاثر ہوئی ۔گھر کا سیٹ اپ کچھ یوں تھا کہ میری امی سمیت تیسری والدہ شیعہ مسلک سے تھیں اور دونوں ایک ہی گھر میں مقیم تھیں ۔۔جہاں محرم کی عزاداری حد درجہ عقیدت اور غم و رنج میں ڈوب کر منائی جاتی تھی جبکہ میری بڑی والدہ محترمہ اہل سنت مسلک کی تھیں اور بچوں کو دینی تعلیم دیتی تھیں ۔ان کے ہمراہ رہنے والے بڑے بھائی اور دو بہنیں بھی سنی عقیدہ کی تھیں ۔فیملی کے حالات 1979ء کے اوائل تک اس نہج پر پہنچ گئے کہ مجھے اپنا گھر چھوڑ کر بڑی والدہ کے گھر منتقل ہو نا...

Relationship Between Service Quality and Customer Delight and Customer Loyalty at the Fitness Center Business in East Java

This article aims to analyze the relationship between Service Quality and Customer Delight and Customer Loyalty at the Fitness Center Business in East Java. This research method This research is an explanatory research. The unit of analysis in this study is the individual. The respondents of this research are members of the Fitness Center in East Java. The population in this study were all fitness members in the East Java region who during 2019-2020 years extended their membership at least twice and were in East Java, especially the Kartosusilo Gate area which includes the cities of Gresik, Bangkalan, Mojokerto, Surabaya, Sidoarjo and Lamongan. The number of sufficient samples is 365 respondents. The results show that Service Quality has no significant effect on customer delight. This is because with standard equipment and services, members feel happy. Likewise, the characteristics of the majority of fitness center members are individuals who feel quite happy with the situation and conditions provided by the manager, thereby indicating that the Service Quality at the current Fitness Center business in East Java has not been able to encourage an increase in customer delight. The results of this study also show that Service Quality has a significant effect on Customer Loyality, thus Service Quality at the current Fitness Center business in East Java can encourage the increase in Customer Loyality. Given the large role of service quality on customer loyalty, it is recommended that companies always maintain and improve service quality at the Fitness Center business in East Java.

One Year Symptom Severity and Health-Related Quality of Life Changes Among Patients Undergoing Uterine Fibroid Embolisation

Background: The main aim of treatment of symptomatic fibroids by various modalities including uterine fibroid embolisation is to alleviate symptoms and ultimately improve the quality of life. The efficacy of this modality of treatment in women with significant fibroid burden and large uterine volumes is not clear. Objective: To determine the change in symptom severity and health-related quality of life among patients who have undergone uterine fibroid embolisation for treatment of symptomatic uterine fibroids. Setting: Aga Khan University Hospital, Nairobi Methods: A prospective before and after study (observational) of patients undergoing uterine fibroid embolisation. Prior to embolisation, study participants underwent a pelvic MRI and filled in the Uterine Fibroid Symptom and Quality of Life questionnaire (UFS-QoL), a disease-specific symptom and health-related quality of life questionnaire for fibroids. The same questionnaire was administered after one year. Outcome measures: The main outcome was change in symptom severity score. Secondary outcome measures were change in health-related quality of life (HRQoL) score, the correlation between age, parity, uterine volume, fibroid number and change in the symptom severity and health-related quality of life scores and the incidence of an additional intervention. Results: Data from 80 study participants were included in the analysis. The mean change (improvement) in the symptom severity score was -29.6(SD±27.1) [95% CI -35.6 to -23.6, P<0.001] with a mean change (improvement) in health-related quality of life score of 35.7(SD±32.7) [95% CI 28.4 to 42.9, P<0.001].There was a significant positive correlation between fibroid number and change in symptom severity score. There was no significant correlation between age, parity, uterine volume and change in symptom severity score. There was a significant positive correlation between parity and change in the health-related quality of life score. There was no significant correlation between age, uterine volume, fibroid number and change in the health-related quality of life score. The incidence of a major and minor surgical intervention during the one year follow-up period was 6.25% and 12.5% respectively.iv Conclusions: UFE is associated with a statistically significant and clinically useful improvement in symptom severity and health-related quality of life in women with symptomatic fibroid disease and is an effective treatment option of symptomatic fibroids in patients with large myoma burden or large uterine volumes.