The present study was conducted to determine the effect of α-lipoic acid, α-tocopherol and wheat germ oil on the status of antioxidants, quality and lipid stability of broiler meat and meat product. One day old (180) broilers were fed with different feeds containing antioxidants i.e natural and synthetic α-tocopherol and α-lipoic acid during the two experimental years (2010- 12). The feed treatments possessed significant variation in the body weight gain and FCR while no influence found on the feed intake. The broilers fed on wheat germ oil (natural α-tocopherol) gained maximum weight (2451.97g & 2466.07g) during the experimental years 2010-11 & 2011-12, respectively. Total phenolic contents, DPPH and ferric reducing antioxidant power of breast and leg broiler meat differed significantly due to different feed treatments. Total phenolic contents were found higher in the broilers fed on T 5 (natural α-tocopherol and α-lipoic acid) in breast meat (162.73mg GAE/100g & 162.18mg GAE/100g) and leg meat (149.67mg GAE/100g & 146.07mg GAE/100g) during the experimental years 2010-11 & 2011-12, respectively. The DPPH and ferric reducing antioxidant power assay were also found higher in breast and leg meat fed on T 5 (natural α-tocopherol and α-lipoic acid). The production of malondialdehydes in the breast and leg meat increased with progressive increase in the time period. The deposition of α-tocopherol (AT) and α-lipoic acid (ALA) contents were found higher in the broilers fed on T 5 (natural α-tocopherol and α-lipoic acid) in breast and leg meat during both experimental years. The composition of saturated and unsaturated fatty acids in the breast and the leg meat of the broilers were significantly affected by different feed treatments. The antioxidant enzymes and the serum bio-chemical profile were also influenced statistically by the feed treatments. The total cholesterol (113.42mg/dL & 113.62 mg/dL) and triglycerides (52.29 mg/dL & 49.19mg/dL) were found the lowest in broilers fed on T 5 (natural α-tocopherol and α-lipoic acid) during the experimental years 2010-11 and 2011-12, respectively. The physico-chemical analysis of the nuggets showed that the feed treatments exerted significant effect on the pH, color, water activity, texture and TBARS of the nuggets made during storage. The feed treatments exhibited significant effect on the appearance, flavor, taste and overall acceptability of the nuggets during storage. The combination of natural and synthetic antioxidants in feed are more beneficial in increasing the antioxidant potential, stability and the quality of the broiler meat and also helped in lowering the cholesterol level and improves the polyunsaturated fatty acid profile of the broiler meat.