ملا طاہر سیف الدین
گذشتہ دو مہینوں میں مسلمانوں کے دو بڑے قومی حادثے ہوئے، ۵؍ نومبر کو داؤدی بوہرون کے امام ملا طاہر سیف الدین نے انتقال کیا، ان کی ذات جامع صفات تھی، بڑے ذی علم، دیندار، فیاض و مخیر اور وسیع القلب تھے، دینی علوم پر ان کی نگاہ بہت وسیع تھی، اس لحاظ سے وہ ہندوستان کے ممتاز علماء میں تھے، صاحبِ قلم بھی تھے، عربی میں ان کی کئی تصانیف ہیں، انھوں نے اپنے دور میں نہ صرف اپنے فرقہ کی بڑی تعلیمی و اقتصادی خدمت کی بلکہ دوسرے اسلامی فرقوں کے ساتھ بھی ان کا سلوک روادرانہ و فیاضانہ تھا، اور ان کو ایک دوسرے کے قریب لانے کی کوشش کی، مسلم یونیورسٹی کے تو چانسلر ہی تھے، اس کو وقتاً فوقتاً بڑی بڑی رقمیں دیتے رہتے تھے، دارالمصنفین کی جوبلی کے موقع پر اس کو بارہ ہزار کا عطیہ دیا، اس لیے ہر فرقہ کے مسلمانوں میں عزت و وقعت کی نظر سے دیکھے جاتے تھے، اﷲ تعالیٰ ان کے حسنات کے طفیل میں ان کی مغفرت فرمائے، دارالمصنفین اس حادثہ میں ان کے لائق جانشین ملا برہان الدین کا شریک غم ہے اور دعا ہے کہ خدا ان کو ان کے باعظمت والد کے نقش قدم پر چلنے کی توفیق عطا فرمائے۔ (شاہ معین الدین ندوی، دسمبر ۱۹۶۵ء)
Chronic Liver Disease (CLD) progresses from hepatocyte inflammation to fibrosis, regeneration, cirrhosis and in some cases to Hepatocellular Carcinoma (HCC). In general, the main etiologies of Liver Cirrhosis (LC) are viral infections (hepatitis C and B viruses), chronic alcohol abuse and Non-Alcoholic Fatty Liver Disease (NAFLD), including Non-Alcoholic SteatoHepatitis (NASH). Major complications of CLD are ascites, upper gastrointestinal bleeding, jaundice (acute or chronic) and hepatic encephalopathy. Objectives: This study assesses the etiological factors and complications of CLDin a tertiary care hospital of Lahore, Pakistan. Study Design: Cross-sectional. Methods: Study was carried out in indoor and Accident & Emergency Departments of Mayo Hospital Lahore. 100 clinically diagnosed CLD cases were chosen through “Convenient Sampling” technique during 3 months. Observations: Most common complications of CLD were upper GI variceal Bleeding (48%) & hepatic encephalopathy (34%) and acute or chronic hepatitis (AVH) (33%). Other less common complications observed were hepatorenal syndrome (10%), Spontaneous bacterial peritonitis (15%), Ascites (5%) and HCC (10%). Conclusions: Hepatitis C was found as main etiological factor of CLD. Bleeding andhepatic encephalopathy are the common complications. Awareness programmes regarding CLD and its complications are mandatory in our society to improve human health.
This dissertation communicates the results of a scientific endeavor undertaken for exploring the diversity of Basidiomycetous fungi of District Malakand, Pakistan. The District Malakand is an administrative unit of the Khyber Pakhtunkhwa province, occupies 952 Km2 land within the geographical limits of 34⁰ 35’ to 34⁰ 66’ N and 71⁰ 65’ to 72⁰ 25’ E. Collections of mushrooms, rust and smut fungi were made from different area of Malakand District during the years 2013 and 2014. Field data of the specimens were recorded on the spot, proper photographs were taken and the collection was dried and preserved accordingly. More than 150 specimens of Basidiomycota were collected, comprising of 51 taxa belonging to 17 families. Distribution pattern of the groups shows that Agaricomycotina, the mushroom forming fungi, was the largest group represented by 39 species, Pucciniomycotina, the pathogenic rust fungi by 11 species and the smut fungi, Ustilaginomycotina, with a single species viz., Urocystis avenastri. All these fungi were characterized morpho-anatomically. The members of Agaricomycotina were also subjected to molecular identification, based on four gene regions viz., ITS, nrLSU, rpb2, tef-1α. Phylogenies of the analyzed taxa were elaborated with maximum likelihood, maximum parsimony and Bayesian analysis. Our research outputs includes one new species to science viz., Tulotoma ahmadii. Ten more taxa viz., Agaricus malakandensis nom. prov., A. minorus nom. prov., Cantharocybe pakistanicus nom. prov., Coprinopsis hispidus nom. prov., Hymenagaricus pakistaniensis nom. prov., Leucoagaricus badius nom. prov., La. xiii sultanii nom. prov., Parasola lentiformis nom. prov., Pa. malakandensis nom. prov. and Psathyrella fusiformis nom. prov., are in the process of recognition / publication as new species. Furthermore, other 12 species viz., Agrocybe semiorbicularis, Conocybe papillata, Coprinellus curtus, Marasmiellus palmivorus, Pleurotus cystidiosus, Parasola lilatincta, Pa. schroeterii, Stropharia ambigua, Puccinia microspora, P. nakanishikii, Termitomyces umkowaan and Trametes lactinea are added as new records to the species list of the fungi of Pakistan. In Agaricomycotina, Agaricaceae proved to be the most frequent family represented by six genera (Agaricus, Hymenagaricus, Leucoagaricus, Leucocoprinus, Lycoperdon and Tulostoma). The second largest family was Psathyrellaceae with four genera viz., Coprinellus, Coprinopsis, Parasola and Psathyrella. Only two genera were recorded for each the family i.e., Omphalotaceae, Polyporaceae and Strophariaceae. Whereas families like Bolbitaceae, Hygrophoraceae, Hymenocheataceae, Geastraceae, Lyophyllaceae, Miripelaceae, Mirulaceae, Pleurotaceae and Pluteaceae were represented by a single genus each i.e., Conocybe, Cantharocybe, Phillanus, Geastrum, Termitomyces, Rigidoporus, Irpex, Pleurotus and Volvariella, respectively. Pucciniomycotina was represented by two families, Phragmidiaceae (Phragmidium) and Puccineaceae represented by (Puccinia, Uromyces). The Ustiloginomycotina was monotypic only represented by Urocystis avenastri. This study concluded that low altitude mountains, foothills and grassy lands of Malakand are rich in fungi species and needs exploration of other groups also. These findings have not only upgraded the existing knowledge of basidiomycetes Mycota from District Malakand but also established a sound baseline for future research and exploitation of fungi in Pakistan.