Research was carried out on an important pest such as M. graminicola of cereal crop. In Pakistan the yield of wheat is extremely low as compared to many other developing countries. Among many factors, responsible for low crops yield but M. graminicola is an emerging threat. Infestation of Meloidogyne graminicola in wheat was recorded at various location of Faisalabad, Punjab, Pakistan. Data were recorded on disease incidence, severity and relative frequency of root infestation. The disease incidence % of the nematode was maximum in Uaf and minimum in Jhumraha. The disease severity % of the nematode was maximums in Jaranwala and minimum in Khurianwala. The relative frequency % of the nematode was maximum in Uaf and minimum in Khurianwala. Development of M. graminicola was assessed on alternate hosts inculding soyabean, brinjal and tomato by inoculating after 30 days. Maximum development of M. graminicola was recorded in brinjal followed by tomato and soyabean. Screening of wheat germplasm was done for its resistance against M. graminicola in three set of experiments including green house, microplots and field level. Data was recorded on plant growth and nematode reproduction parameters. Variety response was varied six varieties were found highly susceptible, seven susceptible and five resistance against this nematode.In vitro and vivo M. graminicola was tested most susceptible variety (Aus -7-58-0850) and number of juvenile maximum. The maximum juvenile mortality was done by plant extract neem by using S concentration. The maximum egg hatching was done by plant extract such as clove by using S concentration. These studies were helpful for management of M. graminicola.