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Synthesis and Characterization of Organotin Iv Complexes With Donor Ligands

Thesis Info

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Author

Gora, Wajid Rehman

Program

PhD

Institute

Gomal University

City

Dera Ismail Khan

Province

KPK

Country

Pakistan

Thesis Completing Year

2005

Thesis Completion Status

Completed

Subject

Chemistry

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/3128/1/745.pdf

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676727458312

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Organotin(/V) complexes with the general formulae R"SnL4''n and R,,sn2L,, ( R= alkyl, L = monomethyl glUlarate, monomethyl phthalate, monomethyl (2-phenyl gllllarate) and SchifJbases of2-aminophenol and salicylaldehyde) have been prepared. These complexes have been synthesized by the reaction of organolin(lV) halides with ligand in the presence of a base. Further, some diorganolin(iV) complexes have been synthesized by the reaction of organotin(lV) oxide with the ligand. The reaction Is carried OUi at the reflux temperature of benzene while water formed during the reaction is cont/nuously removed by means of a Dean alld Stark apparatus, The reactioll of organotln(lV) oxides with organic acids is more economical and gives beller purities as the reaction of organotin(lV) haUdes with organiC acid, in the presence of a base. These complexes have been characterized by elemental analyses and molar condut''livily The chemical bondings in these complexes have been discussed in terms of their JR. i 11-, and il9Sn-NMR, mass and I19Sn-lvfossbauer spec/ral studies, The I II and 1JC chemical shift assignments of the organotin moiely are straightforward from the mulliplicity and illlensity pal/ern, whereas the ligand skelelons were assigned by multiplicity pal/ern and I or resonance inlensilies of signals as well as their coupling conSlanls, The alkyl groups aI/ached to the Iin(l~J atom have been assigned by Ihe comparison of experimental chemical shifts with those calculated from incremelllal methods or compared to Ihe liIeralUre dala, The monomeric I: 1 complexes have trigonal bipyramidal geometry with equilorial organic groups. the dimeric /, complexes have ocl(liledr(ll geometry while complexes derived .from a Schiff base of 2-aminphenol and salicylaldehyde have tetrahedral geometries. Mass spectrum analyses reveallhal Ihe primary decomposition is due 10 the loss of a ligand in case of diorganotin(l V) complexes along with Ihe successive elimination of a C02 molecule while in Iriorganotin(IV) complexes Ihe primary decomposition is due /0 the loss of an alkyl group along with Ihe elimination of a CO, molecule, III The geometry assigned 10 Ihese complexes is well supported by infrared and Mossbauer silldies, All these complexes, soluble in DMSO and DMF have been screened against a wide spectrum of bacleria (Bacillus sublilh Slapholococcus aureus, Escherichia coli, Schigella flexenari, Pseudomonas aeruginosa, and Salmonella typh) and fungi (C.copsici, C.glocosporiodes, A, brassicico/a, A, bra5sicae, !/. graminium, The ALDso values have been determined with albino ralS, Some oflhe complexes exhibited very high anti-inflammatory activities, The cylostalic activity of the complexes has been assayed aga/nsf the established cell line KB, which has been derived from a human oral epidermoid carcinoma, The results obtained are qllile promiSing Overall, triorganotin(lV) derivatives exhibit signt{icanlly beller activilies than fhe diorganolin(JV) complexes,
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والدہ، ڈاکٹر جوہر قاضی

ڈاکٹر جوہر قاضی والدہ
تعزیت
رُکن مجلسِ ادارت اعزازی ماہنامہ برہان ڈاکٹر جوہر قاضی کی والدہ محترمہ ۵؍ جولائی ۱۹۹۷ء کو شنبہ کی صبح مختصر علالت کے بعد دہلی میں اپنی رہائش گاہ پر انتقال کرگئیں۔انا ﷲ وانا الیہ راجعون۔
مرحومہ کی عمر تقریباً پچھترسال تھی۔ وہ ایک دین دار خاتون تھیں۔ان کی وفات بلاشبہ ڈاکٹر جوہر قاضی،اہل خاندان اوران کے رفیق سفر جناب حکیم قاضی محمدیٰسین عالم صاحب مدیر اعلیٰ ماہنامہ ’راحت وصحت‘ کے لیے ایک عظیم صدمہ ہے۔ میں اپنی طرف سے اور کارکنانِ ادارہ کی طرف سے دعا کرتا ہوں کہ اﷲ تعالیٰ مرحومہ کواپنے جوار رحمت میں جگہ دے اور لواحقین کو صبرجمیل عطا فرمائے۔
ہم جناب ڈاکٹر جوہرقاضی اوران کے اہل خاندان کے اس غم میں برابر کے شریک ہیں۔مجھے بذاتِ خوداس سانحۂ ارتحال سے سخت جھٹکا لگاہے۔
[عمیدالرحمن عثمانی،جولائی واگست ۱۹۹۷ء]

 

بائبل اور اسلام کی روشنی میں عورت کا مقام اور کردار

Status and role of  woman has been discussed in almost every religion. A considerable portion of the  Scriptures of  Sematic religions  also addressed issues regarding woman in one way or another. In the light of the teachings of the Bible Woman is a  sign of sin, cleverness, social injustice and  violence. On the other hand Islam gave  woman more recognition and freedom of choice regarding   marriage, , education, inheritance,   etc. Islam believes in the equality of  male and female and as a result in Islamic society  woman has been  enjoying a better status and position. In this article a comparison of the role and status  of a woman has been discussed in the light of Bible and Islam.

Influence of Strigolactone Gr24 on Growth, Physiological and Biochemical Attributes of Wheat Triticum Aestivum L. under Saline Conditions

In order to examine whether exogenous application of strigolactones (GR24) could mitigate the adverse effects of salt stress on spring wheat (Triticum aestivum L.), experiments were conducted under natural climatic conditions in a net-house of the Old Botanical Garden, University of Agricuture, Faisalabad Pakistan. Both wheat cultivars [S-24 (salt tolerant cultivar) and PARI-73 (moderately salt sensitive cultivar)] were grown in full strength Hoagland’s nutrient solution under non-stressed and salt stressed conditions. Experiment I was conducted to explore the effect of pre-seed treatment with strigolactone (GR24) for 16 h. on wheat under non-saline and saline conditions. There were four different levels of GR24 solution (Water (0), 0.001, 0.01 and 0.1 mg L-1). Salinity treatment applied through root growing medium to fifty day-old plants. There were two salt (NaCl) levels control (0 mM) and 150 mM (NaCl). Experimental design was completely randomized with four replicates. Data were recorded of 77 day old plants. In experiment I findings, root growing salinity (150 mM) significantly decreased growth attributes, photosynthetic efficiency of wheat plants, leaf water relations parameters except leaf turgor potential, activity of catalase enzyme, shoot and root K+ and shoot Ca2+ and yield attributes except 100-seed weight. However, concentration of ascorbic acid, activity of glutathione reductase, production of hydrogen peroxide, accumulation of organic osmotica (Proline and glycinebetaine contents) and uptake of shoot and root Na+ ion contents significantly increased under salt stress. Pre-soaking seed treatment with GR24 increased photosynthetic efficiency, only leaf water potential, enzymatic antioxidants (catalase and peroxidase) activities, accumulation of total soluble proteins, osmoprotectants like proline and glycinebetaine contents, non-enzymatic antioxidants (total phenolic contents and glutathione reductase activity) and production of hydrogen peroxide. Pre-soaking seed treatment with GR24 further slightly reduced growth and number of tillers per plant. Exogenous application of GR24 in experiment II was applied through foliar spray. In experiment II, imposition of salinity through root growing medium (150 mM) significantly reduced growth parameters, non-photochemical quenching (NPQ), electron transport rate (ETR) and co-efficient of non-photochemical quenching (qN), gas exchange characteristics, water relations parameters, ascorbic acid contents and shoot and root K+ and Ca2+ ions. Salinity increased accumulation of glycinebetaine and free proline, activities of enzymatic antioxidants and Na+ contents in both shoot and root of wheat plants. GR24 spray XV significantly increased gas exchange characteristics except transpiration rate (E), activities of enzymatic antioxidant, accumulation of free proline production but markedly increased the malondialdehyde and hydrogen peroxide (H2O2), root Ca2+ and K+ content. Overall, S-24 performed better than PARI-73 in all aspects and PARI-73 severely affected by salinity.