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Synthesis Characterization and Biological Applications of Copper and Silver Complexes of Coumarin Based Ligands

Thesis Info

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Author

Zulfiqar Ali

Program

PhD

Institute

University of Engineering and Technology

City

Lahore

Province

Punjab

Country

Pakistan

Thesis Completing Year

2015

Thesis Completion Status

Completed

Subject

Chemistry

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/13272/1/Zulfiqar_Ali_Chemistry_2015_UET_Lahore_10.06.2016.pdf

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676727476645

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This research work is based on synthesis of various coumarin derivatives and structure of those derivatives were confirmed by using different spectroscopic techniques like IR, λmax, 1H NMR, 13C NMR ESI-MS etc. These derivatives were then utilized to make different metal complexes with Cu and Ag metals. The synthesized complexes were then characterized by using IR, atomic absorption; thermal gravimetric analysis, powder XRD, mass spectrometry and their magnetic properties were also studied by VSM. Finally coumarin and coumarin derivatives and all metal complexes (M= Cu, Ag) were used against different pathogens to study their antibacterial activity. All coumarin derivatives and metal complexes shown antibacterial activity against any one of the bacterial strain and inhibited their growth.Metal complexes found to be more efficient against bacterial strains than coumarin ligands.
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