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Synthesis of Piperidine Derivatives Having Potential Therapeutic Properties

Thesis Info

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Author

Saeed, Mohmmad

Program

PhD

Institute

University of Karachi

City

Karachi

Province

Sindh

Country

Pakistan

Thesis Completing Year

1994

Thesis Completion Status

Completed

Subject

Chemistry

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/4594/1/968.pdf

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676727493069

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مسجدِ صحابہ

مسجدِ صحابہ

شام سمے ہماری گاڑی طریق السلام پر فراٹے بھر رہی تھی ۔شدید گرمی سے لوگوں کے چہروں کو لال کر نے والا سورج بحیرہ احمر میں ڈبکی مارنے کی تیاری کر رہا تھا۔ساتھ والی نشست پر بیٹھی دکتورہ شائمہ سے میں نے پوچھا ہم کہاں جا رہے ہیں ۔اس نے کہا ’’مسجدِ صحابہ ‘‘بہت خوبصورت مسجد ہے ۔میں نے پوچھا کوئی پرانی مسجد ہے کہنے لگیں زیادہ پرانی نہیں مگر عمارت شاندار ہے ۔چند کلومیٹر راستہ طے کرنے کے بعد بلند میناروں والی مسجد صحابہ کے بلند وبالا گنبد و مینار اپنی عظمت کا احساس دلا رہے تھے ۔صحرائے سینا کی ریت کی مانند زرد بھوری مائل خشت اور ریختے سے بنی یہ مسجد ایک خوبصورت دلہن کی طرح سجی نظر آ رہی تھی ۔ دکتورہ شائمہ کے بہ قول اس مسجد کی بنیاد ۲۰۱۱ء میں رکھی گئی ۔مگر ملکی سیاسی حالات میں اتار چڑھائو کی وجہ سے تعمیراتی کام تسلسل کے ساتھ جاری نہ رہا ۔اس مسجد کا نقشہ ایک مصری آرکیٹیکٹ فواد توفیق نے بنایا ،نقشے کو ترتیب دیتے وقت فواد توفیق نے مصر پر حکمرانی کر نے والے تین مسلم ادوار فاطمی ،مملوکی اور عثمانی کو مدِ نظر رکھا ۔مسجد کے دو طویل القامت مینار اور کئی گنبد دیکھنے والوں کی آنکھوں کو خیرہ کرنے میں کوئی کسراٹھا نہیں  رکھتے ، مسجد کے صحن میں سیمنٹ اور گارے سے بنے خوبصورت پانی کے جھکے ہوئے مٹکے جن میں لگی برقی موٹروں کے ذریعے قریبی گملوں اور کیاریوں میں موجود پودوں اور پھلوں کو سیراب کیے جانے کا دلکش منظر دیکھ کر سیاح اپنے موبائل کیمروں میں اس کی عکس بندی میں مصروف تھے ۔دکتورہ بسنت نے مجھ سے پوچھا کہ ’’آپ مسجد کے اندر جائیں گے ؟‘‘ میں نے کہا جی ضرور ۔انھوں نے مجھے دکتورخالد ،دکتورہ شائمہ کے...

The Concept of Medical Treatment and Guidelines for Physicians in Islamic Perspective

In fact, good health is the ultimate end of medicine for everyone through medical treatment. Islam does approve necessary measures to sustain good health. Thus its sustenance senses the subjects to avoid undue pains and sufferings. For this purpose medications and medical treatment is measured as a recognized tool in Islamic law. Therefore, this research paper reveals that numerous Muslim scientists worked on different branches of science,  and hence the Muslim physicians execute one of the most complicated “eye surgery” almost six hundred (600) years earlier than the European physicians. Indeed, it is the Muslim scientists who discovered the ‘force of gravity’, ‘blood circulation’, ‘laws of motion’. Factually, they developed the ‘theory of evolution’, ‘differential and integral mathematics’ and many more in the field of science. Consequently, the words of Campbell in this regard are very important to note that: “the European medical system is Arabian not only in origin but also in its structure”, which signify that “Muslim scientists are directly responsible for the European renaissance”. Resultantly, this paper argues that ‘medical treatment is an obligation if one’s life is in danger’ since preservation and protection of life is one of the primary objectives of Shariah. Although, in extraordinary circumstances, seeking medical treatment is highly encouraged in Islam, and an ill person is supposed to pursue medical treatment because Allah almighty has made both the illness and the cure.

Immobilization of Nickel in Industrial Contaminated Soil Using Organic and Inorganic Amendments

Nickel (Ni) bioavailability in the soil can be alleviated by the integrated use of immobilizing agents. In the current study, it was observed that sole of combined use of biochar (BA), zeolite (ZT) and gravel sludge (GE) significantly influenced the Ni bioavailability in Ni stimulated soil compared to control. The bioavailable Ni contents were measured in DTPA, Ca(NO3)2 and extracts and soil water extract (SWE) with indicator plant red clover (Trifolium pratense L.). The impact of immobilizing agents and a bioavailable portion of Ni was assessed through physiology, growth and biochemical characters of red clover were recorded. Results showed that application of ZT significantly decreased the extractable Ni concentrations in all treatments, however, the combined use of BA and ZT significantly reduced the Ni and decreased the generation of (ROS) thus positively influence physiological, agronomic and biochemical attributes of red clover. Therefore, ZT and BA as sole or combination of both were selected the second experiment with the object to immobilize Ni in soil with both maize and sunflower as a test crop. Results revealed the treatment receiving ZT: BA with 1:3 significantly improved the growth, yield, chemical and biochemical attributes in both crops over control. Nickel-induced oxidative stress was significantly mitigated in this treatment compared to control. However, the highest decrease in uptake of Ni was observed where ZT: BA was 1:1 compared to control. Based on finds of the second study, the third study was designed with ZT: BA 1:1 selected from the previous study. Wheat (Triticum aestivum L.) grown and proline (PO) was exogenously applied according to the treatment plan. Proline acts as a stress alleviator and mitigates heavy metals stress. Proline was applied with ZT: BA 1:1 mixture to determine the efficiency of these amendments and PO to mitigate Ni stress and improvement in antioxidants activity in wheat. The finding suggested that the combined use of immobilizing agents with some stress alleviator could significantly reduce Ni bioavailability and increased the biomass, physiological and biochemical parameters. Ni induced oxidative stress was also ameliorated in wheat with ZT, BA, and PO, compared to control.