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The Genetics of Nephrotic Syndrome in Pakistani Children

Thesis Info

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Author

Shahid, Saba

Program

PhD

Institute

Sindh Institute of Urology and Transplantation

City

Karachi

Province

Sindh

Country

Pakistan

Thesis Completing Year

2013

Thesis Completion Status

Completed

Subject

Applied Sciences

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/2321/1/2536S.pdf

Added

2021-02-17 19:49:13

Modified

2023-01-06 19:20:37

ARI ID

1676727579629

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مولانا حافظ محمد اسلم جیراج پوری

مولانا حافظ محمد اسلم جیراج پوری
افسوس ہے مولانا حافظ محمد اسلم جیراج پوری بھی جو علم وادب کی صبح بہار کا ایک آخری جلوۂ گریز پاتھے۔ہم سے بچھڑ گئے اوراس خاکدانِ آب و گل کو خیرآباد کہہ کر رہ گزائے عالم آخرت ہوگئے۔مرحوم ہماری بزم علم وثقافت کے دور پیشین کی یادگار تھے۔ایک زمانہ میں اُن کے مضامین ومقالات کابڑاچرچا تھا۔ باقاعدہ اور وسیع المطالعہ عالم تھے۔ان کی تالیفات میں’تاریخ الامت‘ جو چھوٹی چھوٹی کئی جلدوں میں ہے اس کوبڑی شہرت ومقبولیت حاصل ہوئی۔اس کے علاوہ چند ادبی اور تنقیدی مضامین اورسوانحی تالیفات بھی ان کی یادگار ہیں۔جامعہ ملیہ اسلامیہ کے اولین معماروں اوربانیوں میں سے تھے اورآخر اسی کی خدمت کرتے کرتے جان جان آفرین کوسپردکری۔قرآن مجید کے ساتھ بڑاعشق اورشغف تھا، اس کے وہ حافظ بھی تھے اوربڑی پابندی سے روزاس کی تلاوت کرتے تھے۔ نہایت سادہ زندگی بسر کرتے تھے۔راقم الحروف کوجب کبھی ان کے ہاں چائے پینے کا اتفاق ہواہے کبھی بھی ایسا نہیں ہواکہ چائے کی پیالیاں صحیح وسالم پائی ہوں۔ بڑے قناعت پسند،گوشہ نشین،شہرت سے نفوراور حددرجہ متواضع اورمنکسر المزاج بزرگ تھے، جس سے جو وضع تھی بہرحال نباہتے تھے۔ حدیث کے بارے میں ان کا جو مسلک تھا اس کے باوجود ہم ارباب ندوۃالمصنفین کے ساتھ ان کے تعلقات بڑے شگفتہ تھے اور وہ کبھی نجی ملاقاتوں میں اس طرح کی بحث نہیں اُٹھاتے تھے۔یہ وضع داری اورشرافت،یہ مروت اورخوش خلقی اب عنقا ہوتی جارہی ہے۔اب آئندہ ایسے لوگ کہاں ملیں گے۔اﷲ تعالیٰ ان کو غریق رحمت فرمائے اور ان کو مغفرت وبخشش کی نعمتوں سے سرفراز فرمائے۔آمین
[جنوری ۱۹۵۶ء]

 

CORRELATION OF MYOFASCIAL TRIGGER POINTS WITH UPPER LIMB DISABILITY IN POST MASTECTOMY FEMALES IN PAKISTAN

Aims of Study: The objective was to correlate myofascial trigger points and upper limb disability in post-mastectomy females. Methodology: This six-month duration study included 45 participants aged 18 or older, using non-probability convenience sampling, who had undergone mastectomy at least six months prior. Numeric pain rating scale, Simon’s trigger point criteria and a disability questionnaire were used to assess disease complications. Results: A study involving 45 female participants (mean age 42.8±6.754) found that 33.3% had mild pain, 55.6% had moderate pain, and 11.1% had severe pain. Additionally, 46.7% had mild disability and 53.3% had moderate disability. There was a significant correlation between myofascial trigger points and upper extremity disability. Limitations and Future Implication: The limitations include the small sample size used in study and limited generalization of findings due to cultural and contextual factors. Further research is needed to explore interventions and understand the long-term impact of myofascial trigger points on upper limb function. Originality: This research is original in its focus on the correlation between myofascial trigger points and post-mastectomy upper limb disability. Conclusion: This study concluded that there is a highly significant relation between trigger points in muscles and disability of upper extremity in female patients after mastectomy.

Boron Dynamics in Alkaline Calcareous Soils and its Availability under Wheat-Cotton Cropping System

Wheat (Triticum aestivum L.) is the world’s leading cereal crop and is unanimously consumed as staple food product of almost hundred percent Pakistani nationals as well as about 1/3 rd population of the world. Cotton (Gossypium hirsutum L.) is an important cash crop of Pakistan but the yields of wheat and cotton in Pakistan have been stagnated throughout the preceding decade due to improper fertilizer management and non- exploitation of micronutrients specially boron. Boron (B) is extraordinary amongst the microelements in that an extremely diminutive amount is required for ordinary growth and maturity of plants, and simply somewhat greater B concentrations are toxic. A three- year (2005-2008) study was initiated to determine the boron status of soils under wheat- cotton system and also to assess the relationship between soil B and physico-chemical properties of soils. B content present in canal and tubewell waters being used by wheat- cotton, were also assessed. The responses of cotton and wheat crops to foliar and soil applied B were also studied under field conditions. Almost all the soils were calcareous in nature (92 % area), alkaline in reaction (83 % area had pH > 8) and 100 % area had OM < 1 %. In case of soil B content, 82 % soils were deficient in B (0.10 to 0.45 μg g -1 ), 15 % were adequate (0.46 to 0.55 μg g -1 ) and only three samples were sufficient (0.56- 0.91 μg g -1 ). More B was observed in the fine textured soils (28 % area). Low B concentrations were observed in wheat and cotton plants. The average B concentrations during 2006 and 2007 in wheat leaves were 8.86 and 4.41 mg kg -1 , and in cotton 37.78 and 15.83 mg kg -1 . Mean B content in canal water was more during monsoon season (0.14±0.10 mg L -1 ) as compared to that during winter season (20±0.13 mg L -1 ), respectively. Whereas, B concentration was more in tubewell waters as compared to that in canal waters. B fractionation study revealed that the highest mean plant available B (0.32±0.12 mg kg -1 ) was obtained by hot water extraction followed by 0.05M HCl (0.31±0.12 mg kg -1 ), and 1:2 water extraction whereas the lowest B concentration was extracted by 0.005M DTPA. Total soil B content of all the soils varied from 15.61 to 152.80 mg kg -1 and it was further fractionated by using 0.05 M HCl (readily soluble B), 0.05 M KH 2 PO 4 (exchangeable B), 0.02 M HNO 3 -H 2 O 2 (extractable B), 0.25 M NH 4 - oxalate extractable B and the residual B. The highest mean B fraction was the residual fraction (70.50 mg kg -1 ) whereas the lowest was the water soluble B (0.33 mg kg -1 ). Field 15experiments were conducted at three different textured soils (loam, sandy clay loam and silt loam). Ten B treatments were applied to soil (0.00, 0.25, 0.50, 0.75, 1.00, 1.25, 1.50, 1.75, 2.00 and 3.00 kg B ha -1 at sowing along with recommended NPK fertilizers for -1 cotton and wheat. Whereas five B levels (0.00, 0.25, 0.50, 0.75 and 1.00 kg ha ) were used for foliar application in three replications in RCBD, while all other recommended nutrients for cotton and wheat were applied. Foliar sprays were performed on cotton before flowering, at flowering and at boll formation stages while on wheat before tillering, at booting and at milking stages. B application as soil and foliar sprays significantly increased the number of bolls, boll weight, lint, seed cotton, dry matter yield, lint percent, leaf B concentration and total B uptake. Foliar use of B (0.50 kg B ha - 1 ) increased the seed cotton yield by 25.60 % over control on loamy soil followed by that on silt loam soil (23.80 %), however during the next year (2007), seed cotton yield mildly decreased compared to first year at the same B application level of 0.50 kg B ha -1 but it remained significantly higher than control by 8 and 21.50 % at loam and silt loam soil (23.80 %), respectively. Likewise, wheat crop significantly responded to B application both as soil and foliar in terms of grain and straw yields, number of grains spike -1 , 1000- grain weight, plant height, plant B concentration and total B uptake while it had non- significant effects on tillering and protein content. B application improved the grain yield by around 6, 9.60 and 6 % at B application levels of 0.50, 0.75 and 1 kg ha -1 , respectively. Finally, the residual or carry-over study revealed significant responses of wheat crop to residual B applied to previous cotton crop. Residual B significantly improved the grain and straw yields, number of grains spike -1 , 1000-grain weight, plant height, plant B concentration and total B uptake and protein content of wheat. The highest and the lowest protein content of 14.54 and 11.17 % were obtained with residual B levels of 1.50 and 3 kg ha -1 , respectively.