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Automatic Colon Cancer Detection and Classi Cation

Thesis Info

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Author

Rathore, Saima

Program

PhD

Institute

Pakistan Institute of Engineering and Applied Sciences

City

Islamabad

Province

Islamabad

Country

Pakistan

Thesis Completing Year

2015

Thesis Completion Status

Completed

Subject

Computer Science

Language

English

Link

http://prr.hec.gov.pk/jspui/bitstream/123456789/6797/1/Saima_Rathore_Computer_Sciences_PIEAS_2015.pdf

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676727708700

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In the past two decades, automatic colon cancer detection has become an active research area. Traditionally, colon cancer is diagnosed using microscopic analysis of pathological tissue imagery. However, the process is subjective and leads to considerable inter/intra observer variation in diagnosis. Therefore, reliable computer-aided colon cancer diagnostic systems are in high demand. In this thesis, a computer-aided colon cancer diagnostic (CAD) system has been proposed that comprises three main phases. In therst phase, an unsupervised colon biopsy image segmentation technique, which is based on a few novel extensions in traditional object oriented texture analysis based segmentation technique, has been developed. The second phase deals with classi cation of colon image and gene based datasets into normal and malignant classes. For the colon biopsy image based datasets, two classi cation techniques based on hybridization of various features have been proposed. In these techniques, some traditional features such as morphological and texture, variants of traditional features, and some novel features which have especially been designed to capture the variation between normal and malignant colon tissues have been used. Similarly, for the gene expression based dataset, a novel technique that utilizes various feature selection strategies for solving the challenging problem of larger dimensionality of gene based datasets, and a weighted majority voting based ensemble of various SVM classi ers for performance improvement has been proposed. In the third phase of this work, the structural variation in the shape of lumen among various colon cancer grades has been quanti ed in terms of a few novel structural features. These features are used for the classi cation of malignant colon biopsy images into various cancer grades. Performance of the proposed diagnostic system has been validated on various datasets, and superior qualitative and quantitative performance has been observed compared to previously reported methods of colon cancer detection.
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دہشتگردی ایک المیہ ہے

دہشت گردی ایک المیّہ ہے
بھلا بے دخل ہو کیوں کر مکاں اپنے مکینوں سے
وہ دہشت گرد بن جاتے ہیں جن کے گھر نہیں رہتے
دہشت گردی کا لفظ گذشتہ چند سالوں سے ہمارے معاشرے میں اتنا استعمال ہونے لگا ہے کہ اس سے خوف و ہر اس کی کیفیت پیدا ہوگئی ہے۔ کیونکہ جس لفظ کے ساتھ اس کا لاحقہ اشتراک کرتا ہے وہ زیادہ نقصان دہ ہو جاتا ہے اگر یہ لفظ وکیل کے ساتھ استعمال ہوتو قانونی دہشت گردی، محلے کے ساتھ استعمال ہوتو محلاتی دہشت گردی ، لفظ دہشت گردی خوف و ہراس کی علامت بن چکا ہے۔ دہشت گردی ایک المیّہ ہے وہ معاشرہ، وہ قوم،وہ ملک جو پسماندگی کی کیفیت سے دو چار ہو اور کئی المیے جس کے حسن کو گہنا رہے ہوں ، اس کے استحکام کو متزلزل کر رہے ہوں۔ اس کی فلک بوس عمارتوں کو مسمار کر رہے ہوں تو وہ قابلِ رحم ملک ہے۔ ہمارے ہاں المیوں کا جم غفیر ہے جو ہمارے مسلم معاشرے کو بیخ و بن سے اکھاڑنے کے درپے ہیں۔ ہمارے ہاں عصبیت ایک المیہ ہے، اقربا پروری ایک المیہ ہے، کرپشن ایک المیہ ہے،رشوت ایک المیہ ہے۔ منافقت ایک المیہ ہے، بے جا مخالفت ایک المیہ ہے اور اس وقت جس نے ہماری کمرتوڑ کر رکھ دی ہے وہ مہنگائی کا المیہ ہے۔ ان سب المیوں سے زیادہ خطر ناک ، زیادہ ہیبت ناک ، زیادہ خوفناک ، زیادہ اندوہناک المیہ دہشتگردی کا ہے۔ یہ ایک ایسا المیہ ہے جس نے عوام الناس کا آرام و سکون برباد کر رکھا ہے۔ کوئی جان کسی حال میں بھی محفوظ نہیں ہے۔ گھر ، بازار مسجد ،مزار کوئی جگہ بھی محفوظ نہیں ہے۔
اسلام امن پسند مذہب ہے ،مکمل ضابطہ حیات ہے۔ اللہ تعالیٰ کا پسندیدہ دین ہے۔ امن وسلامتی...

مسلح تصادم کے دوران و ما بعد غیر مقاتلین کے حقوق

Islam is a religion of peace and values the sanctity of life and blood. It clearly prohibits unlawful killing. However,   it is also a  fact that observing this rule is very difficult during an armed conflict but still Islam has laid down  clear injunctions about this. It has divided the belligerent groups into combatants and non-combatants and the rights of each one has been mentioned. In this article the later has been discussed. In this regard verses from the Holy Qura’n, Traditions of the Prophet (PBUH) and views of the  jurists  have been quoted. All of them guarantee sanctity of life of non-combatants. At the end, relevant articles of the International Humanitarian Law (IHL) have also been quoted, which are in  consonance with the teachings of Islam.

An Evaluation of Impact of Monetary Policy on Economy of Pakistan

Objective of the study is to evaluate the impact of monetary policy on the economy of Pakistan in the light of Monetarist and Keynesian views. Keynesian argue that monetary policy is ineffective in stimulating the economic growth of a country, which is said to be determined by the economic growth levels of its large and developed trading partners. Money supply and inflation are considered to be insignificantly related to economic growth. It is further argued that the monetary authorities cannot control money supply changes as desired, namely, to keep them within the set money supply guidelines, because of foreign external forces flowing out of international trade conducted with these large and developed partners. By contrast, the monetarist counter-argument affirms the efficacy of the money supply and inflation in influencing the economic growth of a country. Monetary authorities are said to be capable of controlling money supply via the bank rate (repo rate), that the current level of money supply is significantly related to that of the previous period. By using forty year data, it is evaluated that impact of interest rate on economic growth is negative and at the same time its impact on unemployment is positive. It is also investigated that there exist tradeoff between inflation and unemployment. It is also estimated that current money supply strongly depends upon the money supply of previous period. Impact of monetary base and broad money on economic growth and on unemployment is very much weak near to zero. Saving is the component of aggregate savings and consumption is the necessary component of aggregate demand but it is evaluated that impact of saving on GDP growth rate is significantly positive as compare to consumption. So those policies should be used which are helpful to increase the saving in the xiv country. In the case study of Pakistan, the empirical findings confirm that the economic growth is not significantly related to changes in money supply and inflation but it is significantly related to the changes in real exchange rate and interest rate and that ability of monetary authorities to control money supply is constrained by external factors. While monetary policy is ineffective in controlling changes in the money supply, keeping it within set target limits or guidelines, it is able to influence the current level money supply by operating on that of the previous period.The Keynesian argument that the monetary authorities cannot control money supply changes, i.e. keeping them within set target guidelines, is confirmed. The basis of this argument is said to be the unfair terms of trade faced in dealing with large and developed countries. This is despite the significant relationship between the current level of money supply and that of the previous period.