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Home > Prevalence of and Factors Associated With Vitamin D Deficiency Among Afghan Adolescents Diagnosed at a Tertiary Healthcare Facility in Kabul, Afghanistan

Prevalence of and Factors Associated With Vitamin D Deficiency Among Afghan Adolescents Diagnosed at a Tertiary Healthcare Facility in Kabul, Afghanistan

Thesis Info

Author

Shabnam Azizi

Department

French Medical Institute for Children (FMIC)

Program

Diploma

Institute

Aga Khan University

Institute Type

Private

City

Karachi

Province

Sindh

Country

Pakistan

Thesis Completing Year

2017

Thesis Completion Status

Completed

Subject

Clinical Pathology

Language

English

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676727858534

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Background: Vitamin D, also known as the sunshine vitamin, is formed in the skin from exposure to sunlight, and is absorbed from foods as well. It is important for calcium absorption and bone growth. Vitamin D status is linked to the pathogenesis of skeletal and non-skeletal disorders. Vitamin D deficiency is relatively prevalent all over the world. In studies conducted in other countries, adolescents are thought to have increased risk of vitamin D deficiency. Still, data is lacking about the prevalence of vitamin D deficiency among healthy Afghan adolescents. Objective: The aim of this study was to determine the prevalence of and to identify factors associated with vitamin D deficiency and severe vitamin D deficiency among Afghan adolescents (10-18 years of age) diagnosed at French Medical Institute for Mothers and Children (FMIC), Kabul. Material and Methods: An analytical cross-sectional study design was conducted from Jun to Sep 2016. Blood samples were obtained, serum 25OHD levels were measured, and the patients were divided into five diagnostic categories according to their serum 25OHD concentrations. 1) Sufficiency ≥30-100 ng/ml; 2) Insufficiency ≥20-30 ng/ml; 3) Deficiency <20 ng>/ml; 4) Severe deficiency <10 ng>/ml; 5) Intoxication >150 ng/ml. Collection of samples were made at Clinical Laboratory of FMIC and serum 25OHD analyses were carried out in the Biochemistry section. Results: A total of 308 adolescents were part of the sample for the final analysis. Of all, 202 (65.6%) were females and 106 (34.5%) were males. Out of total, 238 (77.3%) had either insufficiency, deficiency or severe deficiency of vitamin D. Among those, a large number of the participantss i.e., 107 (34.7%) had severe vitamin D deficiency, 81 (26.3%) had vitamin D deficiency, 50 (16.2%) had vitamin D insufficiency, and only 70 (22.7%) had vitamin D sufficiency. There were two cases of vitamin D intoxication, who were excluded from the study. Gender, sun-exposure, usage of sun protector, calcium+vitamin D supplement intake, Vitamin D rich foods intake, regular milk intake, the type of living in yards or apartments, skin colour of participants, and BMI were found as significant factors associated with vitamin D level Conclusion: There was a high prevalence of vitamin D deficiency among adolescents who visited a tertiary healthcare facility in Kabul. Low serum vitamin D concentration is prevalent among general Afghan population. Screening and ongoing investigation for vitamin D deficiency should be considered for all adolescents in the country. Based on our results, the
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اختری بیگم [اہلیہ مولانا سعید احمد اکبر آبادی]

[اہلیہ،مولانا سعیداحمد اکبرآبادی]
میری اہلیہ!اختری بیگم کے انتقال پرملال پرجو دو ماہ کی شدید علالت کے بعد ۳۰ / شعبان المعظم مطابق ۱۴/جولائی کوعصر اورمغرب کے درمیان ہوا۔جن دوستوں، عزیزوں نے برصغیر ہندوپاک اوربیرونی ممالک سے تعزیت کے خطوط و ٹیلگرام بھیجے ہیں اورہندوستان وپاکستان کے جن اخبارات نے تعزیتی نوٹ کے ساتھ اس خبر کوشائع کیاہے اورجن اداروں نے اپنے یہاں اجتماعی ایصال ثواب کااہتمام کیا ہے ان سب کی محبت وہمدردی کاتہہ دل سے نہایت شکرگذار ہوں اوردعاکرتا ہوں جزاھم اﷲ عنی جزاء خیرا۔
ساتھ ہی معذرت اس کی کرنی ہے کہ اس حادثہ نے ذہن وقلم کوجیسے مفلوج کردیاہے، چنانچہ برہان کے زیرنظر شمارہ کے لیے جب نظرات بھی نہیں جاسکے تواپنے ناتمام مضامین کے فائل سے ایک مضمون نکال کر بھرت پورا کر دیا ہے ، اس لیے قارئین کلکتہ کے سفرنامہ اورتبصروں کے لیے معذور تصور فرمائیں۔
[سعید اکبر آبادی، ۷/اگست۱۹۸۰ء]

 

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