اطہرؔ صدیقی(۱۹۳۵ء۔پ) کا اصل نام محمدیسیٰن صدیقی اور اطہرؔ تخلص کرتے تھے۔ آپ چوہان حال برہان پور تحصیل پسرور میں پیدا ہوئے۔ آپ معروف شاعر پروفیسر حفیظ صدیقی کے بھائی تھے۔ حفیظ صدیقی کی راہنمائی میں اطہر نے زمانہ طالب علمی میں شاعری کا آغاز کیا تو ان کا کلام ملک کے معروف ادبی رسائل و جرائد میں شائع ہونے لگا۔(۹۱۶)
اطہرؔ کا پہلا شعری مجموعہ’’ کاکل غم‘‘ غزلوں اور نظموں پر مشتمل ہے جو۱۹۸۷ء میں شائع ہوا۔دوسرامجموعہ کلام’’ذوق سفر‘‘ کے نام سے ۱۹۸۹ء میں صدیقی پبلی کیشنز لاہور سے طبع ہوا۔ یہ مجموعہ غزلیات پر مشتمل ہے۔ تیسرا شعری مجموعہ’’آبرؤے غم‘‘۱۹۹۰ء میں صدیقی پبلی کیشنز لاہور سے شائع ہوا۔ یہ مجموعہ بھی غزلیات پر مشتمل ہے۔ چوتھا شعری مجموعہ ’’گردِ مسافت‘‘غزلیات اور نظموں پر مشتمل ہے۔
اطہر ؔصدیقی کی شاعری کا بڑا موضوع عظمت انسان ہے ۔وہ اپنی شاعری میں حضور ؐ کی ذات اقدس کے شیدائی نظر آتے ہیں۔ ان کے نزدیک حضرت محمدؐ کی ہستی عظمت انسان کی علامت ہے۔ اور وہی مثالیِانسان کا نمونہ ہیں۔انھوں نے نعت میں ہی نہیں بلکہ اپنی نظم اور غزل میں بھی عظمتِ انسان کی حقیقت کا اظہار کیا ہے:
ذرے ذرے سے پوچھ دیکھا ہے
-دشت در دشت کون رہتا ہے
5کون رہتا ہے لا مکاں میں اب
3کس کی رعنائیوں کا چرچا ہے
(۹۱۷)
ƒاطہرؔ کی شاعری عزم و ہمت ،جوش ،جواں جذبوں ،جستجو اور بلند حوصلوں سے بھر پور شاعری ہے ۔وہ اپنی شاعری میں کہیں بھی پست ہمت نظر نہیں آتے۔ان کے ہاں جوش اور جذبات کی شدت قاری کے حوصلے کو بلند...
ABSTRACT: Qazi Ayaz was one of the great scholars in the Knowledge of Hadith. He enjoys a unique status in his memory, narration and understanding of Hadith. He has vast knowledge of chains of Hadith, its transmitters, and their biographies. For acquiring this high position he always travelled to get the Hadith from its well-known experts, and used utmost care in getting the authentic chains of transmitters, so much so that he is considered an authority among the great scholars ofHadith. The methodology of Ayaz in the science of the transmission of Hadith is based upon research, accuracy and authentication ofthe text. He considers the science of transmission and narration. The origin and essence in authenticating the Hadith. He was strict in the criticism of the text of Hadith and emphasized on the narration of the Prophet’s words instead of allowing the narration of the meanings, unlike the other scholars of Hadith. Hence he held some special views, due to his long experience in Hadith. Some of his views are about: The comparison with the original hearing. The appropriate age while transmitting Hadith toothers. The omitting ofrepeated words in Hadith. The usage of the marks of dialect in the text ofHadith. The permission in narration ofthose Hadith about which he himselfdoes not have permission
Neuropeptide Y (NPY) acts at the hypothalamus to regulate the reproductive function by stimulating the release of GnRH from hypothalamus. In the present study a group of 5 female adult rhesus monkeys (Macaca mulatta), 5.5-9 years old, mean body weight of 10.31±0.90 kg and with menstrual cycle of 31 days was used. Changes in their body weight, behavior and sex skin color were observed throughout the cycle. Menstrual cycle of each monkey was monitored daily by recording the onset and duration of menstrual bleeding with vaginal swabs. Baseline profile of estradiol (E2), progesterone (P), prolactin (PRL) and growth hormone (GH) were measured by collecting blood sample (2 ml) on different days throughout the menstrual cycle of 31 days. Sequential blood samples (2 ml) were collected at an interval of 15 minutes for one hour before NPY administration for the hormonal baseline and for 2 hours and 15 minutes after NPY administration. In order to study the effect of NPY on plasma E2, P, PRL and GH levels on day 1 (menstrual phase), day 7 (follicular phase), day 15 (peri-ovulatory phase) and day 21 (luteal phase) of menstrual cycle, 200 μg of NPY in single bolus intravenous injection was given. Individual and mean body weight during the menstrual cycle was not significantly different. After NPY administration monkeys were relaxed and comfortable. Sex skin coloration changed progressively from whitish pink to deep red following menstrual to periovulatory phase and then decrease in colour intensity occurred during luteal phase. Baseline profile of estradiol showed that plasma E2 concentration was significantly high (P<0.001) in the periovulatory phase of menstrual cycle compared to menstrual, follicular and luteal phases. The luteal phase plasma E2 level was significantly low compared to follicular phase (P<0.003) but not significantly different from the menstrual phase. Plasma estradiol level 15 minutes after NPY administration increased non-significantly in all the four phases of menstrual cycle compared to baseline at 0 minute. Then, subsequent significant temporal increase till 45 minutes on day 1, 75 minutes on day 15, 60 minutes on day 7 and day 21 followed by subsequent significant temporal decrease. At the end of experiment plasma estradiol attained the basal level in all the four phases. Baseline profile of plasma progesterone showed significantly low levels during menstrual, follicular and periovulatory phases compared to the luteal phase. No significant difference was observed in the plasma P concentration between menstrual, follicular, and ovulatory phases. In all the four phases of menstrual cycle plasma progesterone level 15 minutes after NPY administration increased non-significantly followed by significant temporal increase till 60 minutes on day 1, 105 minutes on day 7, 135 minutes (i.e. till the end of experiment) on day 15 and 30 minutes on day 21. After then non-significant temporal decrease on day 7 and significant on day 1 (P<0.0002) and day 21 (P<0.0007) was observed. The baseline profile of plasma PRL showed that plasma PRL levels were significantly high during menstrual (P<0.013) and periovulatory phases (P<0.023) compared to luteal phase. Plasma prolactin level of follicular phase was non-significantly lower than menstrual and peri-ovulatory phases. The plasma prolactin levels of follicular and luteal phases were not different. In plasma prolactin concentration after 15 minutes of NPY bolus injection a non-significant rise was observed on day 1 followed by non-significant temporal increase till 30 minutes and then significant temporal decrease till the end of experiment. On day 7 non-significant and on day 15 significant increase in plasma prolactin level was observed 15 minutes after NPY administration followed by significant temporal decrease on day 7 (P<0.0005) and day 15 (P<0.009). On day 21 a non-significant decrease in plasma prolactin level after 15 minutes of NPY administration followed by significant temporal decreased till the end of experiment. Regression analysis of variance showed highly significant temporal decrease (P<0.0003). The base line plasma in all the four phases of menstrual cycle GH levels in all the four phases of menstrual cycle were non-significantly different (P>0.05). NPY administration inhibited the plasma GH level in all the four phases of menstrual cycle. On day 1 (menstrual phase) of menstrual cycle plasma growth hormone level 15 minutes after NPY administration decreased non-significantly with subsequent non-significant temporal decrease till 45 minutes followed by significant temporal increase till the end of experiment. A highly significant decrease in plasma GH level was observed on day 7 (follicular phase) and non-significantly on day 15 (periovulatory phase) and day 21 (luteal phase) of menstrual cycle 15 minutes after NPY administration followed by non- significant temporal decrease on day 7 and day 15, but significant temporal decrease on day 21 (P<0.004) till the end of experiment. These results show that NPY has stimulatory and inhibitory effects on the ovarian and pituitary hormones by acting as a modulator, neurotransmitter and neurohormone. NPY has applications in pharmacological fields and can be used for further research.