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Home > A Randomized Controlled Trial of the Effect of Additional Ultrasound Therapy to Analgesia Treatment Protocol for Acute Low Back Pain at Akuh N

A Randomized Controlled Trial of the Effect of Additional Ultrasound Therapy to Analgesia Treatment Protocol for Acute Low Back Pain at Akuh N

Thesis Info

Author

Mohammedali, Shamshudin

Department

General Surgery (East Africa)

Program

MMed

Institute

Aga Khan University

Institute Type

Private

City

Karachi

Province

Sindh

Country

Pakistan

Thesis Completing Year

2010

Thesis Completion Status

Completed

Subject

Medicine

Language

English

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676728034631

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Background: Acute low back pain is a common condition that is encountered by many physicians. Varied treatments are instituted in its management with no defined standard protocol in our institution. Additional physiotherapy has had minimal impact in terms of pain control and the time to return to work in the available literature. Controversy remains regarding effectiveness of ultrasound physiotherapy and its role in management of acute low back pain. Objective: To investigate the effectiveness of the addition of ultrasound physiotherapy to analgesia in patients with acute low back pain at the Aga Khan University Hospital, Nairobi. Methods: A randomized controlled trial was conducted to compare the effect of addition of ultrasound therapy to a defined analgesia protocol in patients presenting with acute low back pain at our institution. The primary outcome was reduction in pain and a secondary outcome of disability was analyzed. Seventy four (74) cases (37 in each arm) were needed to detect a 5 point difference in the Oswestry Disability Index score with a power of 80%. The effect of additional ultrasound on disability and symptom relief was evaluated using the mean change in Oswestry disability index (ODI) and visual analogue scale score for pain (VAS), respectively. Patients were followed up for a minimum of 4 weeks with assessment using the ODI and VAS at weekly clinic visits. Analysis: Data analysis was performed using SPSS version 17.0 and STATA-10 software. Difference in the means was compared using the student t-test and the Mann-Whitney U test to compare non parametric data such as the individual ODI scores. A p-value of <0.05, by convention, was considered to be a statistically significant result. Results: A total of one hundred and eight (108) patients were screened of whom 34 were excluded and 74 were eligible. Thirty six (36) patients were allocated to the analgesia with additional ultrasound group and 38 to the analgesia alone group. There was no difference in the mean change in the ODI score between the two groups at any of the four follow up visits after initiation of treatment. Mean difference in change of ODI (95% confidence interval) was -3.2(-7.0 to 0.6) after the first week, 2.96(-1.3 to 7.2) after the second and 1.90(-2.3 to 6.1) after the third week, p=0.36, 0.17 and 0.096 respectively. There was also no difference detected in the mean change of VAS score in between the two groups at the first and
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انجمن پنجاب

تعارف:
اس انجمن کا پورا نام "انجمن اشاعت مطالب مفیدہ پنجاب" ہے یہ انجمن لاہور میں جنوری 1865 میں قائم ہوئی۔ محمدحسین آزاد اور ڈاکٹر لائٹنر نے کوششیں کی۔محمد حسین آزاد نے اپنے کچھ جدید اور اہم نظریات کو عملی صورت دینے کے لئے اس انجمن کو استعمال کیا اور اس سے لوگوں میں ایک فعال ادبی تحریک پیدا کی۔
انجمن پنجاب کے مقاصد:
انجمن پنجاب کے درجہ ذیل مقاصد تھے:
1 :قدیم مشرقی علوم کا احیائ۔
2 : صعنت و تجارت کا فروغ ۔
3: کے لوگوں میں دیسی زبان کے ذریعے علوم مفیدہ کی اشاعت کرنا ۔
4: علمی و ادبی ،معاشرتی اور سیاسی مسائل پر بحث کرنا۔
5:صوبے کے بارسوخ اہل علم طبقات اور افسران حکومت میں رابطہ قائم کرنا۔
6: پنجاب اور ہندوستان کے دوسرے فرقوں کے ساتھ روابط اور تعلقات کی مضبوطی۔
ادبی خدمات
محمد حسین آزاد اس انجمن کے روح رواں تھے اس انجمن سے پہلے مشاعرے کی روایت موجود تھی لیکن وہ روایت طرحی غزلوں کی تھی اس انجمن نے نئی طرح کے مشاعرے شروع کئے یعنی مختلف موضوعات پر نظمیں کہی جاتی تھیں ہر مشاعرے میں ایک موضوع دے دیا جاتا تھا جس پر مختلف شعراء لکھ کر لے آتے تھے اس لحاظ سے اس انجمن نے مشاعروں کی طرز میں ایک نیا رجحان پیدا کیا ان مشاعروں میں نظمیں پڑھی جاتی تھیں اس لیے ان کو مناظموں کا نام دیا گیا۔
موضوعی نظم لکھنے کا رجحان:
موضوعی نظم لکھنے کا اولین تجربہ آزاد نے نہیں کیا بلکہ اس سے پہلے زمانہ قدیم میں اس کی روایت موجود تھی مثلا سلطان محمد قلی قطب شاہ کی کلیات میں نظمیں ہیں اس کے علاوہ دکنی دور میں مثنویاں بھی لکھی گئیں۔جو نظم ہی کا ایک حصہ ہیں اس کے علاوہ نظیر اکبر آبادی نظم روایت میں بہت بڑے شاعر ہیں۔ان...

Use of Intra Uterine Devices in Family Planning

Contraception is generally divided into two types, namely the Long Term Contraception Method (MKJP) and the Non Long Term Contraception Method (Non MKJP). Side effects of using injection contraceptives; There is a change in menstrual pattern, such as irregularity, bleeding, spotting, or bleeding for up to 10 days. Intra Uterine Devices (IUD) are long-term contraceptives that are inserted into the uterus. The advantages of this contraception include high effectiveness of about 0.6 to 0.8 pregnancies per 100 women, failure in 125 to 170 pregnancies. There are several disadvantages to its use, such as bleeding (spotting) between menstruation, excessive menstrual pain, longer menstrual periods, and heavy bleeding at the time of menstruation.

Computational Analysis of the Abiotic Stress Related Wrky Transcription Factor Family in Cereal Group for the Identification of Snps

Plants are unable to remove and predict different environmental stresses so they acquire number of mechanism to adjust these changes. Plants receive stimulations from external environment and pass these to the defense response genes, which show their responses, there are number of environmental stresses, which categorized into biotic and abiotic stresses. There are number of transcriptional factors, which control these stresses. Draught, salinity, water and UV radiations are some major stresses, which are reducing the productivity of plants in the world. The most important transcriptional factors are WRKY transcription factor in plants. These factors control number of development events and stresses responses in plants. These WRKY proteins consist of highly specific domain and they interact with other proteins due to these domains. WRKY domain act very important role against the environmental stresses and in the development of plants. WRKY protein has quick, short-lived and related to particular tissue expression under different environmental stresses. WRKY transcriptional factors carry out different function in plants like growth, development metabolism and transduction. WRKY are largest transcription factors which are highly plant-specific transcription factor and they are named due to highly preserved amino acid WRKYGQK in the N-terminus. The number of sequenced genome has been increased at very large amount which assist the evolution of WRKY protein family. Many species of plants have different numbers of WRKY genes which baised on their zinc finger motif. There are 97 WRKYs in Oryza nivara, 102 WRKYs in Oryza sativa, 171 WRKYs in Triticum aestivum, 116 WRKYs inZea mays species etc. Mosses contains 30-40 WRKY genes which were previously consisder as not plants species. Comparative genomic studies with bio-computational techniques show that these genes are present mostly in plant species. The evaluation and due to verities of plants species show that these transcription factors related to specific regulator families. Due to presence of SNPs in DNA sequence of different plants they show different mechanism for different transcriptional factors. In our present study we particularly focused on abiotic stresses and identified the SNPs which are present in plants due to which their stress mechanism changes. Our study reveals that SNPs are very important tools to show genetic relationship between different plants species.