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Home > Acceptability and Adequacy of Vaginal Self Sampling for Hpv Dna Testing in Cervical Cancer Screening Among Women Attending a Tertiary Hospital Clinics in Nairobi Kenya

Acceptability and Adequacy of Vaginal Self Sampling for Hpv Dna Testing in Cervical Cancer Screening Among Women Attending a Tertiary Hospital Clinics in Nairobi Kenya

Thesis Info

Author

Salad, Sagal Omar

Department

Pathology (East Africa)

Program

MMed

Institute

Aga Khan University

Institute Type

Private

City

Karachi

Province

Sindh

Country

Pakistan

Thesis Completing Year

2019

Thesis Completion Status

Completed

Subject

Medicine

Language

English

Added

2021-02-17 19:49:13

Modified

2024-03-24 20:25:49

ARI ID

1676728035418

Similar


Background: Cervical cancer is a main concern of women’s health globally. In Kenya, Cervical cancer is the second most common cancer in women and the leading causes of cancer related deaths. Several screening methods exist including cytology, human papilloma virus DNA test and visual inspection with Acetic Acid or Lugol’s Iodine (VIA/VILI). The current screening rate uptake in Kenya is poor, HPV DNA self-sampling may have a role in increasing the screening uptake as many studies have shown that self-sampling for HPV DNA testing is acceptable, though some others favoured over self-sampling. This study aims to assess whether vaginal HPV self-sampling is acceptable to women, and if the results are adequate compared to cervical samples taken by health care provider (HCP). Study objective: Primary objective: to determine the acceptability of vaginal self-sampling for HPV DNA testing in cervical cancer screening among women attending tertiary hospital clinics in Kenya. Secondary objective: to determine the adequacy of self-sampling for HPV DNA compared to HCP sampling. Materials and Methods: A Cross sectional study was conducted at the gynaecology clinic from December 2018 to February 2019. One hundred twenty-four (124) women between 30 to 65 years of age were recruited. Women underwent self-sampling for HPV DNA, HCP sampling and Pap smear. Afterwards, the participants filled a post self-sampling acceptability questionnaire. A Likert scale was used to assess patient’s acceptance to self-collected sampling. Results: The mean age of the participants was 40.3years. The overall acceptability score for self-sampling was 23.2 out of 25 indicating a high acceptability rate for HPV DNA self-sampling. For the adequacy, a Cohen kappa of 0.935 was found which indicates a high level of agreement among the self –sampling and HCP collected samples. The HPV DNA prevalence was 15.3% in HCP samples and 13.7 in self-samples. Conclusion: The study demonstrated that HPV DNA self – sampling was highly acceptable and concordance rate was high between the self –sampling and the HCP sample results. Therefore, it is hoped that self- collection may have potential for increasing cervical cancer screening in Kenya.
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مرزا سلطان احمد

مرزا سلطان احمد
افسوس ہے کہ اعظم گڑھ کی ممتاز مقبول شخصیت مرزا سلطان احمد صاحب رٹائر ممبر بورڈ آف ریونیو نے طویل علالت کے بعد گزشتہ ۱۷؍ فروری کو انتقال کیا وہ پرانے علیگ اور اپنے زمانہ کے لائق ترین عہدہ داروں میں تھے، اپنی قابلیت سے ڈپٹی کلکٹری سے کلکٹری اور بورڈ کی ممبری تک ترقی کی اور جہاں رہے اپنی دیانتداری اور شرافت سے مقبول و نیک نام رہے، بڑے عہدہ داروں میں ایسے شریف اور خلیق انسان کم دیکھنے میں آئے ہیں، ان کا خمیر ہی اخلاق و شرافت سے گوندھا گیا تھا، ادنی و اعلیٰ ہر شخص کے ساتھ ان کا اخلاق یکساں تھا، ہر ملنے والے کے ساتھ کوئی نہ کوئی ایسی خصوصیت ضرور برتتے تھے جس سے اس کو یہ محسوس ہوتا کہ وہ اس کے ساتھ خاص تعلق رکھتے ہیں۔
بڑے وضعدار، فیاض اور مہمان نواز تھے جس سے جس قسم کے تعلقات تھے، اس کو عمر بھر نباہا، ملازمت کے زمانہ میں ان کا دستر خوان بڑا وسیع اور گھر مستقل مہمان خانہ تھا، ان کے اعزہ و احباب میں سے کوئی نہ کوئی ان کے یہاں مستقل مقیم رہتا تھا اور جس کو ضرورت ہوتی اس کی نقدی سے بھی مدد کرتے تھے، ہر حاجت مند کی مدد کے لیے ہر وقت تیار رہتے تھے اور اس کے لیے ایسے کام کر گزرتے تھے جس کی ہمت ہر شخص نہیں کرسکتا، وہ بڑے تنخواہ دار تھے لیکن جو کچھ کمایا سب صرف کردیا، اعظم گڑھ میں دو ہی ایسے شخص تھے جنھوں نے بہت پیدا کیا، مگر اپنے بعد کچھ نہیں چھوڑا، ایک مرزا صاحب، دوسرے اقبال سہیل مرحوم ملازمت سے ریٹائر ہونے کے بعد حکومت نے ان کے سامنے پبلک سروس کمیشن کی ممبری پیش کی، مگر انھوں نے وطن چھوڑنا پسند نہ کیا اور اعظم...

فقہ اسلامی میں قسامت کا تصور

Islam lays great emphasis on security and the sanctity of human life. The holy Quran terms killing of an innocent person as killing of the whole humanity. It prohibits unjust killing of human being in unequivocal terms. The holy Qur’an and Sunnah terms killing of an innocent person as one of the greatest sins. An eternal torment is the destiny of a killer who takes life of a person unjustly. However, it is also a bitter fact that hardly   a crime free society could be found   anywhere in the world. Peace prevails only in those societies where culprits are brought to justice. This is why Islamic penal code has prescribed punishments for all kinds of crimes. It has prescribed punishment of Qisâs in case of intentional murder and Diyat (blood money in case of killing of a person by mistake, it is also due in case if remission is made by the heirs in intentional murder case). To prove the crime of murder, testimony of two reliable witnesses or confession of the killer is required before the court. However, if a corpse is found in a place where killer is unknown and witnesses are unavailable,    then Islam enjoins the process of Qasâmah to safeguard rights of the heirs of the deceased. Qasâmah is a process of taking oath by fifty persons selected by the heirs of the slain. In this article the concept of Qasâmah has been elaborated. It  has three parts , in the  first part conditions for the validity of  Qasâmah has been elaborated, while in the second part its process has been discussed with elaborate opinions  of jurists  regarding taking of  oath, as some of them opine that  the  heirs of the slain  have to take oath, mentioning name of the killer,   while others say  oath will be taken by the defendants that they  didn’t kill him, Both these opinions  have been discussed by producing arguments of  the both sides. While in the third part the issue of Qisâs and Diyat has been discussed as according to some jurists the Qasâmah entails Qisâs while other say that it entails Diyat only; arguments of both sides have been discussed in detail.

Impact of Knowledge Management Practices on Organizational Performance in Telecom Sector of Balochistan

The core rationale behind the study is investigating the impact of knowledge management practices upon organizational performance of the companies associated with Telecom Sector in Balochistan. The four major objectives behind this research study are; first, determining whether there exist any knowledge management practices in the selected companies, secondly, to determine whether their performance is satisfactory, thirdly, to determine that there exists an empirical relationship linking knowledge management practices with organizational performance of those companies. At last, comes explaining the impact of knowledge management practices upon the organizational performance of those companies in terms of competitive advantage, better service delivery, creation of value, innovation, efficiency and productivity. An adopted questionnaire has been used for the collection of primary data in Quetta, Balochistan. The major companies related with the Telecom sector in Balochistan are PTCL, Ufone, and Mobilink. The study concentrates on the opinion of 301 employees of these companies operating in Quetta, Balochistan. Results have been compiled from 301 filled in questionnaires with tables. It is revealed by the results that knowledge management practices such as orientation towards knowledge, organizational learning, development of innovative culture, individual-based approach, and competence development have significant impact on organizational performance of the three selected companies of Balochistan. The results have also demonstrated that knowledge management practices are having positive association with the organizational performance of these companies. This research proves that organizational performance gets better with the introduction and implementation of these knowledge management practices.